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Splicing factor 3B subunit 3 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
TacrolimusIC5010.9 [1], 13.8 [2]
Trichostatin AIC50577.6 [1], 611.2 [2]
LactacystinIC503481.0 [1], 10000.0 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] acetateIC501.0 [1], 1.3 [2]
[(2S,3S,6S,7R,10R)-2-[(2E,4E,6S)-7-[(2R,3S)-3-[(2S,3S)-2,3-Dihydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-7,10-dihydroxy-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] acetateIC5058.9 [1], 65.2 [2]
(4R,7R,8S,11S,12S)-4,7,8-Trihydroxy-12-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-7,11-dimethyl-oxacyclododecan-2-oneIC50307.7 [1], 418.1 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] 4-cycloheptylpiperazine-1-carboxylateIC503.2 [1], 3.6 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-2-[(2E,4E,6S)-6-methyl-7-[(2R,3R)-3-[(2S)-3-oxopentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-12-oxo-oxacyclododec-6-yl] acetateIC505.0 [1], 7.4 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] N-ethylcarbamateIC504.9 [1], 6.6 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] acetateIC503.3 [1], 4.3 [2]
(4R,7R,8S,11S,12S)-4,7,8-Trihydroxy-12-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-7,11-dimethyl-oxacyclododecan-2-oneIC502153.9 [1], 2894.2 [2]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] N-[(5S)-6-[2-[5-[(3aR,4R,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl-methylamino]ethyl-methylamino]-6-oxo-5-[[4-[3-(trifluoromethyl)diazirin-3-yl]benzoyl]amino]hexyl]carbamateIC50644.8 [1]
[(2S,3S,6S,7R,10R)-7,10-Dihydroxy-2-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-oxacyclododec-6-yl] N-[2-[2-[2-[5-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)pentanoylamino]ethoxy]ethoxy]ethyl]carbamateIC5078.4 [1]
Items per page: 1 - 10 of 13
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References

This online tool may be cited as follows

MLA

"Quest Database™ Splicing factor 3B subunit 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/splicing-factor-3b-subunit-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Splicing factor 3B subunit 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/splicing-factor-3b-subunit-3-inhibitors-ic50-ki.
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