![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_34bf2a73501934831284d54c5503e8e2.svg) | Zaragozic acid A | IC50 | 5.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_627c88310e3d53378e521c331e6b5311.svg) | N-Geranyl-N'-(2-adamantyl)ethane-1,2-diamine | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_627c88310e3d53378e521c331e6b5311.svg) | N-Geranyl-N'-(2-adamantyl)ethane-1,2-diamine | Ki | 740.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_3bd24f335be286a839c03fc507695c78.svg) | Lapaquistat | IC50 | 45.0 [1], 260.0 [2] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_d2526075f4375d819861ce4348f44d66.svg) | Lapaquistat acetate | IC50 | 78.0 [1], 213.0 [2] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_fbf4bade7c87959ef03cc3b8dd9c177b.svg) | Ethyl 4-(1-azabicyclo[2.2.2]oct-2-en-3-yl)benzoate | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b700c3986378279a2608428a21bbe8e9.svg) | (2S)-2-[2-[[(2S,3S)-4-(3,4-Dichlorophenyl)-3-(3-fluoro-4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid | IC50 | 0.52 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_81af8877c0a8c32165f86d729092ee41.svg) | Amiodarone | IC50 | 8000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_77c391ecc2a860f34ce44899df893a6e.svg) | Zaragozic acid C | IC50 | 0.3 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c56d06c792e0c29c058b2b91062ed7b2.svg) | FTase Inhibitor I | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_aa4c95106da00c24ad4fef134f501c68.svg) | [(5-Chloro-pyridin-2-ylamino)-phosphono-methyl]-phosphonic acid | IC50 | 240.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_18dd4db44b8f9349d5d2085b1d89e135.svg) | (3r)-3-{[2-Benzyl-6-(3-Methoxypropoxy)pyridin-3-Yl]ethynyl}-1-Azabicyclo[2.2.2]octan-3-Ol | IC50 | 6.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_721f4d6b61149731327aa04f3a683ccd.svg) | (3R)-3-[2-[2-Benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl]ethynyl]-1-azabicyclo[2.2.2]octan-3-ol | IC50 | 1.5 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_7d0048fff44d678dff4a2b7631ecb465.svg) | Tripotassium;4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 23.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_1c0c5daa11fdd8a70e80edbc69d21226.svg) | [[(6-Methylpyridin-2-yl)amino]-phosphonomethyl]phosphonic acid | IC50 | 1290.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_59ee1cb6a104b50994ce62620b6d0eba.svg) | Tripotassium (1S)-4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 1900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_cc7b74f9d0988f5ad0922dab1aff9bb5.svg) | N-6-Chloro-(3-pyridyl)-aminomethylene-1,1-bisphosphonate | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c406dc51a54846b6bac9dfc34d76ea24.svg) | {[(4,6-Dimethylpyridin-2-yl)amino]methanediyl}bis(phosphonic acid) | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_922a60556ff527b3297a55d6f98607ed.svg) | (2E, 6E)-Farnesylbisphosphonate | IC50 | 18.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_8032a3eb2b77f313cbd2e98455b1c67d.svg) | 3-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]propanoic acid | IC50 | 15.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_e7b6e8de7a826e78d8eedfc464a7679e.svg) | 2-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]acetic acid | IC50 | 15.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a088725b93c6e117268e61c7be71201f.svg) | 3-(6-Methoxy-2-naphthyl)-1-azabicyclo[2.2.2]oct-2-ene | IC50 | 2800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_f8332c8ea01653c3a9c6e4fd661f8e80.svg) | Tripotassium;4-[4-(4-methylphenyl)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 290.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c7048bd467433d3bddbe958a6c9cc415.svg) | Tripotassium;4-[4-(4-butylphenyl)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 130.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b08a45f5cdfb48e0447d58a078ac34e0.svg) | 3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene | IC50 | 250.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_9ca1382855c4944aa776f04d03e1c7fb.svg) | Tripotassium;1-phosphonato-4-[3-(4-propylphenoxy)phenyl]butane-1-sulfonate | IC50 | 1900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_9ea376a2f9d06003725cae0d53262077.svg) | Tripotassium;4-[3-(2-benzylphenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 3.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_57af16b934c8fe84d89cead753c0d4ad.svg) | Tripotassium;4-(3-benzylphenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 69.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_5f0a6d1d1f41b72edbe6782d8eacebeb.svg) | CID 44185378 | Ki | 520.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_8623d696d7eba7e3aa4f47422e0f0717.svg) | CID 44185382 | Ki | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_f0c2600b8f75ef0061e68979c8ea40af.