Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-nitrophenyl)sulfonylamino]pentanamide	IC50	1300.0 [1], 2300.0 [2], 3800.0 [3]
	CID 11570626	IC50	12800.0 [1]
	CID 16137193	IC50	10.23 [1]
	CID 44566163	IC50	22.91 [1]
	CID 127034614	IC50	53.0 [1]
	CID 127035881	IC50	36.0 [1]
	CID 16214685	IC50	13.0 [1]
	CID 44418758	IC50	27.0 [1]
	3-[[4-[(1S)-1-[3-(2,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid	IC50	2600.0 [1]
	3-[[4-[(1S)-1-[3-(3,4-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid	IC50	1700.0 [1]
	3-[[4-[(1S)-1-[3-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid	IC50	2600.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-chlorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	280.0 [1]
	(2R,4S)-2-Benzyl-5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	206.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propan-2-ylphenyl)sulfonylamino]pentanamide	IC50	3440.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-ethylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	1130.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-cyanophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	1330.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]pentanamide	IC50	2340.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methylphenyl)sulfonylamino]pentanamide	IC50	1180.0 [1]
	(2S,4S)-2-Benzyl-N-butyl-4-hydroxy-5-[(4-nitrophenyl)sulfonylamino]pentanamide	IC50	1800000.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-fluorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	6030.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(1-hydroxyethyl)phenyl]sulfonylamino]pentanamide	IC50	40600.0 [1]
	(2R,4S)-2-Benzyl-5-(2,3-dihydro-1H-inden-5-ylsulfonylamino)-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	10000.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methylsulfonylphenyl)sulfonylamino]pentanamide	IC50	13300.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[[4-(trifluoromethoxy)phenyl]sulfonylamino]pentanamide	IC50	152000.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propylphenyl)sulfonylamino]pentanamide	IC50	4200.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-butan-2-yloxyphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	45800.0 [1]
	(2R,4S)-2-Benzyl-5-[(3,4-dimethylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	13300.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-propoxyphenyl)sulfonylamino]pentanamide	IC50	4200.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-butan-2-ylphenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	152000.0 [1]
	(2R,4S)-2-Benzyl-5-[(4-chlorophenyl)sulfonylamino]-4-hydroxy-N-[(1S,2R)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	4000.0 [1]
	(2R,4S)-5-[(4-Acetylphenyl)sulfonylamino]-2-benzyl-4-hydroxy-N-[(1S,2R)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	5000.0 [1]
	(2R,4S)-2-Benzyl-5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-4-hydroxy-N-[(1S,2S)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	6000.0 [1]
	(2R,4S)-2-Benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-[(4-methoxyphenyl)sulfonylamino]pentanamide	IC50	1020.0 [1]
	(2R,4S)-5-[(4-Acetylphenyl)sulfonylamino]-2-benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	426.0 [1]
	(2R,4S)-5-(1,3-Benzodioxol-5-ylsulfonylamino)-2-benzyl-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide	IC50	3810.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 35 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/vasoactive-intestinal-polypeptide-receptor-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 22). Quest Database™ Vasoactive intestinal polypeptide receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/vasoactive-intestinal-polypeptide-receptor-2-inhibitors-ic50-ki.
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