Vascular endothelial growth factor A Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate	IC50	16600.0 [1]
	1-Benzyl-3-hydroxy-4-[[(4-methylcyclohexyl)amino]methyl]pyridin-2-one	IC50	27400.0 [1]
	3-[(1-Benzyl-3-hydroxy-2-oxopyridin-4-yl)methylamino]azepan-2-one	IC50	62900.0 [1]
	1-Benzyl-4-[[4-(6-chloropyridazin-3-yl)piperazin-1-yl]methyl]-3-hydroxypyridin-2-one	IC50	78000.0 [1]
	3-Hydroxy-1-(4-methylphenyl)sulfonyl-4-[(4-piperidin-1-ylpiperidin-1-yl)methyl]pyridin-2-one	IC50	27000.0 [1]
	1-Benzyl-4-[(4-benzylpiperazin-1-yl)methyl]-3-hydroxypyridin-2-one	IC50	12600.0 [1]
	1-Benzyl-3-hydroxy-4-[(3-imidazol-1-ylpropylamino)methyl]pyridin-2-one	IC50	42500.0 [1]
	4-[[4-(6-Chloropyridazin-3-yl)piperazin-1-yl]methyl]-3-hydroxy-1-(4-methylphenyl)sulfonylpyridin-2-one	IC50	19000.0 [1]
	1-Benzyl-3-hydroxy-4-[(2-methylsulfanylethylamino)methyl]pyridin-2-one	IC50	53000.0 [1]
	1-(4-Chlorobenzyl)-3-hydroxypyridin-2(1H)-one	IC50	7400.0 [1]
	1-[(3-Chlorophenyl)methyl]-3-hydroxypyridin-2-one	IC50	100000.0 [1]
	2-[[3-Hydroxy-1-(4-methylphenyl)sulfonyl-2-oxopyridin-4-yl]methyl-methylamino]acetic acid	IC50	2100.0 [1]
	4-(Azepan-1-ylmethyl)-3-hydroxy-1-[[2-(hydroxymethyl)phenyl]methyl]pyridin-2-one	IC50	29200.0 [1]
	4-[(Benzylamino)methyl]-1-[(4-chlorophenyl)methyl]-3-hydroxypyridin-2-one	IC50	42000.0 [1]
	1-Benzyl-3-hydroxy-4-[(1-phenylethylamino)methyl]pyridin-2-one	IC50	20600.0 [1]
	1-Benzyl-3-hydroxy-4-[[(2R)-2-(2-hydroxyethyl)pyrrolidin-1-yl]methyl]pyridin-2-one	IC50	53000.0 [1]
	3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide	IC50	5.27 [1]
	Apratoxin S4	IC50	0.32 [1]
	(3S,5S,7S,10S,16S,19S,22S,27S)-16-[(2S)-Butan-2-yl]-7-tert-butyl-3-hydroxy-22-[(4-methoxyphenyl)methyl]-5,17,19,20-tetramethyl-8-oxa-29-thia-14,17,20,23,30-pentazatricyclo[25.2.1.010,14]triacont-1(30)-ene-9,15,18,21,24-pentone	IC50	0.3 [1]
	(3S,5S,7S,10S,16S,19S,22S,27S)-16-[(2S)-Butan-2-yl]-7-tert-butyl-3-hydroxy-22-[(4-methoxyphenyl)methyl]-2,2,5,17,19,20-hexamethyl-8-oxa-29-thia-14,17,20,23,30-pentazatricyclo[25.2.1.010,14]triacont-1(30)-ene-9,15,18,21,24-pentone	IC50	0.47 [1]
	(2S,3S,5S,7S,10S,16S,19S,22S,27R)-16-[(2S)-Butan-2-yl]-7-tert-butyl-3-hydroxy-22-[(4-methoxyphenyl)methyl]-2,5,17,19,20-pentamethyl-8-oxa-29-thia-14,17,20,23,30-pentazatricyclo[25.2.1.010,14]triacont-1(30)-ene-9,15,18,21,24-pentone	IC50	0.12 [1]
	1-Benzyl-3-hydroxy-4-[[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]methyl]pyridin-2-one	IC50	53000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 22 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Vascular endothelial growth factor A Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/vascular-endothelial-growth-factor-a-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 20). Quest Database™ Vascular endothelial growth factor A Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/vascular-endothelial-growth-factor-a-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan