Voltage-gated calcium channel Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-Tert-butyl-8-[[[(1S,2S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropanecarbonyl]amino]methyl]-5-[3-(trifluoromethoxy)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide	IC50	800.0 [1]
	1-Benzyl-5-methyl-3-(piperidin-1-ylmethyl)indole	IC50	3400.0 [1]
	1-[(3-Chlorophenyl)methyl]-5-methyl-3-(piperidin-1-ylmethyl)indole	IC50	2200.0 [1]
	5-Methyl-1-[(3-nitrophenyl)methyl]-3-(piperidin-1-ylmethyl)indole	IC50	3000.0 [1]
	1-[(4-Fluorophenyl)methyl]-5-methyl-3-(piperidin-1-ylmethyl)indole	IC50	4800.0 [1]
	5-Methyl-1-[(4-methylphenyl)methyl]-3-(piperidin-1-ylmethyl)indole	IC50	3600.0 [1]
	1-[(4-Chlorophenyl)methyl]-5-methyl-3-(piperidin-1-ylmethyl)indole	IC50	3000.0 [1]
	5-Methyl-1-[(2-nitrophenyl)methyl]-3-(piperidin-1-ylmethyl)indole	IC50	1800.0 [1]
	1-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-3-(2,2,6,6-tetramethyloxan-4-yl)oxypyrazole	IC50	9.4 [1]
	1-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-3-(2,2,6,6-tetramethylthian-4-yl)oxypyrazole	IC50	6.0 [1]
	4-[1-(2-Methoxyphenyl)-5-(4-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylthiane 1,1-dioxide	IC50	3.0 [1]
	4-[1-(2-Methoxyphenyl)-5-(4-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylthiane 1-oxide	IC50	7.6 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethylthian-4-yl)oxypyrazole	IC50	5.9 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylthiane 1,1-dioxide	IC50	1.9 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-[(2,2,4,4-tetramethyloxetan-3-yl)methoxy]-1H-pyrazole	IC50	3.1 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylcyclohexan-1-one	IC50	9.7 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylcyclohexan-1-ol	IC50	39.0 [1]
	4-[2-(2-Methoxyphenyl)-5-(2,2,6,6-tetramethyloxan-4-yl)oxypyrazol-3-yl]benzonitrile	IC50	7.2 [1]
	4-[2-(2-Methoxyphenyl)-5-(2,2,6,6-tetramethylthian-4-yl)oxypyrazol-3-yl]benzonitrile	IC50	12.0 [1]
	4-[2-(2-Methoxyphenyl)-5-(2,2,6,6-tetramethyl-1,1-dioxothian-4-yl)oxypyrazol-3-yl]benzonitrile	IC50	2.4 [1]
	4-[2-(2-Methoxyphenyl)-5-(2,2,6,6-tetramethyl-1-oxothian-4-yl)oxypyrazol-3-yl]benzonitrile	IC50	14.0 [1]
	Tert-butyl 4-[5-(4-chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxypiperidine-1-carboxylate	IC50	30.0 [1]
	4-{[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3-yl]oxy}cyclohexanone	IC50	28.0 [1]
	1-Acetyl-4-{[5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3-yl]oxy}piperidine	IC50	26.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-N,N-dimethylpiperidine-1-carboxamide	IC50	14.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-1-methylsulfonylpiperidine	IC50	15.0 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(oxan-4-yloxy)pyrazole	IC50	15.0 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(thian-4-yloxy)pyrazole	IC50	28.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-1-(2,2,2-trifluoroethyl)piperidine	IC50	31.0 [1]
	1-[4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxypiperidin-1-yl]-2,2,2-trifluoroethanone	IC50	31.4 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxythiane 1,1-dioxide	IC50	30.0 [1]
	Tert-butyl N-[4-[5-(4-chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxycyclohexyl]carbamate	IC50	62.0 [1]
	N-[4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxycyclohexyl]-2,2,2-trifluoroacetamide	IC50	11.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-1-(trifluoromethylsulfonyl)piperidine	IC50	24.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-1-cyclopropylsulfonylpiperidine	IC50	9.0 [1]
	5-(4-Chlorophenyl)-3-(4,4-difluorocyclohexyl)oxy-1-(2-methoxyphenyl)pyrazole	IC50	41.0 [1]
	5-(4-Chlorophenyl)-3-(1,4-dioxaspiro[4.5]decan-8-yloxy)-1-(2-ethylphenyl)pyrazole	IC50	81.0 [1]
	Tert-Butyl 4-{[5-(4-chlorophenyl)-1-(2-ethylphenyl)-1H-pyrazol-3-yl]oxy}piperidine-1-carboxylate	IC50	50.0 [1]
	4-{[5-(4-Chlorophenyl)-1-(2-ethylphenyl)-1H-pyrazol-3-yl]oxy}-1-(methylsulfonyl)piperidine	IC50	98.5 [1]
	4-[5-(4-Chlorophenyl)-1-(2-propan-2-yloxyphenyl)pyrazol-3-yl]oxy-1-methylsulfonylpiperidine	IC50	21.5 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-1-propan-2-ylsulfonylpiperidine	IC50	36.0 [1]
	Tert-butyl-3-((5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3-yl)oxy)azetidine-1-carboxylate	IC50	67.0 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyloxan-4-yl)oxypyrazole	IC50	7.6 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(1-propan-2-ylsulfonylazetidin-3-yl)oxypyrazole	IC50	36.0 [1]
	5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(1-methylsulfonylazetidin-3-yl)oxypyrazole	IC50	31.0 [1]
	[3-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxyazetidin-1-yl]-phenylmethanone	IC50	85.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-propan-2-yloxyphenyl)pyrazol-3-yl]oxy-1-propan-2-ylsulfonylpiperidine	IC50	7.0 [1]
	3-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-N-methoxy-N-methylazetidine-1-carboxamide	IC50	14.0 [1]
	4-[3-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxyazetidin-1-yl]sulfonyl-3,5-dimethyl-1,2-oxazole	IC50	8.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxycyclohexan-1-amine	IC50	400.0 [1]
	4-[5-(4-Chlorophenyl)-1-(2-methoxyphenyl)pyrazol-3-yl]oxy-2,2,6,6-tetramethylthiane 1-oxide	IC50	1.5 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 51 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Voltage-gated calcium channel Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/voltage-gated-calcium-channel-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Voltage-gated calcium channel Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/voltage-gated-calcium-channel-inhibitors-ic50-ki.
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