Tyrosine- and threonine-specific cdc2-inhibitory kinase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	7.0 [1], 31.1 [2]
	6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one	Ki	0.8 [1]
	Dasatinib	IC50	202.0 [1]
	Dasatinib	Ki	0.5 [1]
	N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine	IC50	55000.0 [1]
	N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine	Ki	1870.0 [1]
	Bosutinib	IC50	704.0 [1]
	Bosutinib	Ki	12.7 [1]
	Saracatinib	IC50	10000.0 [1]
	Saracatinib	Ki	39.8 [1]
	Adavosertib	IC50	1340.0 [1]
	Adavosertib	Ki	470.0 [1]
	6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One	IC50	2700.0 [1]
	6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One	Ki	10.4 [1]
	6-(2,6-Dichlorophenyl)-8-methyl-2-(4-morpholin-4-ylanilino)pyrido[2,3-d]pyrimidin-7-one	IC50	55.0 [1]
	6-(2,6-Dichlorophenyl)-8-methyl-2-(4-morpholin-4-ylanilino)pyrido[2,3-d]pyrimidin-7-one	Ki	2.3 [1]
	2-Amino-3-phenyl-5-(pyridin-4-yl)benzamide	IC50	11430.0 [1], 57990.0 [2]
	4-Methyl-3-{[6-(Methylsulfonyl)quinolin-4-Yl]amino}phenol	IC50	177.0 [1], 775.0 [2]
	3-[[4-(1H-Indazol-4-ylamino)pyrimidin-2-yl]amino]benzamide	IC50	509.0 [1], 2440.0 [2]
	5-[(E)-2-(4-Hydroxy-2,6-dimethylphenyl)ethenyl]pyridine-3-carboxamide	IC50	876.0 [1], 14510.0 [2]
	2-[[5-Cyano-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzamide	IC50	340.0 [1], 787.0 [2]
	3-Methyl-5-[(7-pyridin-2-ylquinolin-4-yl)amino]phenol	IC50	543.0 [1], 9430.0 [2]
	N-Methyl-2-[[5-methyl-2-[3-(methylsulfonylmethyl)anilino]pyrimidin-4-yl]amino]benzamide	IC50	115.0 [1], 151.0 [2]
	2-[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide	IC50	270.0 [1], 352.0 [2]
	2,6-Difluoro-N-[3-[3-[2-(pyridin-3-ylamino)pyrimidin-4-yl]pyrazolo[1,5-b]pyridazin-2-yl]phenyl]benzamide	IC50	7560.0 [1], 18880.0 [2]
	3-[(7-Pyridin-4-ylquinolin-4-yl)amino]phenol	IC50	332.0 [1], 706.0 [2]
	6-Methyl-4-(2-thienyl)-2-thioxo-1,2,5,6,7,8-hexahydro[1,6]naphthyridine-3-carbonitrile	IC50	1200.0 [1]
	5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide	IC50	10000.0 [1]
	3-[5-Chloro-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-N-(2-hydroxyethyl)-4-methylbenzamide	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 29 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Tyrosine- and threonine-specific cdc2-inhibitory kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/tyrosine-and-threonine-specific-cdc2-inhibitory-kinase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Tyrosine- and threonine-specific cdc2-inhibitory kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/tyrosine-and-threonine-specific-cdc2-inhibitory-kinase-inhibitors-ic50-ki.
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