![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_92b8d37992246fbced555a93be51a36c.svg) | Chalcone | IC50 | 23000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_64135ce3574b760f99ba9edf3d828869.svg) | Megalip | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_3549a1e176d576b636d9dfdd15d1e470.svg) | 4'-Methoxychalcone | IC50 | 14000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_216ebc4899b28a2e0d7d959345435ccc.svg) | 3-Phenyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 6000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_be644f05d0a40c881e3b44b2d166a6dc.svg) | 6,7-Dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one | IC50 | 22000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_cfed7b3cd0b25f590a521ecbe29107bf.svg) | 3',4'-Dimethoxychalcone | IC50 | 8000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_0d4f56c275eb15c8383c3dd62f84921d.svg) | 2,4,4'-Trimethoxychalcone | IC50 | 29000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_ea54ad638e5d5ef07a11cf691af4d798.svg) | 3,4-Trimethoxychalcone | IC50 | 6000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_d0e46986775729631f264e4d354caa37.svg) | 1,3-Diethyl-5-(5-methyl-thiophen-2-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione | IC50 | 3400.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_c053991822885159a81cfce1fdc0823c.svg) | 4,4'-Difluorochalcone | IC50 | 25000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_ca2c8b320ed9a7b93b7321c3b78d807d.svg) | 3-(3,4-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one | IC50 | 15000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_30cc884c4bca0d347185efc4ff5431c5.svg) | (E)-1-[3,5-Dimethoxy-4-[(4-methoxyphenyl)methoxy]phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_928d60016a682707f7bdcfd04201f487.svg) | (1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[[2-[(2-propan-2-yloxypyridin-4-yl)amino]-5-quinolin-2-ylpyrimidin-4-yl]amino]cyclopentane-1,2-diol | IC50 | 31000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_2324e08550809a675d90f05b92453f3d.svg) | (1R,2S,3R,5R)-3-[[2-[(2-Cyclopropyloxypyridin-4-yl)amino]-5-quinolin-2-ylpyrimidin-4-yl]amino]-5-(hydroxymethyl)cyclopentane-1,2-diol | IC50 | 31000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_3463aabc566c6bf81b1b2c46ef924a79.svg) | (1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[[2-[(2-methoxypyridin-4-yl)amino]-5-quinolin-2-ylpyrimidin-4-yl]amino]cyclopentane-1,2-diol | IC50 | 31000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_2b277ea1fd955b220dfdb3cbc4abfc36.svg) | (1R,2S,3R,5R)-3-[[2-[(2,6-Dimethylpyridin-4-yl)amino]-5-quinolin-2-ylpyrimidin-4-yl]amino]-5-(hydroxymethyl)cyclopentane-1,2-diol | IC50 | 31000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_bff1060d3b28ee326f1d9497933ec8b8.svg) | (1R,2S,3R,5R)-3-[[2-[(2,6-Dimethylpyridin-4-yl)amino]-5-(4-phenyl-1,3-thiazol-2-yl)pyrimidin-4-yl]amino]-5-(hydroxymethyl)cyclopentane-1,2-diol | IC50 | 31000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_a7303fbfe414cdcdc0df192754cd4761.svg) | 6-Hydroxy-5-[(Z)-indol-3-ylidenemethyl]-1-(2-methylphenyl)-2-sulfanylidenepyrimidin-4-one | IC50 | 1800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_68a7cd1d0049fe3f32ac39ba4341a933.svg) | 5-(1H-Indol-3-ylmethylene)-2-thioxo-1,3-di-o-tolyl-dihydro-pyrimidine-4,6-dione | IC50 | 790.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_bd4de1d3e2383a1a91d3fa98f1ba20e8.svg) | 1,3-Diethyl-5-(1H-indol-3-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_1e825fd2c39c3c0d4f45d3e17ea718ea.svg) | 5-(1H-Indol-3-ylmethylene)-1,3-dimethyl-2-thioxo-dihydro-pyrimidine-4,6-dione | IC50 | 13000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_047d53be57fe92d6c9a62aaefa726f2d.svg) | 1,3-Diethyl-6-hydroxy-5-[(Z)-(5-phenylmethoxyindol-3-ylidene)methyl]-2-sulfanylidenepyrimidin-4-one | IC50 | 400.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_8ace1ed283b3f4d22216739b2e74d352.svg) | 1,3-Diethyl-6-hydroxy-5-[(Z)-(7-methylindol-3-ylidene)methyl]-2-sulfanylidenepyrimidin-4-one | IC50 | 600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_b06b41b929ab6bbd13e3c5f89ec5b6c8.svg) | 1,3-Diethyl-6-hydroxy-5-[(Z)-(5-nitroindol-3-ylidene)methyl]-2-sulfanylidenepyrimidin-4-one | IC50 | 5500.