![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_dfbcb03106a2cbe9a180d4132a0fa882.svg) | Liothyronine | IC50 | 0.26 [1], 2.9 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_dfbcb03106a2cbe9a180d4132a0fa882.svg) | Liothyronine | Ki | 0.08 [1], 0.55 [2], 0.68 [3], 2.29 [4] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_da535583fefa21c61a60e05be3979fda.svg) | {3,5-Dichloro-4-[4-Hydroxy-3-(Propan-2-Yl)phenoxy]phenyl}acetic Acid | IC50 | 1.1 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_da535583fefa21c61a60e05be3979fda.svg) | {3,5-Dichloro-4-[4-Hydroxy-3-(Propan-2-Yl)phenoxy]phenyl}acetic Acid | Ki | 0.24 [1], 0.37 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_040690236c3e509cadd4836a14b9303f.svg) | 2-Methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran | IC50 | 4100.0 [1], 5100.0 [2], 5128.61 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_101fd9c2e5ddc96b94358209a7b6224b.svg) | 3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenylacetic acid | IC50 | 0.1 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_74b1a69418d619ad23467b0613e4ce5d.svg) | 3,5-Dibromo-4-[4-hydroxy-3,5-bis(propan-2-yl)phenoxy]benzoic acid | IC50 | 910.0 [1], 912.01 [2], 4500.0 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_e337f6a29529fe7264347c7a7b7df354.svg) | 2-[3,5-Dibromo-4-(hexyloxy)phenyl]acetic acid | IC50 | 800.0 [1], 1500.0 [2], 1513.56 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_240c42e6245a9bd5c4b457bee6077c8d.svg) | 3-[3,5-Dibromo-4-(hexyloxy)phenyl]propanoic acid | IC50 | 360.0 [1], 363.08 [2], 1000.0 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_913f29d3afad7aabf69b135b0d9f4841.svg) | 2-[3,5-Dibromo-4-(2-ethylbutoxy)phenyl]acetic Acid | IC50 | 700.0 [1], 794.33 [2], 800.0 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_9c92aab59025b827a4343d876f98c707.svg) | Tiratricol | IC50 | 0.04 [1], 0.05 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_ec055aad0e3524af51cdc39f2b92f38c.svg) | Thyropropic acid | IC50 | 0.02 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_47cb0f1dc60a8810731cb09cf28e9d96.svg) | 3,5-Dibromo-4-(3-Isopropyl-Phenoxy)benzoic Acid | IC50 | 0.03 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_30dc0a1a36786374d8f9c0073f70baa4.svg) | 2-[4-(3-Bromo-4-propanamidophenoxy)-3,5-dichlorophenyl]acetic acid | IC50 | 140.0 [1], 141.25 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5ce4722fe740ffe8f3d3840f943053fe.svg) | 2-{4-[3-Bromo-4-(2-ethylbutanamido)phenoxy]-3,5-dichlorophenyl}acetic acid | IC50 | 15.85 [1], 16.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_e933dc9396105e3ccad05e84450b5785.svg) | 3-{3,5-Dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}propanoic acid | IC50 | 0.15 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_e6c583307100f77ce44f3f52a50ab058.svg) | 2-[3,5-Dibromo-4-(3-methylbutoxy)phenyl]acetic Acid | IC50 | 1819.7 [1], 18000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_39c74729bb2dee1a609ba83574aff65b.svg) | 3-[3,5-Dibromo-4-(2-ethylbutoxy)phenyl]propanoic Acid | IC50 | 810.0 [1], 812.83 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_af89fc3c451e269ccf4e7bb3ae2f091c.svg) | 2-[3,5-Dibromo-4-(pentyloxy)phenyl]acetic acid | IC50 | 5700.0 [1], 5754.4 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_d459d0cff9a5f0bdf244f1bac9cf56d7.svg) | 3-[3,5-Dibromo-4-(3-methylbutoxy)phenyl]propanoic Acid | IC50 | 1800.0 [1], 1819.7 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_6b8075827a7e7b2472583164c6944256.svg) | 2-{4-[3-Bromo-4-(2-methylpentanamido)phenoxy]-3,5-dichlorophenyl}acetic acid | IC50 | 46.77 [1], 47.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4d28c173b6b286b241afebfda47b2ef0.svg) | 2-{4-[3-Bromo-4-(2-propylpentanamido)phenoxy]-3,5-dichlorophenyl}acetic acid | IC50 | 44.67 [1], 45.