Stem cell growth factor receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Imatinib	IC50	100.0 [1]
	Sunitinib	IC50	10.0 [1]
	Sunitinib	Ki	4.0 [1]
	Dasatinib	IC50	5.0 [1]
	Staurosporine	IC50	4.5 [1]
	Nilotinib	IC50	200.0 [1]
	Cabozantinib	IC50	4.6 [1]
	Foretinib	IC50	6.7 [1]
	4-Methyl-N-[3-methyl-5-(4-methylimidazol-1-yl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide	IC50	200.0 [1]
	4-Methyl-N-[3-(4-methylimidazol-1-yl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide	IC50	200.0 [1]
	N-[3-Fluoro-5-(4-methylimidazol-1-yl)phenyl]-4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide	IC50	200.0 [1]
	Bosutinib	IC50	32.0 [1], 132.0 [2], 181.0 [3], 2772.0 [4], 6313.0 [5]
	Sorafenib	IC50	10.0 [1], 31.0 [2], 68.0 [3]
	Ellipticine	IC50	200.0 [1], 10000.0 [2]
	Dovitinib	IC50	1.0 [1], 1.1 [2], 3.0 [3], 48.3 [4]
	Elliptinium	IC50	10.0 [1], 400.0 [2]
	9-Hydroxyellipticine	IC50	10.0 [1], 400.0 [2]
	9-Methoxyellipticine	IC50	300.0 [1], 500.0 [2], 600.0 [3], 800.0 [4]
	1-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylphenyl)urea	IC50	6.0 [1], 6.03 [2]
	Datelliptium	IC50	10.0 [1], 300.0 [2], 450.0 [3]
	Thienopyrimidine deriv. 11	IC50	8.91 [1], 9.0 [2]
	1,3-Propanediamine, N,N-diethyl-N'-(9-methoxy-5-methyl-6H-pyrido(4,3-b)carbazol-1-yl)-	IC50	400.0 [1], 600.0 [2], 2000.0 [3], 2500.0 [4]
	6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-	IC50	10.0 [1], 1200.0 [2], 1400.0 [3]
	9-Bromoellipticine	IC50	200.0 [1], 300.0 [2], 10000.0 [3]
	N',N'-Diethyl-N-(2-methyl-6,15,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1,3(8),4,6,9,11(16),12,14-octaen-7-yl)propane-1,3-diamine	IC50	250.0 [1], 300.0 [2], 1900.0 [3], 2300.0 [4]
	4-(4-(5-Benzylpyrimidin-2-yl)piperazin-1-yl)quinazoline	IC50	316.0 [1], 699.0 [2], 2823.0 [3], 10000.0 [4]
	Pazopanib	IC50	74.0 [1], 118.0 [2]
	Vatalanib	IC50	620.0 [1], 700.0 [2], 730.0 [3]
	Semaxanib	IC50	35.0 [1], 400.0 [2], 660.0 [3]
	Ponatinib	IC50	1.7 [1], 4.9 [2]
	Saracatinib	IC50	200.0 [1]
	Linifanib	IC50	14.0 [1], 16.0 [2]
	Osi-930	IC50	10.0 [1], 29.0 [2], 80.0 [3]
	3-N-[4-(4-Morpholin-4-ylcyclohexyl)phenyl]-1-pyridin-2-yl-1,2,4-triazole-3,5-diamine	IC50	4.0 [1]
	3-N-[4-(4-Morpholin-4-ylcyclohexyl)phenyl]-1-pyridin-2-yl-1,2,4-triazole-3,5-diamine	Ki	1.0 [1]
	Thienopyrimidine deriv. 20	IC50	21.88 [1], 22.0 [2]
	Thienopyrimidine deriv. 24	IC50	140.0 [1], 141.25 [2]
	Thienopyrimidine deriv. 26	IC50	19.0 [1], 19.05 [2]
	Thienopyrimidine deriv. 88	IC50	26.92 [1], 27.0 [2]
	Thienopyrimidine deriv. 91	IC50	38.0 [1], 38.02 [2]
	Thienopyrimidine deriv. 93	IC50	28.0 [1], 28.18 [2]
	Thienopyrimidine deriv. 10	IC50	67.61 [1], 68.0 [2]
	Thienopyrimidine deriv. 13	IC50	50.0 [1], 50.12 [2]
	Thienopyrimidine deriv. 14	IC50	19.0 [1], 19.05 [2]
	Thienopyrimidine deriv. 15	IC50	15.0 [1], 15.14 [2]
	Thienopyrimidine deriv. 18	IC50	33.0 [1], 33.11 [2]
	Thienopyrimidine deriv. 19	IC50	109.65 [1], 110.0 [2]
	Thienopyrimidine deriv. 21	IC50	28.84 [1], 29.0 [2]
	Thienopyrimidine deriv. 23	IC50	47.86 [1], 48.0 [2]
	Thienopyrimidine deriv. 27	IC50	173.78 [1], 175.0 [2]
	Thienopyrimidine deriv. 28	IC50	181.97 [1], 182.0 [2]
	Thienopyrimidine deriv. 51	IC50	158.49 [1], 160.0 [2]
	Thienopyrimidine deriv. 52	IC50	398.11 [1], 400.0 [2]
	Thienopyrimidine deriv. 53	IC50	930.0 [1], 933.25 [2]
	Thienopyrimidine deriv. 59	IC50	575.44 [1], 580.0 [2]
	Thienopyrimidine deriv. 60	IC50	794.33 [1], 800.0 [2]
	Thienopyrimidine deriv. 79	IC50	81.28 [1], 82.0 [2]
	Thienopyrimidine deriv. 83	IC50	954.99 [1], 960.0 [2]
	Thienopyrimidine deriv. 85	IC50	360.0 [1], 363.08 [2]
