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Solute carrier family 22 member 12 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
BenzbromaroneIC5035.0 [1]
ProbenecidIC5015000.0 [1], 50000.0 [2], 86390.0 [3], 174000.0 [4]
MorinIC502000.0 [1]
MorinKi5740.0 [1]
LesinuradIC504400.0 [1], 6700.0 [2]
6-HydroxybenzbromaroneIC50138.0 [1], 200.0 [2]
VerinuradIC5023.0 [1], 50.0 [2]
1-((6-Bromoquinolin-4-yl)thio)cyclobutane-1-carboxylic acidIC5033.0 [1], 33.7 [2]
CID 117653246IC5029.0 [1], 37.0 [2]
4-(4-Chloro-3-cyanophenoxy)-3-cyano-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC5092.0 [1]
3-Cyano-4-(4-cyano-3-fluorophenoxy)-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC5053.0 [1]
4-(3-Chloro-4-fluorophenoxy)-3-cyano-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC5019.0 [1]
3-Cyano-4-(4-cyanophenoxy)-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC5074.0 [1]
4-(2-Chloro-4-cyanophenoxy)-3-cyano-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC50183.0 [1]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyrimidin-4-ylbenzenesulfonamideIC505147.0 [1], 7674.0 [2]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyridin-2-ylbenzenesulfonamideIC50105.0 [1], 115.0 [2]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyrimidin-2-ylbenzenesulfonamideIC501823.0 [1], 3578.0 [2]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-(5-fluoropyrimidin-2-yl)benzenesulfonamideIC501954.0 [1]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyridin-3-ylbenzenesulfonamideIC50395.0 [1], 414.0 [2]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyrazin-2-ylbenzenesulfonamideIC502982.0 [1]
4-(4-Cyano-3-fluorophenoxy)-3-fluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC50382.0 [1], 1674.0 [2]
4-(3-Chloro-4-cyanophenoxy)-3-cyano-N-pyridazin-3-ylbenzenesulfonamideIC503868.0 [1]
3-Chloro-4-(4-cyano-3-fluorophenoxy)-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC50244.0 [1]
CID 86271138IC501.0 [1]
3-Cyano-4-(3-cyanophenoxy)-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC50206.0 [1]
3-Cyano-4-(3-cyano-4-fluorophenoxy)-N-(5-fluoropyridin-2-yl)benzenesulfonamideIC5057.0 [1]
CID 86294663IC5012.0 [1], 13.0 [2]
FenofibrateIC5075000.0 [1]
SulfinpyrazoneIC50100000.0 [1]
Fenofibric acidIC5011000.0 [1]
MerbaroneIC505400.0 [1]
BenzaroneIC502800.0 [1]
CID 46840946IC503500.0 [1]
5-Pyrimidinecarboxamide, hexahydro-2,4,6-trioxo-N-phenyl-IC501200.0 [1]
1-(1,5-Naphthyridin-4-ylsulfanyl)cyclobutane-1-carboxylic acidIC5010000.0 [1]
1-(1,6-Naphthyridin-5-ylsulfanyl)cyclobutane-1-carboxylic acidIC5010000.0 [1]
1-Quinazolin-4-ylsulfanylcyclobutane-1-carboxylic acidIC5010000.0 [1]
1-Quinazolin-4-yloxycyclobutane-1-carboxylic acidIC5010000.0 [1]
1-[(3-Oxo-4H-1,4-benzoxazin-5-yl)sulfanyl]cyclobutane-1-carboxylic acidIC5010000.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]ethanesulfonamideIC50713.0 [1]
N-[3-[4-(Trifluoromethyl)phenyl]pyridin-4-yl]methanesulfonamideIC504059.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]propane-1-sulfonamideIC501100.0 [1]
1,1,1-Trifluoro-N-[3-(4-methoxyphenyl)pyridin-4-yl]methanesulfonamideIC50215.0 [1]
N-[3-(3-Methoxyphenyl)pyridin-4-yl]methanesulfonamideIC509836.0 [1]
N-[3-(2-Methoxyphenyl)pyridin-4-yl]methanesulfonamideIC5020900.0 [1]
N-[3-[2-(Trifluoromethyl)phenyl]pyridin-4-yl]methanesulfonamideIC5011999.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]-4-fluorobenzenesulfonamideIC502000.0 [1]
N-[3-(4-Cyanophenyl)pyridin-4-yl]-1,1,1-trifluoromethanesulfonamideIC502.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]-1,1,1-trifluoromethanesulfonamideIC5010.0 [1]
4-Cyano-N-[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]benzenesulfonamideIC501400.0 [1]
1,1,1-Trifluoro-N-[3-(2-methoxyphenyl)pyridin-4-yl]methanesulfonamideIC50241.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]methanesulfonamideIC50261.0 [1]
N-[3-(4-Cyanophenyl)pyridin-4-yl]benzenesulfonamideIC50390.0 [1]
N-(6-Bromoquinolin-4-yl)methanesulfonamideIC503600.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]-2-methylpropane-1-sulfonamideIC50597.0 [1]