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_50951f737650c3b365d666d71a5104ed.svg) | Detrothyronine | IC50 | 0.26 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_569c8b1bc9bba6ea163b36bf6e39b360.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(piperidine-1-carbonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | IC50 | 5.25 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_569c8b1bc9bba6ea163b36bf6e39b360.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(piperidine-1-carbonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | Ki | 0.63 [1], 1.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_096d6c682d9c50c70b4854f72a0068cb.svg) | 3,5-Dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]benzoic acid | IC50 | 20.89 [1], 21.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_888ede510643a05b030275cd4e9f336f.svg) | 2-(3,5-Dibromo-4-butoxyphenyl)acetic acid | IC50 | 1900.0 [1], 1905.46 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_9d57257dbfdb27f865d9319812642d4c.svg) | 3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)benzoic acid | IC50 | 2.09 [1], 2.1 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_18bb3db90a845fd99ae17da46e0caef9.svg) | 3,5-Dichloro-4-(3-bromo-4-isobutyramidophenoxy)phenylacetic acid | IC50 | 18.0 [1], 18.2 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_e0b0be8bbc147ba092b34f4f6cf4fa2f.svg) | 4,6-Dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-indole-2-carboxylic acid | IC50 | 0.06 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_e0b0be8bbc147ba092b34f4f6cf4fa2f.svg) | 4,6-Dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-indole-2-carboxylic acid | Ki | 0.06 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_1f7591f823026ccd6795361773f1f47e.svg) | 2-[3,5-Dibromo-4-(cyclohexylmethoxy)phenyl]acetic Acid | IC50 | 520.0 [1], 770.0 [2], 776.25 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_d5737c9009dc496834af2ece005e0f70.svg) | 3-[3,5-Dibromo-4-(cyclohexylmethoxy)phenyl]propanoic Acid | IC50 | 120.0 [1], 190.0 [2], 190.55 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_f0f6da90e085a7471b6a66dcab2e2e40.svg) | (2-Butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethyl]-3,5-diiodophenyl]methanone | IC50 | 600.0 [1], 602.56 [2], 10000.0 [3] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_3f05ea42875ad24728647908c4ea619b.svg) | Phosphonic acid, p-((4-((4-hydroxy-3-(1-methylethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)- | Ki | 2.17 [1], 2.95 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_30e8d1298282ca80195aaa20517f0cb4.svg) | 2-[3,5-Dichloro-4-(4-hydroxy-3-phenylphenoxy)phenyl]acetic acid | IC50 | 2.88 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_38952384ef0b0f06a431827de093989f.svg) | 2-(3,5-Dibromo-4-{4-hydroxy-3-[(2-phenylethyl)carbamoyl]phenoxy}phenyl)acetic acid | IC50 | 0.62 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_2efe5e324d4cebbb907ddc080de30f89.svg) | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzamide | IC50 | 0.2 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_2efe5e324d4cebbb907ddc080de30f89.svg) | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzamide | Ki | 0.07 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_7f88c30990f0b4973ff84ce8237d5d7e.svg) | 4,6-Dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-indole-2-carboxylic acid | IC50 | 0.28 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_f660066bb763d1c2fe37215446067bb3.svg) | 3,5-Dibromo-4-ethoxyphenylacetic acid | IC50 | 32000.0 [1], 32359.37 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_396eebf6e4795090dee03a1da8daa369.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(pyridin-2-yl)phenoxy]phenyl}acetic acid | IC50 | 138.04 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_49b3078bed0cac72f18f580897ab3db3.