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Anti-Epididymal secretory protein 4 antibody *Mouse anti-human, monoclonal IgG1*

Human epididymis secretory protein E4 (HE4) is a protein encoded by the WFDC2 gene in humans. This gene is expressed primarily in pulmonary epithelial cells, but has found to be expressed in some ovarian cancers. As such, HE4 serves as a serum biomarker in women with a pelvic mass to distinguish benign from malignant disease and as a tumor marker for ovarian cancer. Anti-HE4 monoclonal antibodies are highly sensitive for the detection of human HE4. They can be used for a broad range of immunoassays such as chemiluminescence immunoassay (CLIA) and rapid sandwich immunoassays.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of Anti-Epididymal secretory protein 4 antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024

Ordering information

Price
Unit size
50 ug
1 mg
Catalog Number
Quantity
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Additional ordering information

Telephone1-800-990-8053
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Antibody properties

Other names
Hostmouse
Reactivityhuman
ApplicationELISA; CLIA

Storage, safety and handling

Intended useResearch Use Only (RUO)
Determination of clinical samples using two MAb combinations on CLIA platform: 40 specimens were tested using two antibody combinations on a CLIA platform and a commercial comparison assay. The antibody combinations used were (capture-detection respectively): Mab combination A:  Cat# V100060 Clone 2- Cat# V100060 Clone 3;Mab combination B:  Cat# V100060 Clone 3- Cat# V100060 Clone 1.
Determination of clinical samples using two MAb combinations on CLIA platform: 40 specimens were tested using two antibody combinations on a CLIA platform and a commercial comparison assay. The antibody combinations used were (capture-detection respectively): Mab combination A:  Cat# V100060 Clone 2- Cat# V100060 Clone 3;Mab combination B:  Cat# V100060 Clone 3- Cat# V100060 Clone 1.
Determination of clinical samples using two MAb combinations on CLIA platform: 40 specimens were tested using two antibody combinations on a CLIA platform and a commercial comparison assay. The antibody combinations used were (capture-detection respectively): Mab combination A:  Cat# V100060 Clone 2- Cat# V100060 Clone 3;Mab combination B:  Cat# V100060 Clone 3- Cat# V100060 Clone 1.
Calibration curves for HE4 in sandwich chemiluminescence immunoassay (CLIA): all monoclonal antibodies were tested in pairs as capture and detection antibodies to select the best two-site MAb combinations for the development of a quantitative sandwich immunoassay. The best selected MAb combinations for quantification of human HE4 are (capture-detection respectively): Mab combination A:  Cat# V100060 Clone 2- Cat# V100060 Clone 3; Mab combination B:  Cat# V100060 Clone 3- Cat# V100060 Clone 1.