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Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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N-[[3-[2-(4-Fluorophenyl)ethoxy]phenyl]methyl]-2-(4-methoxyphenyl)-N-(pyridin-4-ylmethyl)acetamideIC5018200.0 [1]
4-Methoxy-N-[[3-[(3-methoxyphenyl)methoxy]phenyl]methyl]-N-(pyridin-4-ylmethyl)benzamideIC5011000.0 [1]
Chembl4164091IC5020000.0 [1]
Chembl4171968IC501700.0 [1]
4-[[2-(4-Chlorophenyl)-6-(2-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC506.0 [1]
(2S)-3-(4-Fluorophenyl)-2-[[2-(3-hydroxyphenyl)acetyl]amino]-N-[(1S)-1-phenylethyl]propanamideIC50195.0 [1]
(2S)-3-(2-Bromophenyl)-2-[[2-(4-methoxyphenyl)acetyl]amino]-N-[(1S)-1-phenylethyl]propanamideIC5090.0 [1]
4-[[2-(4-Chlorophenyl)-6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC5010000.0 [1]
4-[[6-(2-Chlorophenyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC506.0 [1]
4-[[2-(4-Chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC506.0 [1]
4-[[2-(2,4-Dichlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC506.0 [1]
4-[[2-(4-Chlorophenyl)-5-methyl-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]morpholineIC506.0 [1]
4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]morpholineIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
2-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]benzonitrileIC506.0 [1]
4-[[2-(4-Chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]morpholineIC506.0 [1]
N-[2-(4-Chlorophenyl)-3-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
[4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyridin-4-ylmethanoneIC506.0 [1]
1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyrazin-2-ylmethanoneIC506.0 [1]
[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyridazin-4-ylmethanoneIC506.0 [1]
[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-(oxan-4-yl)methanoneIC506.0 [1]
[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-(1,3-thiazol-4-yl)methanoneIC506.0 [1]
N-[2-(4-Chlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(4-Chlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(4-Chlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-methoxyethanoneIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]ethanesulfonamideIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylethanesulfonamideIC506.0 [1]
1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-hydroxy-2-methylpropan-1-oneIC506.0 [1]
1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-hydroxyethanoneIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-(1,1-dioxothiazinan-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
1-[4-[[2-(2,4-Dichlorophenyl)-6-(1,1-dioxo-1,2-thiazolidin-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylpropane-2-sulfonamideIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylpropane-1-sulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-(6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-7-ylmethyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)-N,N-dimethylimidazo[1,2-a]pyridine-6-sulfonamideIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-ethylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[(3-oxopiperazin-1-yl)methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(4-fluorobenzoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(4-fluorobenzoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(1-methylpyrazole-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[(4-hydroxypiperazin-1-yl)methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
4-[[2-(2,4-Dichlorophenyl)-6-propan-2-ylimidazo[1,2-a]pyrazin-3-yl]methyl]morpholineIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(difluoromethyl)methanesulfonamideIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(difluoromethyl)methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxane-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-methylsulfanylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-propan-2-ylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-ethylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-propan-2-ylmethanesulfonamideIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamideIC506.0 [1]
1-[4-[[2-(4-Chlorophenyl)-6-methylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanoneIC506.0 [1]
2-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-oneIC506.0 [1]
N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxane-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamideIC506.0 [1]
3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)-N-methylimidazo[1,2-a]pyridine-6-sulfonamideIC506.0 [1]
[4-[[2-(4-Chlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-(3-fluorophenyl)methanoneIC506.0 [1]
Items per page: 1 - 10 of 69
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References

This online tool may be cited as follows

MLA

"Quest Database™ Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-4-inhibitors-ic50-ki.
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