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(pyridin-4-yl)phenoxy]phenyl}acetic acid | IC50 | 123.03 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0933c6544fee423437c8c06be0b47e84.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(1,3-thiazol-2-yl)phenoxy]phenyl}acetic acid | IC50 | 28.18 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4bfbf7974744b10f1a517db64f082791.svg) | 5-[2,6-Dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxy-N-phenylbenzenesulfonamide | IC50 | 0.28 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4bfbf7974744b10f1a517db64f082791.svg) | 5-[2,6-Dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxy-N-phenylbenzenesulfonamide | Ki | 0.1 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5fdd5f0ebee2519ce5cb3de82fedd7a5.svg) | 5-[2,6-Dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-N-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)-2-hydroxybenzamide | IC50 | 0.17 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5fdd5f0ebee2519ce5cb3de82fedd7a5.svg) | 5-[2,6-Dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-N-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)-2-hydroxybenzamide | Ki | 0.06 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_b98cd3b811cadbd8ce12692b7c9404cb.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(morpholine-4-carbonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | IC50 | 2.0 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_b98cd3b811cadbd8ce12692b7c9404cb.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(morpholine-4-carbonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | Ki | 0.72 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_73a6f00023caef03190be8bf7ce5d57d.svg) | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzamide | IC50 | 1.78 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_73a6f00023caef03190be8bf7ce5d57d.svg) | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzamide | Ki | 0.64 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4d79788a2a5f706540aee414b19bc3f3.svg) | 2-[3-Chloro-4-(4-hydroxy-3-piperidin-1-ylsulfonylphenoxy)-5-methylphenyl]-1,2,4-triazine-3,5-dione | IC50 | 0.36 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4d79788a2a5f706540aee414b19bc3f3.svg) | 2-[3-Chloro-4-(4-hydroxy-3-piperidin-1-ylsulfonylphenoxy)-5-methylphenyl]-1,2,4-triazine-3,5-dione | Ki | 0.13 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_83d85a78dc1b8c381c32eceb9c6c4d70.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(piperidine-1-sulfonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | IC50 | 0.06 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_83d85a78dc1b8c381c32eceb9c6c4d70.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(piperidine-1-sulfonyl)-phenoxy]-phenyl}-2H-[1,2,4]triazine-3,5-dione | Ki | 0.02 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0874f3b543ff87ab5ee831ff3e6b92f2.svg) | 2-[3-Chloro-4-(4-hydroxy-3-morpholin-4-ylsulfonylphenoxy)-5-methylphenyl]-1,2,4-triazine-3,5-dione | IC50 | 75.86 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0874f3b543ff87ab5ee831ff3e6b92f2.svg) | 2-[3-Chloro-4-(4-hydroxy-3-morpholin-4-ylsulfonylphenoxy)-5-methylphenyl]-1,2,4-triazine-3,5-dione | Ki | 27.0 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_24f01f815bb6cac3ffdfcc0958890b3f.svg) | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzenesulfonamide | IC50 | 1.12 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_24f01f815bb6cac3ffdfcc0958890b3f.svg) | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzenesulfonamide | Ki | 0.4 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_be2aa943261d0172394ceb4b2adaf1de.svg) | 2-{4-[4-Hydroxy-3-(piperidine-1-sulfonyl)-phenoxy]-3,5-dimethyl-phenyl}-2H-[1,2,4]triazine-3,5-dione | IC50 | 1.29 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_be2aa943261d0172394ceb4b2adaf1de.svg) | 2-{4-[4-Hydroxy-3-(piperidine-1-sulfonyl)-phenoxy]-3,5-dimethyl-phenyl}-2H-[1,2,4]triazine-3,5-dione | Ki | 0.46 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5d07c2e9cacd27f5077e6b5c473d235f.