	Thienopyrimidine deriv. 87	IC50	810.0 [1], 812.83 [2]
	Thienopyrimidine deriv. 90	IC50	180.0 [1], 181.97 [2]
	Thienopyrimidine deriv. 92	IC50	53.7 [1], 54.0 [2]
	Taxifolin	IC50	15700.0 [1], 21900.0 [2]
	Ceritinib	IC50	1280.0 [1], 2855.0 [2]
	Tandutinib	IC50	170.0 [1], 220.0 [2]
	Pectolinarigenin	IC50	600.0 [1], 1500.0 [2]
	Bms-777607	IC50	144.0 [1], 500.0 [2]
	JNJ-28312141 free base	IC50	5.0 [1], 41.0 [2]
	4-[2-(Butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol	IC50	8.18 [1]
	Tafetinib	IC50	2.4 [1], 5.0 [2]
	2-[2-[4-[4-(4-Tert-butylanilino)phenoxy]-6-methoxyquinolin-7-yl]oxyethylamino]ethanol	IC50	69.0 [1], 100.0 [2]
	3-(2-Aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one	IC50	16.0 [1], 22.0 [2]
	7,8-Dihydroxy-5,6-dimethoxy-2-phenylchromen-4-one	IC50	500.0 [1], 7800.0 [2]
	Flt-3 Inhibitor II	IC50	500.0 [1]
	(2Z)-6-Hydroxy-2-(4-methoxybenzylidene)-1-benzofuran-3(2H)-one	IC50	1400.0 [1], 15600.0 [2]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	IC50	41.0 [1]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	17.0 [1]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(4-fluoro-3-methylphenyl)urea	IC50	10.0 [1]
	2-Methyl-N-pyrimidin-5-yl-5-[[3-(trifluoromethyl)benzoyl]amino]benzamide	IC50	14.0 [1]
	N-[4-[4-[[5-Tert-butyl-2-(3-methylphenyl)pyrazol-3-yl]carbamoylamino]anilino]quinazolin-6-yl]propanamide	IC50	21.9 [1], 155.0 [2]
	9-Ethyl-6,6-dimethyl-8-[4-(oxetan-3-yl)piperazin-1-yl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile	IC50	5000.0 [1]
	Thienopyrimidine deriv. 74	IC50	28.0 [1], 28.18 [2]
	Thienopyrimidine deriv. 12	IC50	83.0 [1], 83.18 [2]
	Thienopyrimidine deriv. 17	IC50	26.92 [1], 27.0 [2]
	Thienopyrimidine deriv. 84	IC50	37.0 [1], 37.15 [2]
	Thienopyrimidine deriv. 86	IC50	25.7 [1], 26.0 [2]
	(1S)-2-(1H-Indol-3-YL)-1-[({5-[(E)-2-pyridin-4-ylvinyl]pyridin-3-YL}oxy)methyl]ethylamine	IC50	50000.0 [1]
	N-(1,3-Benzodioxol-5-ylmethyl)-4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carbothioamide	IC50	220.0 [1], 1800.0 [2]
	Methanesulfonic acid;N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide	IC50	293.0 [1], 342.0 [2]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(3-bromophenyl)urea	IC50	69.0 [1]
	1-(4-(3-Amino-7-((4-methylpiperazin-1-yl)methyl)-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	290.0 [1]
	1-(4-(3-Amino-7-fluoro-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	5.0 [1]
	1-(4-(3-Amino-7-bromo-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	39.0 [1]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(3-ethylphenyl)urea	IC50	42.0 [1]
	1-(4-(3-Amino-7-(2-morpholinoethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	50.0 [1]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(3-chlorophenyl)urea	IC50	13.0 [1]
	1-(4-(3-Amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea	IC50	53.0 [1]
	4-(6,7-Dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]piperazine-1-carbothioamide	IC50	28000.0 [1]
	1-[4-(3-Amino-1H-indazol-4-yl)phenyl]-3-thiophen-3-ylurea	IC50	42.0 [1]
	1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-cyclopentylurea	IC50	850.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Stem cell growth factor receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/stem-cell-growth-factor-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 21). Quest Database™ Stem cell growth factor receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/stem-cell-growth-factor-receptor-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan