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Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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N'-(3,4-Dimethoxybenzylidene)-2-(phenylsulfanyl)acetohydrazideIC50660.0 [1]
(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-1,5-naphthyridin-2-ylmethylideneamino]cyclopropane-1-carboxamideIC5050000.0 [1]
(1R,2R)-N-[(E)-[3-Methoxy-4-(pyridin-3-ylmethoxy)phenyl]methylideneamino]-2-phenylcyclopropane-1-carboxamideIC501600.0 [1]
(1R,2R)-2-(6-Methoxypyridin-3-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC505000.0 [1]
(1R,2R)-2-(5-Chloropyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC505400.0 [1]
(1R,2R)-2-(6-Methoxypyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC50410.0 [1]
(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamideIC5037.0 [1]
(1R,2R)-2-(4-Fluorophenyl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC50510.0 [1]
(1R,2R)-N-[(E)-(8-Methoxyquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamideIC5090.0 [1]
(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-chloroquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC50650.0 [1]
(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC50800.0 [1]
(1S,2S)-N-[(E)-(8-Methylquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamideIC50240.0 [1]
(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-N-methyl-2-phenylcyclopropane-1-carboxamideIC505000.0 [1]
(1R,2R)-N-[(E)-(8-Chloroquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamideIC50340.0 [1]
(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-methoxyquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamideIC5045.0 [1]
(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-(6-methylpyridin-2-yl)cyclopropane-1-carboxamideIC503200.0 [1]
(1R,2R)-N-[(E)-(8-Fluoroquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamideIC50550.0 [1]
(1R,2R)-2-Phenyl-N-[(E)-[8-(trifluoromethyl)quinolin-6-yl]methylideneamino]cyclopropane-1-carboxamideIC5010000.0 [1]
(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-quinolin-2-ylcyclopropane-1-carboxamideIC50610.0 [1]
2-(3-Chlorophenyl)sulfanyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamideIC5055.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamideIC5030.0 [1]
1-[2-(4-Chlorophenyl)ethyl]-3-[(E)-(3,4-dimethoxyphenyl)methylideneamino]ureaIC5051.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-(2-methylquinolin-6-yl)methylideneamino]propanamideIC5030000.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-quinolin-7-ylmethylideneamino]propanamideIC5030000.0 [1]
2-(3-Chlorophenyl)sulfanyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]acetamideIC5040.0 [1]
N-[(E)-3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylideneamino]-3-(3,4-dimethylindol-1-yl)propanamideIC5024.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(1,7-dimethylindol-3-yl)propanamideIC509.0 [1]
3-[4-Chloro-3-[(dimethylamino)methyl]indol-1-yl]-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamideIC501500.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methoxy-3-methylindol-1-yl)propanamideIC506.0 [1]
2-(3-Chlorophenyl)sulfonyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamideIC501700.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-[4-(hydroxymethyl)-3-methylindol-1-yl]propanamideIC50260.0 [1]
3-(3-Chloro-4-methylindol-1-yl)-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamideIC501.3 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-indol-1-ylpropanamideIC50170.0 [1]
2-(3-Chlorophenyl)sulfanyl-N-[(E)-(4,5-dimethoxypyridin-2-yl)methylideneamino]propanamideIC5030000.0 [1]
N-[(E)-(2-Methoxy-4-methylquinolin-6-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamideIC502000.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methylindol-1-yl)propanamideIC5012.0 [1]
N-[(E)-3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylideneamino]-3-(3-methylindol-1-yl)propanamideIC50180.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-quinolin-6-ylmethylideneamino]propanamideIC50340.0 [1]
N-[(E)-(4-Methyl-2,3-dihydro-1,4-benzoxazin-7-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamideIC50750.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamideIC505.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-[3-(hydroxymethyl)phenyl]sulfanylacetamideIC5030000.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-(4-methylquinolin-6-yl)methylideneamino]propanamideIC50370.0 [1]
1-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(2-phenylethyl)ureaIC50200.0 [1]
N-[(E)-(4-Methoxyquinolin-6-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamideIC50120.0 [1]
N-[(E)-(3-Chloro-4,5-dimethoxyphenyl)methylideneamino]-3-(3,4-dimethylindol-1-yl)propanamideIC5038.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3-methylpyrrolo[2,3-b]pyridin-1-yl)propanamideIC50680.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-3-ylmethoxy)phenyl]methylideneamino]propanamideIC5053.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridazin-3-ylmethoxy)phenyl]methylideneamino]propanamideIC50180.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-4-ylmethoxy)phenyl]methylideneamino]propanamideIC5046.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-quinolin-3-ylpropanamideIC50810.0 [1]
2-(3-Chlorophenyl)sulfanyl-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]acetamideIC50830.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamideIC502200.0 [1]
3-(6-Methoxypyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamideIC502000.0 [1]
3-(1-Methylindol-3-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamideIC50160.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyrazin-2-ylmethoxy)phenyl]methylideneamino]propanamideIC5060.0 [1]
N-[(E)-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]methylideneamino]-3-(3-methylindol-1-yl)propanamideIC50500.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(1-methylindol-3-yl)propanamideIC5051.0 [1]
(1R,2R)-N-[(E)-(8-Methylquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamideIC50420.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-(8-methoxyquinolin-6-yl)methylideneamino]propanamideIC501.4 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-(3-methoxy-4-phenylmethoxyphenyl)methylideneamino]propanamideIC5080.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-1,5-naphthyridin-2-ylmethylideneamino]propanamideIC501300.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-(3-methylquinolin-6-yl)methylideneamino]propanamideIC50210.0 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-2-ylmethoxy)phenyl]methylideneamino]propanamideIC5066.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3-methylindol-1-yl)propanamideIC5017.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methylbenzimidazol-1-yl)propanamideIC502400.0 [1]
3-(3-Methylindol-1-yl)-N-[(E)-pyrido[3,2-c]pyridazin-6-ylmethylideneamino]propanamideIC50430.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3,4-dimethylindol-1-yl)propanamideIC501.8 [1]
3-(3,4-Dimethylindol-1-yl)-N-[(E)-(2-fluoro-4,5-dimethoxyphenyl)methylideneamino]propanamideIC503.0 [1]
4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamideIC5039810.72 [1]
Items per page: 1 - 10 of 69
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References

This online tool may be cited as follows

MLA

"Quest Database™ Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/transient-receptor-potential-cation-channel-subfamily-m-member-5-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 20). Quest Database™ Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/transient-receptor-potential-cation-channel-subfamily-m-member-5-inhibitors-ic50-ki.
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