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(pyrimidin-5-yl)phenoxy]phenyl}acetic acid | IC50 | 67.61 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_d5331c10b471aff1fef19ff32fa0d27d.svg) | (2R)-2-Amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenoxy]-3,5-diiodophenyl}propanoic acid | IC50 | 0.11 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_59b6a9858e0ceea7c9e69d3af6d9665c.svg) | 2-{4-[3-Bromo-4-(2-methylbutanamido)phenoxy]-3,5-dichlorophenyl}acetic acid | IC50 | 4.27 [1], 4.3 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_328b026701ed657aeca67f176824fc72.svg) | 2-(3,5-Dichloro-4-{4-hydroxy-3-[3-(trifluoromethyl)phenyl]phenoxy}phenyl)acetic acid | IC50 | 0.85 [1], 0.93 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_a5cff70e4cdcad9e1ee8194954464424.svg) | 2-(3,5-Dichloro-4-{4-hydroxy-3-[3-(propan-2-yl)phenyl]phenoxy}phenyl)acetic acid | IC50 | 3.98 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0319b2c57cdee29b5e7299a5ae74362b.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phenoxy]phenyl}acetic acid | IC50 | 20.89 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4c7545fd6870e956312602ad36ed94aa.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)phenoxy]phenyl}acetic acid | IC50 | 10.96 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_d4a00252b1fd2822ca2a6b544a17bfcf.svg) | 2-(3,5-Dichloro-4-{3-[3-(difluoromethoxy)phenyl]-4-hydroxyphenoxy}phenyl)acetic acid | IC50 | 0.78 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_8dd59d072c9ccaecafa0b9348ad5f992.svg) | 2-(3,5-Dichloro-4-{4-hydroxy-3-[3-(trifluoromethoxy)phenyl]phenoxy}phenyl)acetic acid | IC50 | 3.39 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_7ea29b7c8c10c64fedc1c7a7d9b0972b.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)phenoxy]phenyl}acetic acid | IC50 | 50.12 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_1a4f22f30e2cf90cd7e2f13fff41ebfc.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(3-hydroxyphenyl)phenoxy]phenyl}acetic acid | IC50 | 75.86 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5b6a2ce5a6fe14ce43401dc8052d03ee.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(4-hydroxyphenyl)phenoxy]phenyl}acetic acid | IC50 | 87.1 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_ea3536df01f0661470284a089cec8bff.svg) | 2-{3,5-Dichloro-4-[4-hydroxy-3-(pyridin-3-yl)phenoxy]phenyl}acetic acid | IC50 | 40.74 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_dee41166e2503885d696f98cc916f8d3.svg) | 2-[3,5-Dibromo-4-(4-hydroxy-3-phenoxyphenoxy)phenyl]acetic acid | IC50 | 6.03 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_aa537f79b5b6cb785e42a7d5bbfa09c5.svg) | 2-(3,5-Dibromo-4-{4-hydroxy-3-[2-(trifluoromethyl)phenoxy]phenoxy}phenyl)acetic acid | IC50 | 7.59 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_ff8cafd12e9f57833f462923c356ded5.svg) | 2-(3,5-Dibromo-4-{4-hydroxy-3-[3-(trifluoromethyl)phenoxy]phenoxy}phenyl)acetic acid | IC50 | 1.1 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_01b24415ae462686d582e3759866413d.svg) | 2-{3,5-Dibromo-4-[4-hydroxy-3-(3-phenylphenoxy)phenoxy]phenyl}acetic acid | IC50 | 60.26 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_b943ba8238e6fab3889ab52c8580f755.svg) | 2-{3,5-Dibromo-4-[4-hydroxy-3-(2-hydroxyphenoxy)phenoxy]phenyl}acetic acid | IC50 | 83.18 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_3adc1169adcd9d6ed2872131943b192b.svg) | 2-{3,5-Dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)phenoxy]phenyl}acetic acid | IC50 | 46.77 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_436241f714ca589ec93a7d678473d6af.svg) | 