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_620399aa044910c28fae3a1aacadb067.svg) | 1,3-Diethyl-6-hydroxy-5-[(Z)-indol-2-ylidenemethyl]-2-sulfanylidenepyrimidin-4-one | IC50 | 10200.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_09307b3e2d2562017289d14d1e6df8a4.svg) | 2-(2,4-Dichlorophenyl)-N'-(pyridine-2-carbonyl)-1,3-thiazole-4-carbohydrazide | IC50 | 770.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4c9c11db2a4a6e3559fd8a47abaa7397.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one | IC50 | 8000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4c738405ec42e41cae96a9a8ce5729f3.svg) | (E)-1-[3-Methoxy-4-(pyridin-2-ylmethoxy)phenyl]-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_80ee73163282eb28b46f3553824cd1a3.svg) | (E)-1-[3-Methoxy-4-(pyridin-3-ylmethoxy)phenyl]-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_8ce58a6429c9ab16db724af572d36ed6.svg) | {4-[(E)-3-(5-Benzo[b]thiophen-2-yl-2,4-dimethoxy-phenyl)-acryloyl]-phenylsulfanyl}-acetic acid | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_44e5af886aaf2b5f3cb3ec012f8467fe.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-[4-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]phenyl]prop-2-en-1-one | IC50 | 17000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_af292d87ec1ca028256ae0893417578d.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-en-1-one | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_9b539761225e3c64013fbcbe99d5eb8f.svg) | 4-{2-Methoxy-4-[(E)-3-(2-methoxy-5-thiophen-2-yl-phenyl)-acryloyl]-phenoxymethyl}-benzoic acid | IC50 | 5000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_12847a1e8a80421310a825d124a949a5.svg) | (E)-1-(1,3-Benzodioxol-5-yl)-3-[2-methoxy-5-(5-methylthiophen-2-yl)phenyl]prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_9265771b0f6f24e1ffe3c9ba02bf93ce.svg) | (E)-3-(2-Methoxy-5-thiophen-2-ylphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_c08945b17ddd21bb3dbf091a58e53348.svg) | (E)-1-(4-Hydroxy-3-methoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_97722b1359734c94840bd99c1462e9f6.svg) | (E)-3-[3-(5-Acetylthiophen-2-yl)-4,5-dimethoxyphenyl]-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_5c8b004e872931cddb8acc3665aaa936.svg) | (E)-3-(2,4-Dimethoxy-5-thiophen-2-ylphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_156f193c117f759a6ca8381c05431ac5.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-(3,4-dimethoxyphenyl)prop-2-en-1-one | IC50 | 11000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_22b1c4edc1d9a769ad29259d03fd6d04.svg) | (E)-1-(3,4-Dimethoxyphenyl)-3-[2-methoxy-5-(4-methylthiophen-2-yl)phenyl]prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_fed3c104f013515ceac904be1f8d3b91.svg) | (E)-3-(4-Thiophen-2-ylphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 6000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_3a59a70abcbbb9e48262e157288aea0d.svg) | (E)-1-(2,5-Dimethoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4a4249a2a8d6f793e487adbee6ffd0ee.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2-methoxyphenyl]-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_fcc75bbd84806b2ab9e4e86054426ea0.svg) | (E)-1-(3,4-Dimethoxyphenyl)-3-(4-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 12000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_da0591896dff976d1e3e9352aa8198d7.svg) | (E)-3-(3,4-Difluorophenyl)-1-(2-methoxy-4-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_f4c5809b4c9750a33627b48c097daff6.svg) | (E)-1-(3,4-Dimethoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_721d98c4a4bb7f33d59dd9235c641db3.svg) | (E)-3-[2-Methoxy-5-(5-methylthiophen-2-yl)phenyl]-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_62a75c3954307801a7e42d0913e719a8.svg) | (E)-1-(3,4-Dimethoxyphenyl)-3-[2-methoxy-5-(5-methylthiophen-2-yl)phenyl]prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_8cfc020088646531537f5e42e43813b4.svg) | (E)-3-(4-Ethoxy-3-fluorophenyl)-1-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_9022fc3df23008bef87fed7bc344d4ac.svg) | (E)-1-(1,3-Benzodioxol-5-yl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