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Tubulin Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Combretastatin A4IC501200.0 [1]
Combretastatin A4Ki3.0 [1], 120.0 [2]
ColchicineIC502900.0 [1]
ColchicineKi2400.0 [1]
PodofiloxIC501700.0 [1]
NocodazoleIC50760.0 [1], 810.0 [2], 1640.0 [3], 1980.0 [4]
VinblastineIC5070.0 [1], 300.0 [2], 2100.0 [3]
ThiocolchicineIC50650.0 [1], 2100.0 [2]
Abt-751IC502400.0 [1], 2880.0 [2]
Abt-751Ki1510.0 [1]
(z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)anilineIC501200.0 [1], 3981.07 [2], 6500.0 [3]
1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)etheneIC501500.0 [1], 2187.76 [2], 2200.0 [3]
Methyl 5-chloro-3-(3,4,5-trimethoxyphenyl)sulfanyl-1H-indole-2-carboxylateIC502500.0 [1]
VinorelbineIC50700.0 [1], 2000.0 [2]
Dolastatin 10IC500.5 [1], 1200.0 [2]
5,3'-Dihydroxy-3,6,7,8,4'-pentamethoxyflavoneIC50830.0 [1]
(Z)-3,5,4'-TrimethoxystilbeneIC503500.0 [1], 3801.89 [2]
Methyl 5-methoxy-3-(3,4,5-trimethoxyphenyl)sulfanyl-1H-indole-2-carboxylateIC502000.0 [1]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[2-(pyridin-3-ylmethylamino)pyridin-3-yl]-1,3,4-oxadiazol-2-amineIC5030.0 [1], 700.0 [2]
N-(1,3-Benzodioxol-5-yl)-5-[2-(pyridin-4-ylmethylamino)pyridin-3-yl]-1,3,4-oxadiazol-2-amineIC5030.0 [1], 1000.0 [2]
2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenolIC5016218.1 [1], 16300.0 [2]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[2-(pyridin-2-ylmethylamino)pyridin-3-yl]-1,3,4-oxadiazol-2-amineIC50190.0 [1], 1900.0 [2]
N-(1,3-Benzodioxol-5-yl)-5-[2-(pyridin-2-ylmethylamino)pyridin-3-yl]-1,3,4-oxadiazol-2-amineIC5030.0 [1], 1700.0 [2]
Boronic acid, trans-6IC501500.0 [1], 22000.0 [2]
[7-(3-Hydroxyprop-1-ynyl)-6-methoxy-2H-indazol-3-yl]-(3,4,5-trimethoxyphenyl)methanoneIC5046.0 [1], 240.0 [2]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[3-(pyridin-2-ylmethylamino)thiophen-2-yl]-1,3,4-oxadiazol-2-amineIC5075.0 [1], 4400.0 [2]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[2-(pyridin-2-ylmethylamino)phenyl]-1,3-oxazol-2-amineIC5010.0 [1], 1400.0 [2]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[2-(pyridin-2-ylmethylamino)phenyl]-1,3,4-oxadiazol-2-amineIC50390.0 [1], 1200.0 [2]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[2-(oxolan-2-ylmethylamino)pyridin-3-yl]-1,3,4-oxadiazol-2-amineIC50390.0 [1], 1700.0 [2]
6-[(Z)-3-(3,4,5-Trimethoxyphenyl)prop-2-enyl]-1-benzothiophen-4-olIC501160.0 [1], 24600.0 [2]
6-[(Z)-3-(3,4,5-Trimethoxyphenyl)prop-2-enyl]-1-benzofuran-4-olIC502500.0 [1], 10300.0 [2]
(E)-1-(6-Methoxy-1,3-benzoxathiol-5-yl)-3-(4-methoxyphenyl)prop-2-en-1-oneIC50489.0 [1], 5800.0 [2]
(E)-1-(5-Methoxy-1,3-benzoxathiol-6-yl)-3-(4-methoxyphenyl)prop-2-en-1-oneIC50108.0 [1], 4150.0 [2]
(5-Ethylpyrido[4,3-b]indol-8-yl)-(4-methylsulfonylphenyl)methanoneIC504300.0 [1]
VincristineIC50500.0 [1]
VincaleukoblastineIC50150.0 [1]
Vinblastine sulfateIC50130.0 [1]
DocetaxelIC50500.0 [1]
Epothilone BIC503.5 [1]
CombretastatinIC505000.0 [1]
EupatilinIC5040000.0 [1]
DeoxypodophyllotoxinIC502400.0 [1]
3,3',4',5,6,7,8-HeptamethoxyflavoneIC5040000.0 [1]
SantinIC505700.0 [1]
CentaureidinIC502000.0 [1]
PectolinarigeninIC5040000.0 [1]
TernatinIC5040000.0 [1]
Dolastatin 15IC5023000.0 [1]
5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavoneIC5040000.0 [1]
2-Phenylquinolin-4-olIC507300.0 [1]
AyaninIC5040000.0 [1]
Curacin AIC50720.0 [1]
Curacin BIC50820.0 [1]
