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AAT Bioquest

Anti-Follicle-stimulating hormone antibody *Mouse anti-human, monoclonal IgG1*

Follicle-stimulating hormone (FSH) is a 35.5 kDa glycoprotein polypeptide hormone synthesized and secreted by the gonadotropic cells of the anterior pituitary gland. It is essential for regulating the development, growth, pubertal maturation and reproductive processes of the body. In clinical biology, FSH levels can be used to evaluate physiological disorders. For instance, FSH and luteinizing hormone levels are elevated in primary gonadal failure, primary hypogonadism, complete testicular feminization syndromes and menopause. In pituitary or hypothalamus FSH and LH levels are both decreased. Anti-FSH monoclonal antibodies are highly sensitive for the detection of human follicle-stimulating hormones. They can be used for a broad range of immunoassays such as lateral-flow immunoassays (LFIA), chemiluminescence immunoassays (CLIA) and rapid sandwich immunoassays.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of Anti-Follicle-stimulating hormone antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024

Ordering information

Price
Unit size
50 ug
1 mg
Catalog Number
Quantity
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Additional ordering information

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Antibody properties

Other names
Hostmouse
Reactivityhuman
ApplicationELISA; CLIA; LFIA

Storage, safety and handling

Intended useResearch Use Only (RUO)
Clinical comparison of FSH assay and commercial diagnostic assay: 72 clinical blood samples were separately tested using AAT Bioquest’s anti-FSH monoclonal antibodies on CLIA platform and a commercial diagnostic kit from Siemens. Data from this study were analyzed using the Passing-Bablok regression method.
Clinical comparison of FSH assay and commercial diagnostic assay: 72 clinical blood samples were separately tested using AAT Bioquest’s anti-FSH monoclonal antibodies on CLIA platform and a commercial diagnostic kit from Siemens. Data from this study were analyzed using the Passing-Bablok regression method.
Clinical comparison of FSH assay and commercial diagnostic assay: 72 clinical blood samples were separately tested using AAT Bioquest’s anti-FSH monoclonal antibodies on CLIA platform and a commercial diagnostic kit from Siemens. Data from this study were analyzed using the Passing-Bablok regression method.
Calibration curve for FSH sandwich chemiluminescence immunoassay (CLIA): all MAbs were tested in pairs as capture and detection antibodies to select the best two-site MAb combinations for the development of a quantitative sandwich immunoassay. Detection antibodies were labeled with horse reddish peroxidase (HRP) and capture antibodies were coated onto 96-microwell plate. The best selected MAb pair for human FSH immunoassays is (capture-detection respectively): Cat # V100175 Clone 1 – Cat#V100175 Clone 2