_2420977c7d09fb6419399b6975d308bd.svg) | (E)-1-(2,6-Dimethoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_e996167762e8c791b91168d937546bde.svg) | (E)-1-[4-[(4-Aminophenyl)methoxy]-3-methoxyphenyl]-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_9baeb3494d43de80cc49fe6dce5e342e.svg) | (E)-1-(1,3-Benzodioxol-5-yl)-3-[2-methoxy-5-(4-methylthiophen-2-yl)phenyl]prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_436a58e4ca0928721bdfcefacd390405.svg) | (E)-1-(3,5-Dimethoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4c4f67e51fa4d42d3a7a7c6ac8a253bd.svg) | (E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_9fad3efd4e6a51cb973f69285aa33196.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2-methoxyphenyl]-1-(3,4-dimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_ee7f74a965c1c0843b878d7608ddf387.svg) | (E)-3-[2-Methoxy-5-(4-methylthiophen-2-yl)phenyl]-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_1b7baeadcbc144aac241ce9c995ba47a.svg) | (E)-1-[3-Methoxy-4-(pyridin-4-ylmethoxy)phenyl]-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_37b5e224d3f6828b11f858f83f114a2d.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2-methoxyphenyl]-1-(4-methoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_b2d56a12e822dcebf635eb4da58de9eb.svg) | (E)-1-(4-Methoxyphenyl)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_29b13a57efb9ac0458e19719d785423c.svg) | (E)-3-(2-Methoxy-5-thiophen-2-ylphenyl)-1-(2,4,6-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_6b910bfcbd7026f514429ca1ae5ad5cc.svg) | 1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione | IC50 | 130.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_aea99ef0d798a824851c07577d67cf09.svg) | 5-(5-Bromo-thiophen-2-ylmethylene)-1,3-diethyl-2-thioxo-dihydro-pyrimidine-4,6-dione | IC50 | 4500.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_bf035a8244af90a5772cd7d10d316a00.svg) | (E)-1-(4-Fluorophenyl)-3-(4-fluoro-3-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_64a55721d68ac3b748057010e0faa9c6.svg) | (E)-1-[3,5-Dimethoxy-4-(2-methoxyethoxy)phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 5000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_253f6fce3865c86ef65536fc4c30402e.svg) | (E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-[4-(cyclopropylmethoxy)-3,5-dimethoxyphenyl]prop-2-en-1-one | IC50 | 50000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_71e126187e94a74d8f696856d2e7a47b.svg) | (E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-(2,4,5-triethoxyphenyl)prop-2-en-1-one | IC50 | 15000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4d2f11e3060c7bb430ba101cb41796cc.svg) | (E)-1-[4-[(3,4-Dimethoxyphenyl)methoxy]-3,5-dimethoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_11192359ed714834f3d0bcfbb2850b26.svg) | (E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-(2,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_d0eb7ae6a6224c68e4f878f256e48272.svg) | (E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-(3,5-dimethoxy-4-phenylmethoxyphenyl)prop-2-en-1-one | IC50 | 50000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_eeeaad6fd1810e7070ea7612dc0ca1cc.svg) | (E)-1-(3,5-Ditert-butyl-4-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one | IC50 | 17000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_a1489c0ea102e3467729c2c6b105c4c2.svg) | (E)-1-(3,5-Ditert-butyl-4-methoxyphenyl)-3-phenylprop-2-en-1-one | IC50 | 9000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_ef190c150ba4e791f3a77960059c1bfc.svg) | (E)-1-[3-Methoxy-4-(3-methoxy-1,4-benzodioxin-2-yl)phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_bd44ae88cb16c6eaee93141e1f20d469.svg) | (E)-1-[3,5-Dimethoxy-4-[(3,4,5-trimethoxyphenyl)methoxy]phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_688b01dc5dfe32fe3e474b47a00dec68.svg) | (E)-3-(2-Methoxy-5-thiophen-2-ylphenyl)-1-phenylprop-2-en-1-one | IC50 | 