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Sucrase-isomaltase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
BaicaleinIC5035000.0 [1], 52000.0 [2]
AMP-DeoxynojirimycinIC50500.0 [1], 600.0 [2]
(2S,3R,4R,5S)-1-[5-(1-Adamantylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1], 1000000.0 [2]
(2S,3R,4S,5S)-6-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]hexane-1,2,3,4,5-pentolKi103.0 [1], 302.0 [2]
(2S,3R,4S,5S)-6-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-4-methoxyhexane-1,2,3,5-tetrolKi7.0 [1], 35.0 [2]
1-DeoxynojirimycinIC502000.0 [1]
MiglustatIC50500.0 [1]
MiglitolIC50500.0 [1]
MigalastatIC50260.0 [1]
LucerastatIC50460.0 [1]
ValienamineIC5053000.0 [1]
ValiolamineIC5049.0 [1]
ValidamineIC507500.0 [1]
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3R,4R,5S)-IC501000000.0 [1]
(2S,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triolIC501000000.0 [1]
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5S)-IC50220000.0 [1]
(2S,5S,8S,14S,20S,23S)-2,20-Dibenzyl-5-[(2R)-butan-2-yl]-8-(2-methylpropyl)-1,4,7,10,16,19,22-heptazatricyclo[21.2.1.010,14]hexacosane-3,6,9,15,18,21,25,26-octoneIC50305000.0 [1]
(2R,3S,4R,5S)-1-[5-(1-Adamantylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC503500.0 [1]
5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC505.2 [1]
(2R,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50400.0 [1]
(2S,3R,4R,5S)-1-[5-[(3-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
5-(2-Hydroxy-1-hydroxymethyl-ethylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50180.0 [1]
(2S,3S,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triolIC50450000.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC501250.0 [1]
(2S,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC5070000.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC501500.0 [1]
(2R,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50250.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50250.0 [1]
(2R,3R,4R,5S)-1-[5-[(3-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50400.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(2-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50200.0 [1]
(2R,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC5035000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(2-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC5095000.0 [1]
(1S,2S,3R,4S,5S)-5-[Bis(hydroxymethyl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC504.6 [1]
5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC509.3 [1]
5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC5015.0 [1]
5-(4-Bromo-benzylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC5015.0 [1]
6-(2-Hydroxy-1-hydroxymethyl-ethylamino)-4-hydroxymethyl-cyclohex-4-ene-1,2,3-triolIC50180.0 [1]
1-Hydroxymethyl-5-phenethylamino-cyclohexane-1,2,3,4-tetraolIC502.3 [1]
5-(3,7-Dimethyl-octa-2,6-dienylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC5011.0 [1]
(1S,2S,3R,4S,5S)-5-[[(1S,2S)-2-Hydroxycyclohexyl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC50160.0 [1]
1-Hydroxymethyl-5-[(thiophen-2-ylmethyl)-amino]-cyclohexane-1,2,3,4-tetraolIC503.3 [1]
5-(3,5-Di-tert-butyl-4-hydroxy-benzylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC506.8 [1]
1-Hydroxymethyl-5-(3-phenyl-allylamino)-cyclohexane-1,2,3,4-tetraolIC5014.0 [1]
1-Hydroxymethyl-5-[(pyridin-3-ylmethyl)-amino]-cyclohexane-1,2,3,4-tetraolIC5015.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50200.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50250.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1R)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50500.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1R)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3S,4R,5S)-1-[5-(1-Adamantylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC501000000.0 [1]
(1S,2S,3R,6S)-6-[[(2R,3S,4S,5R,6S)-4,5-Dihydroxy-6-methoxy-2-methyloxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triolIC5016000.0 [1]
(1S,2S,3R,6S)-6-[[(2S,3S,4S,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triolIC50320.0 [1]
(1S,2S,3R,4S,5S)-5-[[(2R,3R,4S,5R,6S)-4,5-Dihydroxy-6-methoxy-2-methyloxan-3-yl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC50250.0 [1]
(1S,2S,3R,4S,5S)-1-(Hydroxymethyl)-5-[[(1S,2S,3S,4S,6S)-2,3,4-trihydroxy-6-methylcyclohexyl]amino]cyclohexane-1,2,3,4-tetrolIC5036.0 [1]
(1S,2S,3R,4S,5S)-5-[[(1S,2S,3S,4S,6S)-4-Amino-2,3-dihydroxy-6-methylcyclohexyl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC505300.0 [1]
(1S,2S,3R,6S)-6-[[(2R,3R,4S,5R,6S)-4,5-Dihydroxy-6-methoxy-2-methyloxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triolIC5066000.0 [1]
(1S,2S,3R,4S,5S)-5-[[(2R,3S,4S,5R,6S)-4,5-Dihydroxy-6-methoxy-2-methyloxan-3-yl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC5010.0 [1]
(1S,2S,3R,4S,5S)-5-[[(2S,3R,4S,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC50230.0 [1]
(1S,2S,3R,6S)-6-[[(2S,3R,4S,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triolIC504000.0 [1]
(1S,2S,3R,4S,5S)-5-[[(1R,2S,3S,4S,6S)-4-Amino-2,3-dihydroxy-6-methylcyclohexyl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC507.5 [1]
(1S,2S,3R,4S,5S)-1-(Hydroxymethyl)-5-[[(1S,2S,3S,4R,6S)-2,3,4-trihydroxy-6-methylcyclohexyl]amino]cyclohexane-1,2,3,4-tetrolIC5035.0 [1]
(1S,2S,3R,4S,5S)-5-[[(2S,3S,4S,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC5080.0 [1]
(1S,2S,3R,4S,5S)-1-(Hydroxymethyl)-5-[[(1S)-2-hydroxy-1-phenylethyl]amino]cyclohexane-1,2,3,4-tetrolIC50300.0 [1]
(1S,2R,3S,4S,5S)-1-(Hydroxymethyl)-5-[[(2R)-2-hydroxy-2-phenylethyl]amino]cyclohexane-1,2,3,4-tetrolIC502.9 [1]
(1S,2S,3R,4S,5S)-1-(Hydroxymethyl)-5-[[(1R)-2-hydroxy-1-phenylethyl]amino]cyclohexane-1,2,3,4-tetrolIC506.6 [1]
(1S,2R,3S,4S,5S)-1-(Hydroxymethyl)-5-[[(2S)-2-hydroxy-2-phenylethyl]amino]cyclohexane-1,2,3,4-tetrolIC50190.0 [1]
Items per page: 1 - 10 of 72
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References

This online tool may be cited as follows

MLA

"Quest Database™ Sucrase-isomaltase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/sucrase-isomaltase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Sucrase-isomaltase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sucrase-isomaltase-inhibitors-ic50-ki.
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