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Zinc finger protein GLI1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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Ethyl (4R,4aR,5R,11bS)-5-hydroxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxylateIC50740.0 [1], 860.0 [2]
Methyl (4R,4aR,5R,11bS)-5-hydroxy-4,9,11b-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1,3]benzoxazole-4-carboxylateIC50640.0 [1], 1090.0 [2]
Betulinic acidIC5032000.0 [1]
CyclopamineIC505000.0 [1]
6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-oneIC501800.0 [1]
ZerumboneIC507100.0 [1]
2-[[3-[[2-(Dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylanilineIC5040000.0 [1]
(1R,2S,5R,8S,9R,17R,18R,21S,24R,26S,27S)-5-Hydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetroneIC50620.0 [1]
5,6-Epxoyphysalin BIC50660.0 [1]
Alphitolic acidIC5042000.0 [1]
Ceanothic acidIC50200000.0 [1]
Arcyriaflavin CIC501800.0 [1]
6-HydroxystaurosporinoneIC501800.0 [1]
6,7-Dihydroxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaene-12,14-dioneIC501800.0 [1]
Colubrinic acidIC5038000.0 [1]
CID 46898044IC501600.0 [1]
(S)-2-(3-Benzoylphenyl)-N,N-bis(4-hydroxyphenethyl)propanamideIC509400.0 [1]
(S)-2-(3-Benzoylphenyl)-N-(4-hydroxyphenethyl)propanamideIC5011400.0 [1]
(S)-2-(3-Benzoylphenyl)-N-(4-hydroxyphenethyl)-N-propylpropanamideIC506900.0 [1]
Ceanothanolic acidIC50133000.0 [1]
(S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)propanamideIC5011400.0 [1]
CID 46898040IC502600.0 [1]
Methyl (4R,4aR,5R,11bS)-5-hydroxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxylateIC5015850.0 [1]
Methyl (4R,4aR,5R,11bS)-5-acetyloxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxylateIC5012530.0 [1]
[(4R,4Ar,5R,11bS)-4,11b-dimethyl-4-(methylcarbamoyl)-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-5-yl] acetateIC5025000.0 [1]
(4R,4Ar,5R,11bS)-5-hydroxy-N,4,11b-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxamideIC5025000.0 [1]
Methyl (4R,4aR,5R,11bS)-5-acetyloxy-4,9,11b-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1,3]benzoxazole-4-carboxylateIC5025000.0 [1]
(4R,4Ar,5R,11bS)-4-(hydroxymethyl)-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-5-olIC5025000.0 [1]
[(4R,4Ar,5R,11bS)-4-(benzylcarbamoyl)-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-5-yl] acetateIC508980.0 [1]
Tert-butyl N-[3-[[(4R,4aR,5R,11bS)-5-hydroxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carbonyl]amino]propyl]carbamateIC5025000.0 [1]
Methyl (4R,4aR,5R,11bS)-5-benzoyloxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxylateIC5025000.0 [1]
[(4R,4Ar,5R,11bS)-5-acetyloxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-yl]methyl acetateIC5025000.0 [1]
Methyl (4R,4aR,5R,11bS)-5-hydroxy-4,8,11b-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1,2]benzoxazole-4-carboxylateIC5025000.0 [1]
4-O-[(4R,4Ar,5R,11bS)-4-methoxycarbonyl-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-5-yl] 1-O-methyl butanedioateIC5012340.0 [1]
[(4R,4Ar,5R,11bS)-4,11b-dimethyl-4-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propylcarbamoyl]-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-5-yl] acetateIC5025000.0 [1]
Methyl (4R,4aR,5R,11bS)-5-acetyloxy-4,8,11b-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1,2]benzoxazole-4-carboxylateIC5025000.0 [1]
(4R,4Ar,5R,11bS)-N-benzyl-5-hydroxy-4,11b-dimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-f][1]benzofuran-4-carboxamideIC505380.0 [1]
Items per page: 1 - 10 of 37
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References

This online tool may be cited as follows

MLA

"Quest Database™ Zinc finger protein GLI1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/zinc-finger-protein-gli1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Zinc finger protein GLI1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/zinc-finger-protein-gli1-inhibitors-ic50-ki.
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