5000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_be2c2e2acdf7b83a5abaff60b1d09bca.svg) | (E)-1-[4-(Furan-2-ylmethoxy)-3,5-dimethoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_f0892aaf220af5e271701c6363f2b3dc.svg) | (E)-1-[4-(3-Acetylphenyl)-2-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_468d059f74b1f2eb756a8c0ec18457ea.svg) | (E)-1-[3,5-Dimethoxy-4-(3-methoxy-1,4-benzodioxin-2-yl)phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_f91c615af356755cdf289bfcb38f1e81.svg) | (E)-1-[3,5-Dimethoxy-4-(thiophen-2-ylmethoxy)phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_3848cf29027965a0cd1f01428d41ec79.svg) | (E)-1-[5-(2,4-Dimethoxyphenyl)-2,4-dimethoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_390bf0d9f0ed08e76dfe3702afd3f740.svg) | (E)-1-[4-[(3,4-Dimethoxyphenyl)methoxy]-3-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_7bab1035240ed2236fd50e9e570f27cc.svg) | (E)-1-[4-(1,3-Benzodioxol-5-ylmethoxy)-3,5-dimethoxyphenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_165402adeb68a07aabd3a01d78ffc8b8.svg) | 3-(5-Bromo-2,4-dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)propan-1-one | IC50 | 50000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_fd76875ae5489e690e5c5803dd0b4a03.svg) | 3-(5-Bromo-2-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)propan-1-one | IC50 | 50000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_bbcfd7171fe6b9256fd5bb4578ea9ee3.svg) | (E)-3-(5-Bromo-2,4-dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_210beeccd9d04f47de989acf6ebf583e.svg) | 2-[5-Methoxy-2-[(E)-3-oxo-3-[4-(trifluoromethyl)phenyl]prop-1-enyl]-4-thiophen-2-ylphenoxy]-2-methylpropanoic acid | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_4499269ff1f2d5611b5742cd86af3bea.svg) | [4-Benzo[b]thiophen-2-yl-5-methoxy-2-((E)-3-oxo-3-phenyl-propenyl)-phenoxy]-acetic acid | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_c785a5621103e85fe491d988c75eefc5.svg) | Ethyl 4-[[2-methoxy-4-[(E)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-enoyl]phenoxy]methyl]benzoate | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_214b99b6192be8519a3245b4e31449b8.svg) | 2-[4-[(E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]prop-2-enoyl]phenoxy]-2-methylpropanoic acid | IC50 | 6000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_5acf7e9f906eaee6087abfdc22accb4b.svg) | Tert-butyl N-[4-[[2-methoxy-4-[(E)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-enoyl]phenoxy]methyl]phenyl]carbamate | IC50 | 50000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_917c0d0d56093f382ad2c63195c6e866.svg) | 2-[4-[(E)-3-(3,4-Dimethoxy-5-thiophen-2-ylphenyl)prop-2-enoyl]-2,6-dimethoxyphenoxy]acetic acid | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_7716e4350c3b752b4eae513f468431ae.svg) | 2-[2,6-Dimethoxy-4-[(E)-3-(2-methoxy-5-thiophen-2-ylphenyl)prop-2-enoyl]phenoxy]acetic acid | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_cedb357d21f9ba8cbe51ba0d8cac9cc6.svg) | (E)-1-(2,2-Dihydroxy-1,3-benzodioxol-5-yl)-3-(3,4-dimethoxy-5-thiophen-2-ylphenyl)prop-2-en-1-one | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_e073a5247b0138724098144fa8f6a473.svg) | 2-Allyl-6,7,8-trimethoxy-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one | IC50 | 780.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_e13a85b9aeed3caf7d5837c9ec961345.svg) | Tert-butyl 2-(2-ethyl-5-methoxy-3-oxo-1-sulfanylideneimidazo[1,5-a]indol-7-yl)oxyacetate | IC50 | 390.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_d5d31f2ffb0fca21799e4fa0a70dd552.svg) | 5,7-Dimethoxy-2-(3-morpholin-4-ylpropyl)-1-sulfanylideneimidazo[1,5-a]indol-3-one | IC50 | 670.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_b8252806d4df3aef3571c51ea182bdbb.svg) | 2-Ethyl-5-methoxy-7-(methoxymethoxy)-1-sulfanylideneimidazo[1,5-a]indol-3-one | IC50 | 280.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_f6a1200e7daed1f6a1ca97ed513299e9.svg) | 2-Ethyl-8-methoxy-6-(pyridin-2-ylmethoxy)-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one | IC50 | 310.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_e0d68c9aef3ff530d9b1a198f19ad61e.svg) | 6,8-Dimethoxy-2-phenethyl-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one | IC50 | 1900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/tumor-necrosis-factor-receptor-r1_ffc4f58b73adc52179d55080bcb29794.svg) | 2-Ethyl-6,8-dimethoxy-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one | IC50 | 1000.0 [1] |