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Solute carrier family 2, facilitated glucose transporter member 3 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidineIC503000.0 [1]
1-Cyclopentyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC50120.0 [1]
1-(5-Fluoro-2-methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC50320.0 [1]
1-(3,5-Difluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC5090.0 [1]
6-[4-(2-Methoxyphenyl)piperazin-1-yl]-9-phenylpurineIC5064.0 [1]
1-(2-Methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC50110.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-b]pyridineIC504000.0 [1]
4-Methoxy-3-[4-(1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzonitrileIC5050.0 [1]
6-[4-(2-Methoxyphenyl)piperazin-1-yl]-9-phenyl-7H-purin-8-oneIC50630.0 [1]
3-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidin-1-yl]benzonitrileIC50350.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(6-methoxypyridin-3-yl)pyrazolo[3,4-d]pyrimidineIC50340.0 [1]
4-[6-(2-Methoxyphenyl)-2,6-diazaspiro[3.3]heptan-2-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC502200.0 [1]
1-(3-Methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC50170.0 [1]
4-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidin-1-yl]benzonitrileIC50200.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[4,3-c]pyridineIC502000.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(1-phenylethyl)pyrazolo[3,4-d]pyrimidineIC50950.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-pyridin-3-ylpyrazolo[3,4-d]pyrimidineIC501500.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-pyridin-4-ylpyrazolo[3,4-d]pyrimidineIC501600.0 [1]
2-[4-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzonitrileIC502050.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-7-phenylpyrazolo[3,4-d]triazineIC5010000.0 [1]
1-Phenyl-4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC5010000.0 [1]
4-[4-(3-Fluorophenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC50540.0 [1]
3-[4-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzonitrileIC5069.0 [1]
4-[4-(2-Fluoro-6-methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC501600.0 [1]
4-[4-(2-Methoxypyridin-3-yl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC50680.0 [1]
4-[4-(3-Methoxypyridin-4-yl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC501510.0 [1]
1-Phenyl-4-[4-[2-(trifluoromethoxy)phenyl]piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC5010000.0 [1]
4-[4-(3-Fluoro-2-methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5010000.0 [1]
2-Methoxy-3-[4-(1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzonitrileIC50540.0 [1]
4-[4-(4-Methoxypyridin-3-yl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5060.0 [1]
4-[4-(3-Methoxypyridin-2-yl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5070.0 [1]
2-[4-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]cyclohexan-1-olIC5010000.0 [1]
4-[4-(2-Methoxyphenyl)piperidin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5010000.0 [1]
4-[1-(2-Methoxyphenyl)piperidin-4-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC501200.0 [1]
4-[4-(2-Methoxyphenyl)-3-methylpiperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC50120.0 [1]
4-[4-(2-Methoxyphenyl)-2-methylpiperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC50480.0 [1]
4-[(1S,4S)-5-(2-Methoxyphenyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC504100.0 [1]
4-[(1R,4R)-5-(2-Methoxyphenyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5010000.0 [1]
4-[4-(3-Methoxyphenyl)piperazin-1-yl]-1-phenyl-1H-pyrazolo[3,4-d]pyrimidineIC50320.0 [1]
1-(4-Methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidineIC50170.0 [1]
4-[4-(2-Methoxyphenyl)piperazino]-1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidineIC5096.0 [1]
4-[4-(2-Fluorophenyl)piperazin-1-yl]-1-phenyl-1H-pyrazolo[3,4-d]pyrimidineIC50680.0 [1]
4-(4-(2-Methoxyphenyl)piperazin-1-yl)-1-(o-tolyl)-1H-pyrazolo[3,4-d]pyrimidineIC50250.0 [1]
4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidineIC501770.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-phenyl-1H-pyrazolo[3,4-d]pyrimidineIC50250.0 [1]
1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidineIC5046.0 [1]
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-pyridin-2-ylpyrazolo[3,4-d]pyrimidineIC50940.0 [1]
4-[4-(5-Fluoro-2-methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5010.0 [1]
7-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-phenyltriazolo[4,5-d]pyrimidineIC50430.0 [1]
2-[4-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]phenolIC5060.0 [1]
1-(3-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC50120.0 [1]
4-[4-(2-Methoxyphenyl)-1,4-diazepan-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC508.0 [1]
1-(2-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidineIC5040.0 [1]
4-Methoxy-3-[4-(1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzamideIC5037.0 [1]
3-Methoxy-4-[4-(1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]benzonitrileIC50170.0 [1]
4-[4-(4-Fluoro-2-methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidineIC5040.0 [1]
Items per page: 1 - 10 of 56
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References

This online tool may be cited as follows

MLA

"Quest Database™ Solute carrier family 2, facilitated glucose transporter member 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Solute carrier family 2, facilitated glucose transporter member 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-3-inhibitors-ic50-ki.
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