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Succinate receptor 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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CID 53358901IC5035.0 [1]
2-[4-(3-Chlorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-oxadiazoleIC5040.0 [1]
Hgpr91 antagonist 1IC507.0 [1]
N-[[4-(3-Methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5030.0 [1]
Methyl 2-fluoro-6-[3-fluoro-4-[[4-(1,8-naphthyridin-2-yl)butanoylamino]methyl]phenyl]benzoateIC50800.0 [1]
N-[[4-(3-Methoxyphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC501000.0 [1]
2,2-Difluoro-N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamideIC5019.0 [1]
N-[[3-(3-Chlorophenyl)-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5065.0 [1]
N-[[5-[4-Fluoro-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC501000.0 [1]
2-[4-(3-Chlorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-thiadiazoleIC503000.0 [1]
2-[3-Chloro-4-(trifluoromethoxy)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC50180.0 [1]
2-[4-Fluoro-3-(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC502000.0 [1]
N-[[4-[4-Fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5022.0 [1]
N-[[2-Fluoro-4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5041.0 [1]
N-[[5-[4-Fluoro-3-(trifluoromethyl)phenyl]pyrimidin-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50200.0 [1]
2-[4-(1,8-Naphthyridin-2-yl)butyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazoleIC503000.0 [1]
2-(4-Chlorophenyl)-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC503000.0 [1]
2-[4-Chloro-3-(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC50160.0 [1]
4-(1,8-Naphthyridin-2-yl)-N-[1-[4-[3-(trifluoromethyl)phenyl]phenyl]ethyl]butanamideIC5016.0 [1]
N-[(1S)-1-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-methyl-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamideIC5014.0 [1]
N-[[6-[4-Fluoro-3-(trifluoromethyl)phenyl]pyridazin-3-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50720.0 [1]
N-[[3-(3-Chloro-4-fluorophenyl)-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5090.0 [1]
N-[[4-(3-Chlorophenyl)-1,3-thiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50300.0 [1]
N-[[4-(3-Ethylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5065.0 [1]
4-(1,8-Naphthyridin-2-yl)-N-[[4-[3-(trifluoromethoxy)phenyl]phenyl]methyl]butanamideIC50500.0 [1]
N-[[2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50700.0 [1]
2-[4-(3-Chloro-4-fluorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-oxadiazoleIC50100.0 [1]
2-[4-(1,8-Naphthyridin-2-yl)butyl]-5-[4-(trifluoromethoxy)phenyl]-1,3,4-oxadiazoleIC503000.0 [1]
N-[[4-(4-Chloro-3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50300.0 [1]
N-[[4-(3-Chloro-4-fluorophenyl)phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamideIC5031.0 [1]
3,3,3-Trifluoro-N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamideIC5034.0 [1]
2-Amino-N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamideIC50330.0 [1]
2-[3,4-Bis(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC50170.0 [1]
2-[4-Fluoro-3-(trifluoromethoxy)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazoleIC504000.0 [1]
N-[[4-[4-Fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-methyl-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamideIC5017.0 [1]
N-[[5-[4-Fluoro-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50270.0 [1]
2-[3-(1,8-Naphthyridin-2-yl)propyl]-5-[4-[3-(trifluoromethyl)phenyl]phenyl]-1,3,4-oxadiazoleIC50200.0 [1]
2-[3-[3-[4-(3-Chloro-4-fluorophenyl)phenyl]-1H-1,2,4-triazol-5-yl]propyl]-1,8-naphthyridineIC501000.0 [1]
4-(1,8-Naphthyridin-2-yl)-N-[(4-phenylphenyl)methyl]butanamideIC501000.0 [1]
N-[(1S)-1-[4-(3-Chlorophenyl)phenyl]ethyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5011.0 [1]
3,3,3-Trifluoro-N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamideIC5016.0 [1]
N-[[4-(3-Chlorophenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5040.0 [1]
N-[[4-(3-Chloro-4-fluorophenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5038.0 [1]
N-[[4-[4-Fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamideIC5075.0 [1]
N-[(1S)-1-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamideIC5018.0 [1]
N-[[2-[4-Fluoro-3-(trifluoromethyl)phenyl]pyrimidin-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC5049.0 [1]
N-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]pyrazol-4-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamideIC50210.0 [1]
Items per page: 1 - 10 of 47
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References

This online tool may be cited as follows

MLA

"Quest Database™ Succinate receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/succinate-receptor-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Succinate receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/succinate-receptor-1-inhibitors-ic50-ki.
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