2-{3,5-Dibromo-4-[4-hydroxy-3-(4-hydroxyphenoxy)phenoxy]phenyl}acetic acid | IC50 | 6.03 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_ba246aca29ffd94b6e053ea075b33bb8.svg) | 2-{3,5-Dibromo-4-[4-hydroxy-3-(phenylcarbamoyl)phenoxy]phenyl}acetic acid | IC50 | 34.67 [1], 35.48 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_dc0d397a3e4fe2cae39e4dfd253fa5fd.svg) | 2-(3,5-Dibromo-4-{4-hydroxy-3-[(3-phenylpropyl)carbamoyl]phenoxy}phenyl)acetic acid | IC50 | 6.76 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0ec50d649abf723133d24035f14b204d.svg) | 2-(3,5-Dibromo-4-{4-hydroxy-3-[(4-phenylbutyl)carbamoyl]phenoxy}phenyl)acetic acid | IC50 | 18.2 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_6ad6e847593e9db435326f4d67256af1.svg) | 2-[3,5-Dibromo-4-(4-hydroxy-3-{[2-(4-methoxyphenyl)ethyl]carbamoyl}phenoxy)phenyl]acetic acid | IC50 | 4.79 [1], 37.15 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5a3d739a5dc580307bada0ca6f365501.svg) | 2-[3,5-Dibromo-4-(4-hydroxy-3-{[2-(3-methoxyphenyl)ethyl]carbamoyl}phenoxy)phenyl]acetic acid | IC50 | 4.9 [1], 8.51 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_a1b9312a85a38ae7a0592aadab1828ba.svg) | 2-[3,5-Dibromo-4-(4-hydroxy-3-{[2-(2-methoxyphenyl)ethyl]carbamoyl}phenoxy)phenyl]acetic acid | IC50 | 0.47 [1], 8.51 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_dfe9e6a80c6b02c365841b8c8705f2d4.svg) | 2-(3,5-Dibromo-4-{3-[(2,2-diphenylethyl)carbamoyl]-4-hydroxyphenoxy}phenyl)acetic acid | IC50 | 0.47 [1], 37.15 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_ad1239d46722c77d44e6bb9644009861.svg) | 2-[3,5-Dibromo-4-(4-hydroxy-3-{[2-(pyridin-2-yl)ethyl]carbamoyl}phenoxy)phenyl]acetic acid | IC50 | 67.61 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0dc7e8ed072f86e70c6e8e4541fa5b6e.svg) | 2-[3,5-Dichloro-4-(4-hydroxy-3-spiro[8-azabicyclo[3.2.1]octane-3,2'-oxolane]-8-ylsulfonylphenoxy)phenyl]-1,2,4-triazine-3,5-dione | IC50 | 0.78 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_0dc7e8ed072f86e70c6e8e4541fa5b6e.svg) | 2-[3,5-Dichloro-4-(4-hydroxy-3-spiro[8-azabicyclo[3.2.1]octane-3,2'-oxolane]-8-ylsulfonylphenoxy)phenyl]-1,2,4-triazine-3,5-dione | Ki | 0.28 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4bdd770d2c51769c3d61d7cda5196cec.svg) | 2-[3,5-Dichloro-4-(4-hydroxy-3-spiro[1,3-dioxolane-2,3'-8-azabicyclo[3.2.1]octane]-8'-ylsulfonylphenoxy)phenyl]-1,2,4-triazine-3,5-dione | IC50 | 0.87 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4bdd770d2c51769c3d61d7cda5196cec.svg) | 2-[3,5-Dichloro-4-(4-hydroxy-3-spiro[1,3-dioxolane-2,3'-8-azabicyclo[3.2.1]octane]-8'-ylsulfonylphenoxy)phenyl]-1,2,4-triazine-3,5-dione | Ki | 0.31 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_6e9d709d8b013bb10aab1998da99c632.svg) | 6-(4-Hydroxy-3-isopropylphenoxy)-5,7-dimethylquinoline-2-carboxylic acid | IC50 | 15.0 [1], 15.14 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_5e44a8149bdb78ce465e1d9a0952e15b.svg) | 5,7-Dibromo-6-(4-hydroxy-3-propan-2-ylphenoxy)-4-oxo-1H-quinoline-2-carboxylic acid | IC50 | 51.0 [1], 51.29 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4db192e08cae1237bb8d7b66e014b8a6.svg) | 5,7-Dichloro-6-(4-hydroxy-3-propan-2-ylphenoxy)-4-oxo-1H-quinoline-2-carboxylic acid | IC50 | 15.14 [1], 870.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_4a8f40cbed8c822c693e4b0abe2c698c.svg) | 6-(4-Hydroxy-3-propan-2-ylphenoxy)-5,7-dimethyl-4-oxo-1H-quinoline-2-carboxylic acid | IC50 | 239.88 [1], 240.0 [2] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_a45b9bb1a8daa0d3fc2aa42aea1cd332.svg) | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzenesulfonamide | IC50 | 1.29 [1] |
![](https://images.aatbio.com/dataset/ic50/thyroid-hormone-receptor-beta-1_a45b9bb1a8daa0d3fc2aa42aea1cd332.svg) | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenoxy]-2-hydroxybenzenesulfonamide | Ki | 0.46 [1] |