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Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-[5-(2,4-Difluoro-phenylsulfanyl)-4-nitro-thiophen-2-yl]-ethanoneIC508000.0 [1], 19330.0 [2]
1-(5-(2,3-Dichlorophenylthio)-4-nitrothiophen-2-yl)ethanoneIC504200.0 [1]
7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrileIC50420.0 [1]
CID 73349008IC5028000.0 [1], 28100.0 [2]
CID 122531786IC50750.0 [1], 980.0 [2]
4-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]phenolIC502500.0 [1], 4600.0 [2]
1-(5-Phenylsulfanyl-4-nitro-2-thienyl)ethanoneIC5031600.0 [1], 50000.0 [2]
4-[2-Amino-4-ethyl-5-(1-methylindazol-5-yl)pyridin-3-yl]phenolIC502000.0 [1], 63300.0 [2]
Ursolic acidIC507000.0 [1]
Bardoxolone methylIC5014080.0 [1]
XestoquinoneIC50130.0 [1]
Spongiacidin CIC503800.0 [1]
Methyl (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,11,12,14a,14b-dodecahydropicene-4a-carboxylateIC5025000.0 [1]
5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamideIC501340.0 [1]
USP7/USP47 inhibitorIC50420.0 [1]
Chembl4128416IC50490.0 [1]
3,5-Bis(4-hydroxyphenyl)pyridineIC5050000.0 [1]
Chembl4127578IC5022570.0 [1]
5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(4-methylphenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamideIC503650.0 [1]
5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(3-fluorophenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamideIC501350.0 [1]
1-[5-[(3,4-Dichlorophenyl)methylamino]-4-nitro-1,3-thiazol-2-yl]ethanoneIC5050000.0 [1]
1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl acetateIC5050000.0 [1]
1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl butanoateIC504490.0 [1]
5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(4-fluorophenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamideIC502650.0 [1]
1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanolIC506950.0 [1]
1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl benzoateIC5050000.0 [1]
N-Benzyl-1-[5-(3,5-dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanamineIC5026780.0 [1]
1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC50670.0 [1]
1-[5-(3,4-Dimethoxyphenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC5050000.0 [1]
1-[5-(2,3-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC509930.0 [1]
1-[5-(3,4-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC5018020.0 [1]
1-[5-(2,6-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC504490.0 [1]
1-[5-(2,4-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC5016750.0 [1]
1-[5-(3-Methoxyphenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC5050000.0 [1]
1-[5-(2,4-Difluorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanoneIC506120.0 [1]
N-Benzyl-5-(3,5-dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazole-2-carboxamideIC504210.0 [1]
5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-N-phenyl-1,3-thiazole-2-carboxamideIC5040490.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-oneIC50200.0 [1]
4-[6-Amino-5-(4-hydroxyphenyl)-4-methylpyridin-3-yl]phenolIC507600.0 [1]
3-[2-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]benzonitrileIC505200.0 [1]
4-[6-Amino-5-(4-hydroxyphenyl)-4-propylpyridin-3-yl]phenolIC5013600.0 [1]
3-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]benzonitrileIC502500.0 [1]
4-[6-Amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl]phenolIC50610.0 [1]
4-[2-Amino-4-ethyl-5-(1H-indazol-6-yl)pyridin-3-yl]phenolIC50480.0 [1]
4-[2-Amino-4-ethyl-5-(2-methylindazol-6-yl)pyridin-3-yl]phenolIC5063300.0 [1]
4-[6-Amino-5-(4-hydroxyphenyl)-4-propan-2-ylpyridin-3-yl]phenolIC5021400.0 [1]
CID 122531796IC509600.0 [1]
4-(6-Amino-4-ethyl-5-phenylpyridin-3-yl)phenolIC5022400.0 [1]
Chembl4125949IC50130.0 [1]
Chembl4127188IC5075.0 [1]
Chembl4129261IC50100.0 [1]
N-[3-[6-Amino-5-(4-hydroxyphenyl)pyridin-3-yl]phenyl]acetamideIC5015100.0 [1]
3-[4-(Aminomethyl)phenyl]-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC506.0 [1]
7-Bromo-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-oneIC50300.0 [1]