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-[(E,4S,6S)-4,6-dimethyloct-2-enoyl]oxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 0.24 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_597748e2df089b7efece9b8285497b53.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(11-phenoxyundecoxycarbonyloxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 0.28 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_829b48418fc356f75c7b39ada0c82f1d.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-dodecoxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 0.3 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_7889d9ac04076c58d5cb2aa875d26772.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-decoxycarbonyloxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 0.64 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_765365019c44e38eeaa3f28a726c47c2.svg) | Ethyl 2-[4-[2-(3-hydroxy-1-azabicyclo[2.2.2]octan-3-yl)ethynyl]phenyl]acetate | IC50 | 660.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_e00c6540206cbd2f0b3617700328a9a5.svg) | (2R)-2-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]propanoic acid | IC50 | 18.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a6c84a05b22d4a0ed4ca56c27a78b7ec.svg) | (2S)-2-[[(3S,6R,8Ar)-6-benzyl-6-[[(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-sulfanylpropanoyl]amino]-5-oxo-1,2,3,7,8,8a-hexahydroindolizine-3-carbonyl]amino]-4-methylsulfanylbutanoic acid | IC50 | 5000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_6e53037b66a1a661830faec385fc7269.svg) | 2-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]-methylamino]acetic acid | IC50 | 18.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_1d74eb655bae2fe82bf97569c84772eb.svg) | 4-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]butanoic acid | IC50 | 32.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_233d125d608e9e43284ae1e226b1d4fa.svg) | 3-[1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]propanoic acid | IC50 | 61.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_5759ab961219eae64ce792706a740243.svg) | (2S)-2-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]propanoic acid | IC50 | 21.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a63bbe5a6fdc0e0616a1e2baca6024a5.svg) | 4-[1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]butanoic acid | IC50 | 70.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_e2b1ac230442152deb45efe054f8e7fe.svg) | 2-[1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(2,2-dimethyl-3-propanoyloxypropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid | IC50 | 87.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_78a3af222c103dac884f91a2dc6fe075.svg) | 5-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]pentanoic acid | IC50 | 38.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b88dfa61e6bef67ac81c89aca126eff5.svg) | 2-[1-[2-[(3R,5S)-1-(3-Butanoyloxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid | IC50 | 93.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a255ab3ed329311b72aeaabf156a6d36.svg) | 2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetic acid | IC50 | 223.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_f633e27413c22109255c9809ede17998.svg) | 1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidine-4-carboxylic acid | IC50 | 18.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b67e506c23fd6aaf009af5af36a45ffb.svg) | 2-[1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-[2,2-dimethyl-3-(2-methylpropanoyloxy)propyl]-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid | IC50 | 89.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_8b09610d689e02fb9cad7e347253ef68.svg) | Tripotassium;4-(4-phenylphenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 350.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_6ca18a8897a4209306717d8eaf1aeaee.svg) | Tetrapotassium;dioxido-oxo-[4-(4-phenylphenyl)-1-phosphonatobutyl]-lambda5-phosphane | IC50 | 1.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_5467fa7a5db51f48e3b1d9f6ffddd025.svg) | 2-[8-Chloro-6-(2,3-dimethoxyphenyl)-1-propan-2-yl-4,6-dihydro-[2]benzoxepino[4,5-c][1,2]oxazol-4-yl]acetic acid | IC50 | 169.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a8a99dbe14c37fa1cf2d9280b7e78415.svg) | Tripotassium;4-[3-(3,4-dichlorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 14.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_5e614386c5382289c9701adfc7036445.svg) | Tripotassium;4-[3-(3,5-difluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 32.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_ca9a8d6c65bfcbc9dbac61905a03ba83.svg) | Tripotassium;4-[2-fluoro-5-(4-fluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 4.