N-[3-(3-Fluorophenyl)pyridin-4-yl]methanesulfonamideIC502827.0 [1]
N-[3-(4-Cyanophenyl)pyridin-4-yl]-4-fluorobenzenesulfonamideIC504000.0 [1]
N-[3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl]benzenesulfonamideIC50127.0 [1]
N-[3-(4-Cyanophenyl)pyridin-4-yl]methanesulfonamideIC50203.0 [1]
N-(6-Bromoquinolin-4-yl)-1,1,1-trifluoromethanesulfonamideIC5083.0 [1]
2-[3-[(2,6-Dimethylphenyl)methoxy]-4-methylphenyl]acetic acidIC5080.0 [1]
(2-Ethyl-5-methoxybenzofuran-3-yl)(4-hydroxyphenyl)methanoneIC502460.0 [1]
(2-Ethyl-5-hydroxybenzofuran-3-yl)(4-hydroxyphenyl)methanoneIC502490.0 [1]
(2-Ethyl-5-methoxybenzofuran-4-yl)(4-hydroxyphenyl)methanoneIC506680.0 [1]
(2-Ethyl-5-methoxybenzofuran-7-yl)(4-hydroxyphenyl)methanoneIC5033650.0 [1]
(2-Ethyl-6-methoxybenzofuran-3-yl)(4-hydroxyphenyl)methanoneIC503920.0 [1]
(2-Ethyl-6-hydroxybenzofuran-3-yl)(4-hydroxyphenyl)methanoneIC501130.0 [1]
(2-Ethyl-6-methoxybenzofuran-4-yl)(4-hydroxyphenyl)methanoneIC5019690.0 [1]
(2-Ethyl-7-hydroxybenzofuran-4-yl)(4-hydroxyphenyl)methanoneIC503940.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxybenzofuran-3-yl)methanoneIC5042.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxybenzofuran-3-yl)methanoneIC50189.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxybenzofuran-4-yl)methanoneIC50358.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxybenzofuran-4-yl)methanoneIC5083.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxybenzofuran-7-yl)methanoneIC501440.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxybenzofuran-7-yl)-methanoneIC50287.0 [1]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-methoxybenzofuran-3-yl)-methanoneIC50111.0 [1]
(5-Bromo-2-ethyl-6-hydroxy-1-benzofuran-3-yl)-(3,5-dibromo-4-hydroxyphenyl)methanoneIC501650.0 [1]
(6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(3,5-dibromo-4-hydroxyphenyl)methanoneIC50177.0 [1]
(4,6-Dibromo-2-ethyl-5-hydroxybenzofuran-3-yl)(4-methoxyphenyl)methanoneIC5023460.0 [1]
(5,7-Dibromo-2-ethyl-6-hydroxybenzofuran-3-yl)(4-methoxyphenyl)methanoneIC50667.0 [1]
(6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(4-methoxyphenyl)methanoneIC50772.0 [1]
1-[2-(4-Cyanophenyl)phenyl]sulfanylcyclobutane-1-carboxylic acidIC5050.0 [1]
2-(3-(4-Cyanophenyl)pyridin-4-ylthio)-2-methylpropanoic acidIC5050.0 [1]
1-Quinolin-4-ylsulfanylcyclobutane-1-carboxylic acidIC50448.0 [1]
1-[6-(2-Fluorophenyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC50333.4 [1]
1-[6-[2-(Trifluoromethyl)phenyl]quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC50115.3 [1]
1-(6-Cyclopropylquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC50659.2 [1]
1-[6-(Cyanomethoxy)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC50680.2 [1]
1-[6-(Cyclopropanecarbonylamino)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC5010000.0 [1]
1-(6-Aminoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC501787.0 [1]
1-[6-(Hydroxymethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC501257.0 [1]
1-(6-Hydroxyquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC5010000.0 [1]
1-[6-(2-Cyanoethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC502757.0 [1]
1-(6-Methylquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC50343.2 [1]
1-(7-Bromoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC50129.8 [1]
1-(6-Bromoquinolin-4-yl)sulfanylcyclopropane-1-carboxylic acidIC50352.3 [1]
1-(6-Bromoquinolin-4-yl)sulfanylcyclopentane-1-carboxylic acidIC50324.3 [1]
1-[6-(Trifluoromethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC5061.2 [1]
1-(6-Methoxyquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acidIC50342.8 [1]
1-[6-(2-Methoxyethoxy)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acidIC50206.9 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Solute carrier family 22 member 12 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/solute-carrier-family-22-member-12-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Solute carrier family 22 member 12 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/solute-carrier-family-22-member-12-inhibitors-ic50-ki.
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