Telomerase reverse transcriptase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Homidium bromide	IC50	2500.0 [1]
	(E)-2-(3-(Naphthalen-2-yl)but-2-enamido)benzoic acid	IC50	280.0 [1]
	Telomestatin	IC50	20.0 [1]
	7,8,3',4'-Tetrahydroxyflavone	IC50	230.0 [1]
	Braco-19	IC50	90.0 [1]
	Telomerase Inhibitor IX	IC50	670.0 [1], 12100.0 [2], 12800.0 [3]
	beta-Rubromycin	IC50	1320.0 [1], 1530.0 [2], 3000.0 [3], 3060.0 [4]
	CID 11430774	IC50	45.0 [1], 52.0 [2], 63.0 [3], 5600.0 [4], 8400.0 [5]
	Phen-DC3	IC50	1.5 [1], 2.2 [2], 63.0 [3], 790.0 [4], 1500.0 [5]
	Staurosporine	IC50	4140.0 [1], 8300.0 [2], 8320.0 [3], 8970.0 [4]
	(-)-Epigallocatechin gallate	IC50	1000.0 [1], 1080.0 [2], 1180.0 [3]
	Acridine orange	IC50	12200.0 [1]
	Ethacridine	IC50	8200.0 [1]
	Acridine Yellow	IC50	21700.0 [1]
	(3R,4S,7R,10R)-3-[(1S,2S,4Ar,8aS)-2-methyl-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl]-10-hydroxy-5-oxa-1-azatricyclo[5.2.1.04,10]decane-2,6-dione	IC50	1300.0 [1]
	Meso-tetrakis(N-methyl-4-pyridyl)porphine(4+)	IC50	550.0 [1], 710.0 [2], 740.0 [3]
	N-[9,10-Dioxo-6-(3-pyrrolidin-1-ylpropanoylamino)anthracen-2-yl]-3-pyrrolidin-1-ylpropanamide	IC50	1800.0 [1]
	3-Pyrrolidin-1-YL-N-[6-(3-pyrrolidin-1-YL-propionylamino)-acridin-3-YL]-propionamide	IC50	5200.0 [1]
	3,6-Bis[3-(Azepan-1-Yl)propionamido]acridine	IC50	3100.0 [1]
	3,6-Bis[3-(heptamethyleneimino)piperizinopropionamido)acridine	IC50	50000.0 [1]
	3,6-Bis(3-piperidinopropionamido)acridine	IC50	2800.0 [1]
	2,7-Bis[3-(piperidino)propionamido]anthraquinone	IC50	3100.0 [1], 8400.0 [2]
	2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinonitrile	IC50	7000.0 [1], 77000.0 [2], 113280.0 [3]
	Tanshinone IIA	IC50	500.0 [1], 5000.0 [2]
	Tmpyp	IC50	60.0 [1], 147.0 [2]
	Isometamidium	IC50	100.0 [1], 19054607.18 [2]
	9,10-Phenanthrenequinone	IC50	500.0 [1], 5000.0 [2]
	7,8-Dihydroxyflavone	IC50	36000.0 [1]
	Helenalin	IC50	4000.0 [1]
	Cryptolepine	IC50	9400.0 [1]
	7,3',4'-Trihydroxyflavone	IC50	40000.0 [1]
	Syuiq-5	IC50	440.0 [1], 630.0 [2]
	7,8,4'-Trihydroxyflavone	IC50	3000.0 [1]
	2,6-Bis[3-(1-piperidinyl)propanoylamino]anthraquinone	IC50	4500.0 [1]
	2,7-Bis[3-(Diethylamino)Propionamido]Anthraquinone	IC50	4300.0 [1]
	Chrolactomycin	IC50	500.0 [1]
	2,7-Bis[3-(Dimethylamino)Propionamido]Anthraquinone	IC50	4700.0 [1]
	2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone	IC50	2000.0 [1], 6700.0 [2]
	N-[9-(4-Aminoanilino)-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamide	IC50	60.0 [1], 74.0 [2]
	N-[9-[2-(1-Methylpyrrolidin-2-yl)ethylamino]-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamide	IC50	18.0 [1]
	N',N'-Dimethyl-N-(16-nitro-4,12-diazapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-1(13),2(11),3,5,7,9,14(19),15,17,20-decaen-3-yl)propane-1,3-diamine	IC50	500.0 [1]
	3-Morpholin-4-yl-N-[7-(3-morpholin-4-ylpropanoylamino)-9,10-dioxoanthracen-2-yl]propanamide	IC50	50000.0 [1]