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_e34b37e6241c631b3edc0b9ccb081c73.svg) | Tripotassium;methyl-[4-(4-phenylphenyl)-1-phosphonatobutyl]phosphinate | IC50 | 72.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_fbeed1d66c529e2022dff21524ab344c.svg) | Tripotassium;1-phosphonato-4-[3-[4-(trifluoromethyl)phenoxy]phenyl]butane-1-sulfonate | IC50 | 170.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_6bb8c96af22a0f1a65250f18142d0a39.svg) | Tripotassium;(1R)-4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 1900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_415d481a197aef77d7b93e4e057687c6.svg) | Tripotassium;3-(3-phenoxyphenyl)-1-phosphonatopropane-1-sulfonate | IC50 | 550.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_6028b762c88caf55b82b9b04ba0868e4.svg) | Tripotassium;4-(3-anilinophenyl)-1-phosphonatobutane-1-sulfonate | IC50 | 79.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c3a3e1995dd68bf7b3f4ab8112b9a1ca.svg) | Tripotassium;4-[3-(2-fluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 5.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c53d60b02cae2dfc9c786d83b1e72bd7.svg) | Tripotassium;1-phosphonato-4-[3-[3-(trifluoromethyl)phenoxy]phenyl]butane-1-sulfonate | IC50 | 69.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_fb67ec5d7df6b418a4415c6651ad9431.svg) | Tripotassium;4-[3-(4-chlorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 20.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_fea87f874214f80f948202ad5d540169.svg) | Tripotassium;4-[3-(4-tert-butylphenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b6335f158c431e409a10a984d796e893.svg) | Tripotassium;4-[3-(4-benzylphenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 720.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_53d3c8e244c6353f6f9b3cb363ae9f0a.svg) | Dipotassium (2-oxo-2-{[3-(3-phenoxyphenyl)propyl]amino}ethyl)phosphonate | Ki | 530.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_f8a614f5a96261babdf45ba621d763e2.svg) | [2-Oxo-2-[3-(4-phenylphenyl)propylamino]ethyl]phosphonic acid | Ki | 30000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_ea0f42f15fd866afcd4b90b2e37f2cbf.svg) | N-[3-(3-Phenoxyphenyl)propyl]sulfoacetamide | Ki | 30000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_9fe9c50b5f7ebc154c5e03a40015f28e.svg) | [2-[Hydroxy-[3-[4-(4-methylphenyl)phenyl]propyl]amino]-2-oxoethyl]phosphonic acid | Ki | 30000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_3e8981171577dec0900bc295b9b7021c.svg) | 3-[3-Allyl-4-[(3-hydroxyquinuclidine-3-yl)ethynyl]phenyl]propionic acid ethyl ester | Ki | 43.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_86cc8e19a38853d18fd35d18ca4544cb.svg) | [(6-Bromo-pyridin-3-ylamino)-phosphono-methyl]-phosphonic acid | IC50 | 1400.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_d0363b47ce0131d4af6a318a56dc0940.svg) | (1S,3S,4S,5R,6R,7R)-1-[(4R,5S)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-[(E,4S,6S)-4,6-dimethyloct-2-enoyl]oxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 5.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_57bf003029751b252768daa8aa14f692.svg) | (1S,3S,4S,5R,6R,7R)-1-[(4S,5S)-4-Acetyloxy-3,5-dimethyl-6-phenylhexyl]-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 200.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b42c31622a88e7d13232a9144ed4b8f9.svg) | (1S,3S,4S,5R,6R,7R)-1-[(4S,5S)-4-Acetyloxy-3,5-dimethyl-6-phenylhexyl]-6-[(4R,6S)-4,6-dimethyloctanoyl]oxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 93.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_612319fe03dcaf2ec760e0315cf95a6e.svg) | (1S,3S,4S,5R,6R,7R)-6-[(4R,6S)-4,6-Dimethyloctanoyl]oxy-1-[(5R)-3,5-dimethyl-6-phenylhexyl]-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 14.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_2a51a1b1dc5bfc06b9dd141fccf9de4b.svg) | (1S,3S,4S,5R,6R,7R)-1-[(E,5S)-3,5-Dimethyl-6-phenylhex-3-enyl]-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 208.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_2a9a9c7ca1307da746c9af859e39f430.svg) | (1S,3S,4S,5R,6R,7R)-1-[(5R)-3,5-Dimethyl-6-phenylhexyl]-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 200.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_29a9f0c30c6f0d59644d8063abb54787.svg) | (1S,3S,4S,5R,6R,7R)-6-[(4R,6S)-4,6-Dimethyloctanoyl]oxy-4,7-dihydroxy-1-[(4S,5S)-4-hydroxy-3,5-dimethyl-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 9.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_1a2b558790815793516e4094a91cf47e.