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Threonyl-tRNA synthetase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
5'-O-(N-(L-Threonyl)-sulfamoyl)adenosineIC5015.0 [1]
(2S,3R)-2-Amino-3-hydroxy-N-(4-phenoxyphenyl)sulfonylbutanamideKi36800.0 [1]
(2S,3R)-2-Amino-N-[[3-(4-amino-2-chloroquinazolin-7-yl)phenyl]methyl]-3-hydroxybutanamideKi935.0 [1]
(2S,3R)-2-Amino-N'-[3-(4-amino-2-chloroquinazolin-7-yl)phenyl]-3-hydroxybutanehydrazideKi399.0 [1]
3-(4-Amino-2-chloroquinazolin-7-yl)-N-[(2R,3R)-2-amino-3-hydroxybutyl]benzenesulfonamideKi50000.0 [1]
(2S,3R)-2-Amino-3-hydroxy-N-methyl-N-[3-(1-oxo-2,3-dihydroisoindol-5-yl)phenyl]sulfonylbutanamideKi50000.0 [1]
(2S,3R)-2-Amino-N-[(E)-2-[3-(6-aminopyrimidin-4-yl)phenyl]ethenyl]sulfonyl-3-hydroxypentanamideKi32.0 [1]
(2S,3R)-2-Amino-N-[(E)-2-[3-(6-aminopyrimidin-4-yl)phenyl]ethenyl]sulfonyl-3-hydroxy-4-methylpentanamideKi601.0 [1]
(2S,3R)-N-[(E)-2-[3-(6-Aminopyrimidin-4-yl)phenyl]ethenyl]sulfonyl-2,3-dihydroxybutanamideKi50000.0 [1]
(2S,3R)-2,3-Diamino-N-[(E)-2-[3-(6-aminopyrimidin-4-yl)phenyl]ethenyl]sulfonylbutanamideKi12576.0 [1]
N-{[3-(4-Aminoquinazolin-7-Yl)phenyl]sulfonyl}-L-ThreoninamideKi3.3 [1]
(2S,3R)-2-Amino-N-[3-(2,4-diaminoquinazolin-7-yl)phenyl]sulfonyl-3-hydroxybutanamideKi10.1 [1]
N-{[3-(4-Amino-2-Chloroquinazolin-7-Yl)phenyl]sulfonyl}-L-ThreoninamideKi1.2 [1]
N-{[3-(4-Amino-2-Methylquinazolin-7-Yl)phenyl]sulfonyl}-L-ThreoninamideKi72.0 [1]
(2S,3R)-2-Amino-N-[3-(1-amino-3-chloroisoquinolin-6-yl)phenyl]sulfonyl-3-hydroxybutanamideKi463.0 [1]
(2S,3R)-2-Amino-N-[3-(1-aminoisoquinolin-6-yl)phenyl]sulfonyl-3-hydroxybutanamideKi2242.0 [1]
(2S,3R)-2-Amino-N-[7-(6-aminopyrimidin-4-yl)naphthalen-2-yl]sulfonyl-3-hydroxybutanamideKi3.0 [1]
(2S,3R)-2-Amino-N-[(E)-2-[3-(6-aminopyrimidin-4-yl)phenyl]ethenyl]sulfonyl-3-hydroxybutanamideKi4.1 [1]
(2S,3R)-2-Amino-3-hydroxy-N-[7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)naphthalen-2-yl]sulfonylbutanamideKi1.8 [1]
(2S,3R)-2-Amino-3-hydroxy-N-[[7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3,4-dihydro-1H-isoquinolin-2-yl]sulfonyl]butanamideKi5.2 [1]
(2S,3R)-2-Amino-3-hydroxy-N-[3-(1-oxo-2,3-dihydroisoindol-5-yl)phenyl]sulfonylbutanamideKi91.0 [1]
(2S,3R)-2-Amino-N-[3-(3-chloro-2H-indazol-5-yl)phenyl]sulfonyl-3-hydroxybutanamideKi1518.0 [1]
(2S,3R)-2-Amino-3-hydroxy-N-[3-(3-methyl-2H-indazol-5-yl)phenyl]sulfonylbutanamideKi5820.0 [1]
N-{[3-(2h-Indazol-5-Yl)phenyl]sulfonyl}-L-ThreoninamideKi50000.0 [1]
[(2S,3R,4S,5S)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-[(2S,3R)-2-amino-3-hydroxybutanoyl]sulfamateKi13.4 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Threonyl-tRNA synthetase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/threonyl-trna-synthetase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Threonyl-tRNA synthetase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/threonyl-trna-synthetase-inhibitors-ic50-ki.
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