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Tubulin beta-1 chain Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Combretastatin A4IC50180.0 [1], 1200.0 [2], 2030.0 [3]
E-Combretastatin A-4IC5033000.0 [1], 50000.0 [2]
[(7S)-7-Acetamido-1,3-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-2-yl] 2-(dimethylamino)acetateIC503800.0 [1], 8700.0 [2]
ColchiceineIC502900.0 [1]
Methanone, (6-methoxy-1H-indol-3-yl)(3,4,5-trimethoxyphenyl)-IC502180.0 [1]
(E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC50620.0 [1]
1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)etheneIC50200.0 [1]
1-(2,5-Dimethoxyphenyl)-3-(4-(dimethylamino)phenyl)-1-methyl-2-propen-1-oneIC5010000.0 [1]
3-(3-Hydroxy-4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC50460.0 [1]
2-DemethylthiocolchicineIC501500.0 [1]
2-DemethylcolchicineIC504800.0 [1]
3',4',5'-Trimethoxy-3,4-dihydroxychalconeIC50100000.0 [1]
(E)-3-(3-Amino-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC502000.0 [1]
(Z)-1,2,3-Trimethoxy-5-(4-methoxy-3-nitrostyryl)benzeneIC502600.0 [1]
(E)-3',4,4',5'-Tetramethoxy-3-fluorochalconeIC501200.0 [1]
2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-phenolIC507200.0 [1]
(Z)-2-Methoxy-5-(3,4,5-trifluorostyryl)phenolIC504500.0 [1]
5-Methoxy-2-methyl-1-(3,4,5-trimethoxybenzoyl)indoleIC503310.0 [1]
(E)-3-(3,5-Difluoro-4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC502400.0 [1]
(E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-oneIC50450.0 [1]
(E)-3-(3-Fluoro-4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC50650.0 [1]
(E)-3-(3,5-Difluoro-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC5012000.0 [1]
(E)-3-(4-Methoxy-3-nitrophenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC5010000.0 [1]
(Z)-3-(3,5-Difluoro-4-methoxyphenyl)-2-methoxy-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC501700.0 [1]
(E)-3-(3-Fluoro-4-methoxyphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-oneIC507900.0 [1]
(Z)-3-(3-Fluoro-4-methoxyphenyl)-2-methoxy-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC50470.0 [1]
3-(3-Hydroxy-4-methoxy-phenyl)-2-methyl-1-(3,4,5-trimethoxy-phenyl)-propan-1-oneIC504000.0 [1]
(E)-3-(3,5-Difluoro-4-methoxyphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-oneIC5031000.0 [1]
(Z)-3-(3-Hydroxy-4-methoxyphenyl)-2-methoxy-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC50510.0 [1]
5-[(E)-3-Hydroxy-2-methyl-3-(3,4,5-trimethoxy-phenyl)-propenyl]-2-methoxy-phenolIC5010000.0 [1]
2-Methoxy-5-(3,4,5-trimethoxyanilino)phenolIC50100000.0 [1]
5-Methoxy-1-(3,4,5-trimethoxybenzoyl)indoleIC503760.0 [1]
1,2,3-Trimethoxy-5-[(E)-2-(3-bromo-4-methoxyphenyl)vinyl]benzeneIC5031000.0 [1]
(E)-3',4,5'-Trimethoxystilbene-3,4'-diolIC5014000.0 [1]
5-[(Z)-2-(3,4,5-Trimethylphenyl)vinyl]-2-methoxyphenolIC50120.0 [1]
2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldehydeIC50560.0 [1]
2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenolIC5021000.0 [1]
2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenolIC5011000.0 [1]
3-[2-Methoxy-5-[(3,4,5-trimethoxyphenoxy)methyl]phenoxy]propane-1,2-diolIC50100000.0 [1]
[2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenyl]-methanolIC50100000.0 [1]
[2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-phenoxy]-acetaldehydeIC5041000.0 [1]
(Z)-3,4,5-Trimethoxy-4'-ethylstilbeneIC503400.0 [1]
6-Methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)-1H-indoleIC50900.0 [1]
5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-1,2,3-trimethyl-benzeneIC50700.0 [1]
1,2,3-Trimethoxy-5-[(Z)-2-(3,4-dimethylphenyl)vinyl]benzeneIC502000.0 [1]
4-[(Z)-2-(3-Fluoro-4-methoxyphenyl)ethenyl]-1,2-dimethylbenzeneIC506600.0 [1]
1,2,3-Trimethoxy-5-[(Z)-2-(3-bromo-4-methoxyphenyl)vinyl]benzeneIC501100.0 [1]
1,2,3-Triethoxy-5-[(Z)-2-(3-fluoro-4-methoxyphenyl)vinyl]benzeneIC501200.0 [1]
5-[(Z)-2-(4-Methoxy-phenyl)-vinyl]-1,2,3-trimethyl-benzeneIC50650.0 [1]
5-[(Z)-2-(3,4-Dimethyl-phenyl)-vinyl]-2-methoxy-phenolIC503100.0 [1]
2-Methoxy-5-[(Z)-2-(3,4,5-triethoxy-phenyl)-vinyl]-phenolIC50500.0 [1]
(3,5-Dimethoxy-phenyl)-(6-methoxy-1H-indol-3-yl)-methanoneIC502690.0 [1]
5-[(Z)-2-[3-(2-Chloroethoxy)-4-methoxyphenyl]ethenyl]-1,2,3-trimethoxybenzeneIC5040000.0 [1]
3-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]propan-1-olIC506500.0 [1]
1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-1-methyl-vinyl]-benzeneIC501300.0 [1]
[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] N,N-bis(2-chloroethyl)carbamateIC5040000.0 [1]
2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)but-1-enyl]phenolIC50130.0 [1]
2-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]ethanolIC502800.0 [1]
2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-propenyl]-phenolIC50130.0 [1]
2-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]ethyl methanesulfonateIC5040000.0 [1]
1,2,3-Trifluoro-5-[(Z)-2-(3-fluoro-4-methoxy-phenyl)-vinyl]-benzeneIC505500.0 [1]
[(7S)-7-Acetamido-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-2-yl] 2-(dimethylamino)acetateIC5015000.0 [1]
[(7S)-7-Acetamido-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-2-yl] 2-(dimethylamino)acetate;2,3-dihydroxybutanedioic acidIC5013000.0 [1]
5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-2,3-dimethoxy-phenolIC501250.0 [1]
2-Methoxy-5-[(E)-1-(3,4,5-trimethoxyphenyl)prop-1-en-2-yl]phenolIC509000.0 [1]
(E)-3-(3,4,5-Trihydroxyphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-oneIC50100000.0 [1]
2-Methoxy-5-((Z)-styryl)-phenolIC502500.0 [1]
1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-piperidine; hydrochlorideIC5040000.0 [1]
1-[2-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]ethyl]imidazoleIC507600.0 [1]
4-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-morpholine; hydrochlorideIC5040000.0 [1]
1-[2-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]ethyl]-4-methylpiperazineIC5040000.0 [1]
2-[2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]-N,N-dimethylethanamineIC5040000.0 [1]
1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-pyrrolidine; hydrochlorideIC5040000.0 [1]
Diethyl-(2-{2-methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-amine; hydrochlorideIC5040000.0 [1]
1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-1H-pyrrole; hydrochlorideIC5020000.0 [1]
Items per page: 1 - 10 of 75
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References

This online tool may be cited as follows

MLA

"Quest Database™ Tubulin beta-1 chain Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/tubulin-beta-1-chain-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Tubulin beta-1 chain Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/tubulin-beta-1-chain-inhibitors-ic50-ki.
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