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Terminal deoxynucleotidyltransferase Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
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▼
Standard Values (in nM)
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▼
Ethyl (E)-6-[4-(4-cyanobenzoyl)-1H-pyrrol-2-yl]-2,4-dioxohex-5-enoateKi1500.0 [1], 1700.0 [2]
(E)-6-[4-(2-Fluorobenzoyl)-1H-pyrrol-2-yl]-2,4-dioxohex-5-enoic acidKi400.0 [1], 500.0 [2]
(E)-6-[1-[(4-Hydroxyphenyl)methyl]indol-3-yl]-2,4-dioxohex-5-enoic acidKi450.0 [1], 500.0 [2]
Untenone AIC5016000.0 [1]
(1S,2S)-2-Hexadecyl-2-methoxymethoxy-5-oxo-cyclopent-3-enecarboxylic acid methyl esterIC5018000.0 [1]
(3As,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycarbonyl)-3-oxo-3a,4,7,7a-tetrahydroindene-4-carboxylic acidIC502500.0 [1]
(3As,4S,7R,7aR)-1,6-diethyl-2,7-bis(methoxycarbonyl)-3-oxo-3a,4,7,7a-tetrahydroindene-4-carboxylic acidIC5050000.0 [1]
2-Hexadecyl-5-oxo-cyclopent-1-enecarboxylic acid methyl esterIC50129000.0 [1]
Trimethyl (1aR,1bR,2R,5S,5aS,6aS)-1a,3-dihexadecyl-6-oxo-1b,2,5,5a-tetrahydro-1H-cyclopropa[a]indene-2,5,6a-tricarboxylateIC5012500.0 [1]
(R)-4-Hexadecyl-4-hydroxy-cyclopent-2-enoneIC50200000.0 [1]
(1R,2S)-2-Hexadecyl-5-oxo-cyclopent-3-enecarboxylic acid methyl esterIC5084000.0 [1]
(3As,4R,7R,7aR)-1,6-dihexadecyl-7-methoxycarbonyl-3a,4,7,7a-tetrahydro-3H-indene-2,4-dicarboxylic acidIC502500.0 [1]
(3As,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbonyl)-3-oxo-3a,4,7,7a-tetrahydroindene-4-carboxylic acidIC508600.0 [1]
(3As,4S,7R,7aR)-1,6-dihexadecyl-3-oxo-2,7-bis(propan-2-yloxycarbonyl)-3a,4,7,7a-tetrahydroindene-4-carboxylic acidIC5020000.0 [1]
Methyl (2S,3S,4R,5E)-2-ethyl-4-hydroxy-5-(2-oxononadecylidene)-1-(2-phenylethyl)pyrrolidine-3-carboxylateIC5025000.0 [1]
Methyl (2R,3S,4R,5E)-4-hydroxy-5-(2-oxononadecylidene)-2-phenyl-1-(2-phenylethyl)pyrrolidine-3-carboxylateIC5050000.0 [1]
7-O-Ethyl 2-O,4-O-dimethyl (3aR,4R,7S,7aS)-3,5-dihexadecyl-1-oxo-3a,4,7,7a-tetrahydroindene-2,4,7-tricarboxylateIC5039700.0 [1]
7-O-Ethyl 2-O,4-O-dimethyl (3aR,4S,7S,7aS)-3,5-dihexadecyl-1-oxo-3a,4,7,7a-tetrahydroindene-2,4,7-tricarboxylateIC5048400.0 [1]
Methyl (2S,3S,4R,5E)-2-ethyl-4-hydroxy-5-(2-oxotetradecylidene)-1-(2-phenylethyl)pyrrolidine-3-carboxylateIC5050000.0 [1]
Methyl (2S,3S,4R,5E)-1-benzyl-2-ethyl-4-hydroxy-5-(2-oxotetradecylidene)pyrrolidine-3-carboxylateIC5050000.0 [1]
Methyl (2S,3S,4S,5E)-1-benzyl-2-ethyl-4-hydroxy-5-(2-oxotetradecylidene)pyrrolidine-3-carboxylateIC5050000.0 [1]
Dimethyl (3aR,4R,7S,7aS)-3,5-dihexadecyl-1-oxo-7-(2-phenylethylcarbamoyl)-3a,4,7,7a-tetrahydroindene-2,4-dicarboxylateIC5012500.0 [1]
Methyl (2R,3S,4R,5E)-4-hydroxy-1-[2-(1H-indol-3-yl)ethyl]-5-(2-oxotetradecylidene)-2-phenylpyrrolidine-3-carboxylateIC5050000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Terminal deoxynucleotidyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/terminal-deoxynucleotidyltransferase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 22). Quest Database™ Terminal deoxynucleotidyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/terminal-deoxynucleotidyltransferase-inhibitors-ic50-ki.
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