7-Bromo-3-[[4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-oneIC5046000.0 [1]
7-Bromo-3-[[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-oneIC5013000.0 [1]
3-Bromo-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC50300.0 [1]
Usp7-IN-3IC5022.0 [1]
Usp7-IN-4IC502400.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-pyrrolidin-1-ylethylamino)pyrimidin-4-oneIC5090.0 [1]
6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-propan-2-ylpyrazolo[4,3-d]pyrimidin-7-oneIC50560.0 [1]
3-(2-Fluorophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC5090.0 [1]
6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-phenylpyrazolo[4,3-d]pyrimidin-7-oneIC5030.0 [1]
3-(3-Hydroxyphenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC5039.0 [1]
3-[4-(Hydroxymethyl)phenyl]-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC5040.0 [1]
6-Anilino-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC501900.0 [1]
6-[2-(Dimethylamino)ethylamino]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC50120.0 [1]
3-Ethynyl-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC50240.0 [1]
6-[2-(Dimethylamino)ethoxy]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC507200.0 [1]
3-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzamideIC5030.0 [1]
3-(3-Hydroxy-3-methylbut-1-ynyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC50300.0 [1]
6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC5044000.0 [1]
6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-oneIC50130000.0 [1]
3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[3,2-d]pyrimidin-4-oneIC50115000.0 [1]
3-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzonitrileIC50150.0 [1]
3-(2-Aminophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC501400.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC5023000.0 [1]
6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-[3-(morpholin-4-ylmethyl)phenyl]pyrazolo[4,3-d]pyrimidin-7-oneIC50250.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-phenylethynyl)pyrimidin-4-oneIC502800.0 [1]
3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[2,3-d]pyrimidin-4-oneIC5087000.0 [1]
6-[2-(Dimethylamino)ethyl-methylamino]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC50390.0 [1]
6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-(1H-pyrazol-5-yl)pyrazolo[4,3-d]pyrimidin-7-oneIC5035.0 [1]
3-(3-Aminophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-oneIC5024.0 [1]
6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-prop-1-en-2-ylpyrazolo[4,3-d]pyrimidin-7-oneIC50330.0 [1]
6-Benzyl-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-oneIC5090000.0 [1]
CID 135567363IC5079200.0 [1]
4-(3-Pyrrolidin-3-yl-1,2,4-oxadiazol-5-yl)phenolIC50132000.0 [1]
4-(3-Piperidin-4-yl-1,2,4-oxadiazol-5-yl)phenolIC5097700.0 [1]
4-(4-Piperidin-4-yl-1,3-oxazol-2-yl)phenolIC5085200.0 [1]
4-[2,6-Diamino-5-(4-hydroxyphenyl)pyridin-3-yl]phenolIC508500.0 [1]
2-Amino-3,5-bis(4-hydroxyphenyl)pyridine-4-carbonitrileIC50200000.0 [1]
4-[3-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazol-5-yl]phenolIC50131000.0 [1]
3-Fluoro-4-(5-piperidin-4-yl-1,3-oxazol-2-yl)phenolIC5018400.0 [1]
4-[2-Amino-5-(2-chlorophenyl)pyridin-3-yl]phenolIC5033200.0 [1]
4-[6-Amino-5-(4-hydroxyphenyl)pyridin-3-yl]phenolIC5011100.0 [1]
4-(5-Piperidin-4-yl-1,3-oxazol-2-yl)phenolIC5032800.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(methylamino)pyrimidin-4-oneIC504200.0 [1]
3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-methoxyethylamino)pyrimidin-4-oneIC5012000.0 [1]
7-Cyclopropyl-3-[[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-oneIC5020000.0 [1]
4-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzamideIC5050.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/ubiquitin-carboxyl-terminal-hydrolase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/ubiquitin-carboxyl-terminal-hydrolase-7-inhibitors-ic50-ki.
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