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-(decylcarbamoyloxy)-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 3.2 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_3800e04fc99b4e66740a6fba0812ba92.svg) | (6R,7R)-1-[(4S,5R)-4-Acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-dodecanoyloxy-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | IC50 | 0.96 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_162778ff96077b739efc01fb1effb463.svg) | 2-[[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]amino]-4-methylpentanoic acid | IC50 | 28.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_5601ec5bee756bc991d1bcdd81ca5ef7.svg) | 2-[1-[2-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-[2,2-dimethyl-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]propyl]-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid | IC50 | 471.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_eb3f45a6c20547d2c09f84c7fa0c421c.svg) | (2S)-2-[[(3S,6S,9As)-6-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-sulfanylpropanoyl]amino]-5-oxo-1,2,3,6,7,8,9,9a-octahydropyrrolo[1,2-a]azepine-3-carbonyl]amino]-4-methylsulfanylbutanoic acid | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_9d508d8043ea4ebdb6f448c16638bec1.svg) | (3R)-3-[2-(3-Phenylmethoxyphenyl)ethynyl]-1-azabicyclo[2.2.2]octan-3-ol | IC50 | 20000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_dbcc854b452a712db99ce07efd43916b.svg) | 3-[(4-Phenylphenyl)methyl]-1-azabicyclo[2.2.2]oct-2-ene | IC50 | 20000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_614daa8c54162b0f7847f753fc542d52.svg) | 3-[2-(4-Phenylmethoxyphenyl)ethynyl]-1-azabicyclo[2.2.2]oct-2-ene | IC50 | 250.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_c194db34b15a8170b5cca4398607b8cc.svg) | Tripotassium;4-[3-(4-fluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 17.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_62ade7e3aee0c7b5e6c091b7cdf274fc.svg) | Tripotassium;4-[3-(3-fluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 8.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_655a43d4798bad3f7f5529bd3716cead.svg) | Tripotassium;4-[3-(3,4-difluorophenoxy)phenyl]-1-phosphonatobutane-1-sulfonate | IC50 | 33.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_a8329f473567e68c5da0f278ac016ae9.svg) | 1-[2-[(1R,5R)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-(2-methylpropyl)-2-oxo-4,5-dihydro-1H-3-benzazepin-3-yl]acetyl]piperidine-4-carboxylic acid | IC50 | 220.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_588bfb73f10e93d3af821054e1386ab0.svg) | Ethyl 1-[4-[4-chloro-2-[(2-chlorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-4-carboxylate | IC50 | 0.85 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_969083ee25a4de5c5de24f4ac03296e7.svg) | 1-[4-[4-Chloro-N-(2,2-dimethylpropyl)-2-[hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid | IC50 | 1.3 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_1ea9845b510680322fefa44f942c29e2.svg) | Ethyl 1-[4-[4-chloro-N-(2,2-dimethylpropyl)-2-[hydroxy-(2-methoxyphenyl)methyl]anilino]-4-oxobutanoyl]piperidine-4-carboxylate | IC50 | 1.1 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_ccc25cbcb394f633eef749894dda0193.svg) | N-[4-Chloro-2-[(2-chlorophenyl)-hydroxymethyl]phenyl]-N-(2,2-dimethylpropyl)-4-oxo-4-piperazin-1-ylbutanamide | IC50 | 2100.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_4d10455793a83aa09936b8efd86fbef6.svg) | Ethyl 1-[5-[4-chloro-2-[(2-chlorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-5-oxopentanoyl]piperidine-4-carboxylate | IC50 | 6000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_3f85a03341e768229ba18e0dfd84a8db.svg) | Ethyl 1-[4-[4-chloro-2-[(2-chloro-4-fluorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-4-carboxylate | IC50 | 2.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_b0b567d8f84c5cf9b648c23ef50b86b1.svg) | Ethyl 1-[4-[4-chloro-2-[(2-chloro-4-fluorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-3-carboxylate | IC50 | 600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_62a2e5f4c13254b6cd1dfdba4a28f220.svg) | Ethyl 1-[4-[4-chloro-2-[2,3-dihydro-1,4-benzodioxin-5-yl(hydroxy)methyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-3-carboxylate | IC50 | 13.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_7475c11f821572cf6b008c116f80d034.svg) | 1-[4-[4-Chloro-2-[(2-chloro-4-fluorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-4-carboxylic acid | IC50 | 600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_2dc6cfb7f335e336ced7778627ee4862.svg) | 1-[4-[4-Chloro-N-(2,2-dimethylpropyl)-2-[(2-ethoxyphenyl)-hydroxymethyl]anilino]-4-oxobutanoyl]piperidine-4-carboxylic acid | IC50 | 600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/squalene-synthetase_947e470c2c5ea65310c32cb2d55ad967.svg) | 1-[4-[4-Chloro-2-[(2-chloro-3-fluorophenyl)-hydroxymethyl]-N-(2,2-dimethylpropyl)anilino]-4-oxobutanoyl]piperidine-3-carboxylic acid | IC50 | 8.4 [1] |