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Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-nitrophenyl)sulfonylamino]pentanamideIC501300.0 [1], 2300.0 [2], 3800.0 [3]
CID 11570626IC5012800.0 [1]
CID 16137193IC5010.23 [1]
CID 44566163IC5022.91 [1]
CID 127034614IC5053.0 [1]
CID 127035881IC5036.0 [1]
CID 16214685IC5013.0 [1]
CID 44418758IC5027.0 [1]
3-[[4-[(1S)-1-[3-(2,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acidIC502600.0 [1]
3-[[4-[(1S)-1-[3-(3,4-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acidIC501700.0 [1]
3-[[4-[(1S)-1-[3-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acidIC502600.0 [1]
(2R,4S)-2-Benzyl-5-[(4-chlorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC50280.0 [1]
(2R,4S)-2-Benzyl-5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC50206.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propan-2-ylphenyl)sulfonylamino]pentanamideIC503440.0 [1]
(2R,4S)-2-Benzyl-5-[(4-ethylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC501130.0 [1]
(2R,4S)-2-Benzyl-5-[(4-cyanophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC501330.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]pentanamideIC502340.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methylphenyl)sulfonylamino]pentanamideIC501180.0 [1]
(2S,4S)-2-Benzyl-N-butyl-4-hydroxy-5-[(4-nitrophenyl)sulfonylamino]pentanamideIC501800000.0 [1]
(2R,4S)-2-Benzyl-5-[(4-fluorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC506030.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(1-hydroxyethyl)phenyl]sulfonylamino]pentanamideIC5040600.0 [1]
(2R,4S)-2-Benzyl-5-(2,3-dihydro-1H-inden-5-ylsulfonylamino)-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC5010000.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methylsulfonylphenyl)sulfonylamino]pentanamideIC5013300.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(trifluoromethoxy)phenyl]sulfonylamino]pentanamideIC50152000.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propylphenyl)sulfonylamino]pentanamideIC504200.0 [1]
(2R,4S)-2-Benzyl-5-[(4-butan-2-yloxyphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC5045800.0 [1]
(2R,4S)-2-Benzyl-5-[(3,4-dimethylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC5013300.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propoxyphenyl)sulfonylamino]pentanamideIC504200.0 [1]
(2R,4S)-2-Benzyl-5-[(4-butan-2-ylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC50152000.0 [1]
(2R,4S)-2-Benzyl-5-[(4-chlorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC504000.0 [1]
(2R,4S)-5-[(4-Acetylphenyl)sulfonylamino]-2-benzyl-4-hydroxy-N-[(1S,2R)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC505000.0 [1]
(2R,4S)-2-Benzyl-5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-4-hydroxy-N-[(1S,2S)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC506000.0 [1]
(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methoxyphenyl)sulfonylamino]pentanamideIC501020.0 [1]
(2R,4S)-5-[(4-Acetylphenyl)sulfonylamino]-2-benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC50426.0 [1]
(2R,4S)-5-(1,3-Benzodioxol-5-ylsulfonylamino)-2-benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamideIC503810.0 [1]
Items per page: 1 - 10 of 35
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References

This online tool may be cited as follows

MLA

"Quest Database™ Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/vasoactive-intestinal-polypeptide-receptor-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/vasoactive-intestinal-polypeptide-receptor-2-inhibitors-ic50-ki.
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