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Xaa-Pro aminopeptidase 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
ApstatinIC502900.0 [1], 6100.0 [2]
CID 10336627IC50230.0 [1], 430.0 [2]
(2S)-1-[(3R,4S)-4-Amino-3-hydroxy-6-methylheptanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC501000000.0 [1], 2000000.0 [2]
(2S)-1-[(2S,3S)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC5058000.0 [1], 88000.0 [2]
(2S)-1-[(2S,4R)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-4-hydroxypyrrolidine-2-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50470000.0 [1], 600000.0 [2]
2-[(2S)-2-[[(2S)-1-Amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-phenylbutanoic acidIC502600.0 [1], 8400.0 [2]
(2S)-1-[(4R)-3-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-1,3-thiazolidine-4-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC5011000.0 [1], 18000.0 [2]
(2S)-1-[(2R,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC5030000.0 [1], 31000.0 [2]
(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50130.0 [1], 230.0 [2]
(2S)-1-[(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxamideIC5079000.0 [1], 89000.0 [2]
(2S)-N-[(2S)-1-Amino-1-oxopropan-2-yl]-1-[2-(hydroxycarbamoyl)cyclohexanecarbonyl]pyrrolidine-2-carboxamideIC501300000.0 [1], 9000000.0 [2]
(2S)-N-[(2S)-1-Amino-1-oxopropan-2-yl]-1-(2-sulfanylcyclopentanecarbonyl)pyrrolidine-2-carboxamideIC50300000.0 [1], 390000.0 [2]
(2S)-1-[(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]pyrrolidine-2-carbonyl]-N-[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC502800.0 [1], 3400.0 [2]
2-[[6-[(3R)-3-Amino-3-methylpiperidin-1-yl]-1,3-dimethyl-2,4-dioxopyrrolo[3,2-d]pyrimidin-5-yl]methyl]-4-fluorobenzonitrileIC5050000.0 [1]
(3R)-1-[(2S)-1-[(2S,4S)-4-Fluoro-1-[(2S)-4-methyl-2-sulfanylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-3-carboxylic acidIC503.7 [1]
(3S)-1-[(2S)-1-[(2S)-1-[(2S)-4-Methyl-2-sulfanylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-3-carboxylic acidIC5026.0 [1]
(2S)-2-[Methyl-[(2S)-1-[(2S)-1-[(2S)-4-methyl-2-sulfanylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoic acidIC503.9 [1]
(2R)-1-[(2S)-1-[(2S)-1-[(2S)-4-Methyl-2-sulfanylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acidIC509.7 [1]
Items per page: 1 - 10 of 18
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References

This online tool may be cited as follows

MLA

"Quest Database™ Xaa-Pro aminopeptidase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/xaa-pro-aminopeptidase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Xaa-Pro aminopeptidase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/xaa-pro-aminopeptidase-2-inhibitors-ic50-ki.
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