	3,6-Bis[(3-morpholinopropionamido)] acridine	IC50	50000.0 [1]
	3,6-Bis[3-(4-methylpiperidino)propionamido]acridine	IC50	1350.0 [1]
	3-(1,3,3-Trimethyl-6-azabicyclo[3.2.1]octan-6-yl)-N-[6-[3-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)propanoylamino]acridin-3-yl]propanamide	IC50	50000.0 [1]
	3-(4-Benzylpiperidin-1-yl)-N-[6-[3-(4-benzylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamide	IC50	50000.0 [1]
	3-(2-Ethylpiperidin-1-yl)-N-[6-[3-(2-ethylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamide	IC50	2700.0 [1]
	3-Diethylamino-N-[6-(3-diethylamino-propionylamino)-acridin-3-yl]-propionamide	IC50	5800.0 [1]
	3-Dimethylamino-N-[6-(3-dimethylamino-propionylamino)-acridin-3-yl]-propionamide	IC50	8200.0 [1]
	3-(3-Methylpiperidin-1-yl)-N-[6-[3-(3-methylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamide	IC50	4400.0 [1]
	3-(2-Methylpiperidin-1-yl)-N-[6-[3-(2-methylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamide	IC50	2600.0 [1]
	3-[2-(Hydroxymethyl)piperidin-1-yl]-N-[6-[3-[2-(hydroxymethyl)piperidin-1-yl]propanoylamino]acridin-3-yl]propanamide	IC50	5400.0 [1]
	3-(4-Hydroxypiperidin-1-yl)-N-[6-[3-(4-hydroxypiperidin-1-yl)propanoylamino]acridin-3-yl]propanamide	IC50	8000.0 [1]
	3-[2-(2-Hydroxyethyl)piperidin-1-yl]-N-[6-[3-[2-(2-hydroxyethyl)piperidin-1-yl]propanoylamino]acridin-3-yl]propanamide	IC50	4100.0 [1]
	5-Morpholin-4-yl-2-[[(E)-3-naphthalen-2-ylbut-2-enoyl]amino]benzoic acid	IC50	470.0 [1]
	4,11-Diaminonaphtho[2,3-f][1]benzothiole-5,10-dione	IC50	10000.0 [1], 33000.0 [2]
	9,12,15,29,32,35,42,44-Octazaheptacyclo[35.3.1.13,7.14,40.117,21.120,24.123,27]hexatetraconta-1(40),2,4(42),5,7(46),17(45),18,20(44),21,23,25,27(43),37(41),38-tetradecaene	IC50	750.0 [1]
	3-(4-Methylmorpholin-4-ium-4-yl)-N-[7-[3-(4-methylmorpholin-4-ium-4-yl)propanoylamino]-9,10-dioxoanthracen-2-yl]propanamide	IC50	16500.0 [1]
	[3-[[9,10-Dioxo-7-[3-(trimethylazaniumyl)propanoylamino]anthracen-2-yl]amino]-3-oxopropyl]-trimethylazanium	IC50	14500.0 [1]
	3-(1-Methylpiperidin-1-ium-1-yl)-N-[7-[3-(1-methylpiperidin-1-ium-1-yl)propanoylamino]-9,10-dioxoanthracen-2-yl]propanamide	IC50	7800.0 [1]
	2-(3,4-Dimethoxyphenyl)-7,8-dihydroxy-4H-chromen-4-one	IC50	11700.0 [1]
	2-(3,4-Dihydroxyphenyl)-8-hydroxy-4H-chromen-4-one	IC50	40000.0 [1]
	4,11-Bis[2-(methylamino)ethylamino]naphtho[2,3-f][1]benzothiole-5,10-dione;hydrochloride	IC50	500.0 [1], 700.0 [2]
	2-[2-[[4-[2-(Diaminomethylideneamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl]amino]ethyl]guanidine;hydrochloride	IC50	80.0 [1], 700.0 [2]
	(3-Chlorophenyl) 12-[[2-[1-[3-(3-methylindol-1-yl)propyl]indol-3-yl]acetyl]amino]dodecyl hydrogen phosphate;N,N-diethylethanamine	IC50	3400.0 [1], 79000.0 [2]
	6-Formylpyridine-2-carbothionic acid-S-3,4-dichlorophenyl ester	IC50	24000.0 [1], 33090.0 [2]