Curacin CIC502300.0 [1]
PhenstatinIC503400.0 [1]
DemethylnobiletinIC5040000.0 [1]
ErianinIC503311.31 [1]
Ustiloxin AIC501100.0 [1]
4'-DemethyldeoxypodophyllotoxinIC502000.0 [1]
VinfosiltineIC50800.0 [1]
Methyl (13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-[[(1R)-1-diethoxyphosphoryl-2-methylpropyl]carbamoyl]-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraene-13-carboxylateIC50400.0 [1]
(3S,10R,13E,16S)-10-[(4-Methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiran-2-yl]ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetroneIC5015000.0 [1]
(E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC5010000.0 [1]
Gardenin AIC5040000.0 [1]
3-(3-Hydroxy-4-methoxyphenyl)-8h-thieno[2,3-b]pyrrolizin-8-oneIC502900.0 [1]
KokusaginineIC50820.0 [1]
Ustiloxin DIC501500.0 [1]
2-(3,4,5-Trimethoxyphenyl)-4H-chromen-4-oneIC5040000.0 [1]
Quercetin 3,4'-dimethyl etherIC503000.0 [1]
2-Amino-7-(dimethylamino)-4-(7-methoxy-1,3-benzodioxol-5-yl)-4H-chromene-3-carbonitrileIC50400.0 [1]
2-Amino-4-(3-bromo-4,5-dimethoxyphenyl)-7-(dimethylamino)-4H-chromene-3-carbonitrileIC508000.0 [1]
3-(3-Hydroxy-4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC501800.0 [1]
2-Styrylquinazolin-4(3H)-oneIC5011000.0 [1]
N-DeacetylthiocolchicineIC501300.0 [1]
(1-Methyl-1H-indol-5-yl)(3,4,5-trimethoxyphenyl)methanoneIC501100.0 [1]
Methanone, (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)-IC507413.1 [1]
2-(3-Methoxyphenyl)-6-pyrrolidin-1-yl-1H-quinolin-4-oneIC50440.0 [1]
2-DemethylthiocolchicineIC502000.0 [1]
CryptophycinIC503700.0 [1]
3-Hydroxy-3',4',5,7-tetramethoxyflavoneIC5040000.0 [1]
5,4'-Dihydroxy-3,6,7,8,3'-pentamethoxyflavoneIC5040000.0 [1]
3-DemethylthiocolchicineIC502000.0 [1]
2-(4-Fluorophenyl)quinazolin-4-olIC5040000000.0 [1]
VintrypolIC50200.0 [1]
1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethyl]benzeneIC507943.28 [1]
Methyl 3-(phenylthio)-1H-indole-2-carboxylateIC508300.0 [1]
2-(4-Methoxyphenyl)-3-(3,4,5-trimethoxybenzoyl)-6-methoxybenzo[b]thiopheneIC5040000.0 [1]
(3,4,5-Trimethoxyphenyl)[2-(3-hydroxy-4-methoxyphenyl)-6-methoxybenzo[b]thiophene-3-yl] ketoneIC503500.0 [1]
3-Hydroxy-2-(2,4,6-trimethoxyphenyl)chromen-4-oneIC5031000.0 [1]
2-(3,4-Dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-oneIC5040000.0 [1]
1H-Indole-2-carboxylic acid, 3-(phenylsulfonyl)-, ethyl esterIC504400.0 [1]
[2-(3-Hydroxy-4-methoxyphenyl)-6-methoxy-1H-indol-3-yl]-(3,4,5-trimethoxyphenyl)methanoneIC501600.0 [1]
(3Z)-6-(4-Hydroxy-3-methoxyphenyl)-3-(1H-pyrrol-2-ylmethylene)-1,3-dihydro-2H-indol-2-oneIC50130.0 [1]
2-(3-Methoxyphenyl)quinazolin-4(3H)-oneIC508600000.0 [1]
(4R)-4-[(1Z,5E,7E,11R)-11-Methoxytetradeca-1,5,7,13-tetraenyl]-2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazoleIC504800.0 [1]
3-(4-Hydroxy-3-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC502600.0 [1]
1H-Indole-2-carboxylic acid, 3-(phenylthio)-, ethyl esterIC504400.0 [1]
2-Methoxy-5-[(alphaS,betaS)-alpha,beta-dihydroxy-3,4,5-trimethoxyphenethyl]phenolIC5022000.0 [1]
Ustiloxin FIC508200.0 [1]
(Z)-1,2,3-Trimethoxy-5-(4-methoxy-3-nitrostyryl)benzeneIC501800.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Tubulin Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/tubulin-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Tubulin Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/tubulin-inhibitors-ic50-ki.
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