	1,4-Bis[[3-(4-methylmorpholinium-4-yl)propionyl]amino]-9,10-anthraquinone	IC50	34500.0 [1]
	[3-[[9,10-Dioxo-6-[3-(trimethylazaniumyl)propanoylamino]anthracen-2-yl]amino]-3-oxopropyl]-trimethylazanium	IC50	17300.0 [1]
	[3-[[7-[3-[Diethyl(methyl)azaniumyl]propanoylamino]-9,10-dioxoanthracen-2-yl]amino]-3-oxopropyl]-diethyl-methylazanium	IC50	20000.0 [1]
	2-[2-[(11-Amino-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl)amino]ethyl]guanidine	IC50	900.0 [1], 2000.0 [2]
	2-[2-[(4-Amino-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl)amino]ethyl]guanidine	IC50	500.0 [1], 3000.0 [2]
	2-[2-[[11-[2-(Methylamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidine	IC50	300.0 [1], 600.0 [2]
	2-[2-[[4-[2-(Methylamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl]amino]ethyl]guanidine	IC50	50.0 [1], 1100.0 [2]
	2-[2-[[11-(2-Aminoethylamino)-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidine	IC50	100.0 [1], 800.0 [2]
	2-[2-[[11-(3-Aminopropylamino)-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidine	IC50	70.0 [1], 700.0 [2]
	N'-[2-[[11-[2-(1-Aminoethylideneamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]ethanimidamide	IC50	300.0 [1], 470.0 [2]
	1,4-Bis[[3-(1-methylpiperidinium-1-yl)propionyl]amino]-9,10-anthraquinone	IC50	11100.0 [1]
	12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl cyclohexyl hydrogen phosphate	IC50	8700.0 [1], 101000.0 [2]
	12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl (3-chlorophenyl) hydrogen phosphate	IC50	2500.0 [1], 70000.0 [2]
	12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl phenyl hydrogen phosphate	IC50	6700.0 [1], 61000.0 [2]
	Doxorubicin	IC50	73000.0 [1]
	Camptothecin	IC50	300000.0 [1]
	Resveratrol	IC50	85000.0 [1]
	Oleic acid	IC50	8600.0 [1]
	Berberine	IC50	37000.0 [1]
	1-(6-((3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione	IC50	200.0 [1]
	Celastrol	IC50	780.0 [1]
	Allicin	IC50	500.0 [1]
	Costunolide	IC50	65000.0 [1]
	2'-3'-Dideoxyguanosine-5'-triphosphate	IC50	8600.0 [1]
	Vaccenic acid	IC50	16000.0 [1]
	Unii-ST04094S3X	IC50	37300.0 [1]
	3',4'-Dihydroxyflavone	IC50	40000.0 [1]
	Petroselinic acid	IC50	15000.0 [1]
	3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-KL]acridin-13-ium	IC50	331131121.48 [1]
	Altertoxin I	IC50	1000000.0 [1]
	7,8,3'-Trihydroxyflavone	IC50	50000.0 [1]
	Meridine	IC50	11000.0 [1]
	Okanin	IC50	6000.0 [1]
	Telomerase Inhibitor IV	IC50	200.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Telomerase reverse transcriptase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 30 Mar. 2025, https://www.aatbio.com/data-sets/telomerase-reverse-transcriptase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, March 30). Quest Database™ Telomerase reverse transcriptase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/telomerase-reverse-transcriptase-inhibitors-ic50-ki.
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