![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_26decc579f5806bc837e1ffec06d3b35.svg) | Dapagliflozin | IC50 | 1.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_6c5cf79cfd1e12ffe395e9bb109ba96e.svg) | Phlorizin | IC50 | 38.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_6c5cf79cfd1e12ffe395e9bb109ba96e.svg) | Phlorizin | Ki | 18.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_e58bb99c55ce8e62ff33cf267b66feff.svg) | T-1095A | IC50 | 5.2 [1], 11.0 [2], 50.0 [3] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_e58bb99c55ce8e62ff33cf267b66feff.svg) | T-1095A | Ki | 4.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ca91132cdb346356c5032f8ab454810e.svg) | Sotagliflozin | IC50 | 1.5 [1], 1.8 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_1309d0ac6fb2e56bcf305763a2a2e99a.svg) | Empagliflozin | IC50 | 3.1 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a23203fadda338ad2eed8d2de934b8b8.svg) | Canagliflozin | IC50 | 2.2 [1], 6.7 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ddd72d6dab08957df8632a87ff78f146.svg) | Ipragliflozin | IC50 | 7.4 [1], 8.4 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d622735169c6b923ff63ddc5f2d3441d.svg) | Sergliflozin A | IC50 | 4.8 [1], 6.25 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d622735169c6b923ff63ddc5f2d3441d.svg) | Sergliflozin A | Ki | 2.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_f0a9901f9c1613ea6197dcd67eeaa6ec.svg) | 6,8-Dichloro-4-[[5-[2-(4-chlorophenyl)ethyl]-4-(3,3,3-trifluoropropyl)-1,2,4-triazol-3-yl]methyl]-1,4-benzoxazin-3-one | IC50 | 10.0 [1], 19.0 [2], 20.0 [3] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d8472a327d6ea71e023663cb470178b9.svg) | 6,8-Dichloro-4-[[5-[2-(4-chlorophenyl)ethyl]-4-propyl-1,2,4-triazol-3-yl]methyl]-1,4-benzoxazin-3-one | IC50 | 9.0 [1], 16.0 [2], 40.0 [3] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_4706eab6ebc1a2332438699afdd19bec.svg) | Tofogliflozin | IC50 | 2.9 [1], 4.0 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a25ff7653820dc38f8486bdf797c03ea.svg) | Luseogliflozin | IC50 | 2.26 [1], 2.3 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_14c87adba121327239ad3fe179fda141.svg) | Ertugliflozin | IC50 | 0.87 [1], 2.4 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_e85b125c8aa7f3d9061dd083a7c8faaf.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(4-ethylphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 1.9 [1], 12.0 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_0cadf37ba239784783c79482e8f3f7e7.svg) | (2S,3R,4S,5S,6R)-2-[[3-[2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl]-1H-indol-4-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 24.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_300d361774b574f6d1c91126e96346c3.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(4-methoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 1.0 [1], 1.9 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_355ddf4166a82cd8969fda6cca440f4c.svg) | (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[[3-[2-(4-methoxyphenyl)ethyl]-1H-indol-4-yl]oxy]oxane-3,4,5-triol | IC50 | 163.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_2e696a5d5fc612ffb8fb1de66315a07c.svg) | (2S,3R,4R,5S,6R)-2-[5-[(4-Ethoxyphenyl)methyl]-2-hydroxyphenyl]-6-(hydroxymethyl)thiane-3,4,5-triol | IC50 | 17.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a3d460f57df07b418287a7156fdde3f0.svg) | (3S,3'R,4'S,5'S,6'R)-6-Chloro-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol | IC50 | 1.3 [1], 6.6 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a7b21918db5e5108eb308fac6825b015.svg) | 1-[2-Chloro-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-ethoxyphenyl)propan-1-one | IC50 | 0.8 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a7b21918db5e5108eb308fac6825b015.svg) | 1-[2-Chloro-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-ethoxyphenyl)propan-1-one | Ki | 1700.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_32f0db3ca964e1bd2188edc3478c4c4d.svg) | D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-hydroxyphenyl)methyl)phenyl)-, (1S)- | IC50 | 33.0 [1], 970.0 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_078fbf44433cce85506ee358d8fe7720.svg) | (3S,3'R,4'S,5'S,6'R)-5-[(4-Ethoxyphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol | IC50 | 9.6 [1], 71.0 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_5d53086094330bbccf6777c0c08c0418.svg) | O-Spiroketal glucoside | IC50 | 6.5 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_826d3c9aee9ae029caca36ad791fe0b7.svg) | (2S,3R,4R,5S,6R)-2-[3-[(4-Ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)thiane-3,4,5-triol | IC50 | 73.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_99b3eeaf1f3fe77b261af622252da02f.svg) | (2S,3R,4R,5S,6R)-2-[3-[(4-Ethoxyphenyl)methyl]-4-methylphenyl]-6-(hydroxymethyl)thiane-3,4,5-triol | IC50 | 2.29 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_725e37e1b7388148a9f949e7976d5270.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(furan-2-yl)-1,3-thiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 0.72 [1], 1.75 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_20c53d7302164a8a8d3ea69feee4c3a8.svg) | (2R,3R,4S,5S,6R)-2-[3-[(4-Ethylphenyl)methyl]indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 7.1 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d2fdde763b021796de570257916d7063.svg) | (2S,3R,4S,5S,6R)-2-[(4-Benzyl-5-propan-2-yl-1H-pyrazol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 2020.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_244edbf86dd22a1263b6956af5900b04.svg) | (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[[4-[(4-hydroxyphenyl)methyl]-5-propan-2-yl-1H-pyrazol-3-yl]oxy]oxane-3,4,5-triol | IC50 | 285.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_077e1536fc6488c2c91a24aebccbcd2d.svg) | (2S,3R,4R,5S,6R)-2-[3-[(4-Ethylphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 5.1 [1], 10.0 [2] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_44131feaa5d4719adf5a2e5637dda1bd.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-quinolin-2-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 562.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_1aa555cd4004a844f1e9db73b1a4b8f0.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pyrazin-2-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 4.06 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_7bb40b854a23ba37a6562dd2900ea5d5.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pyridazin-4-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 190.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_b04de17722deee7d9386037a762db127.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(furan-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 7.03 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_b40caf7526600af2a677e840c4f04b78.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(furan-3-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 17.7 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_44d7a1155fefaa10adac9cacbae93efe.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(3-methylfuran-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 106.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_6953e1adb863c542efcffccb16d25c38.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(5-methylfuran-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 58.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_42ae70f358d679831c63a5a87bd0ba3b.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(5-phenylfuran-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 10.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_c521334d4895006734cca5e15c8c1d5e.svg) | (2S,3R,4R,5S,6R)-2-[3-[[5-(1-Benzofuran-2-yl)-1,3,4-thiadiazol-2-yl]methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 249.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_8b88ae03dea95a9143b5aaa4274f01a9.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(5-methyl-1,2-oxazol-3-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 257.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ee804286af3e1c187873c298261f3df2.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(1-methylpyrrol-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 119.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_669ef7f84c0973231b84d329d0ae2e06.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 14.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_dc6576f330a9c8155b3cf77c708dec63.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-thiophen-3-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 3.51 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_f941f9b08829dabe14cbe30e341a8dd2.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(3-methylthiophen-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 762.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_402e3ac6e32fbff8b4256fb02fa31a93.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(3-chlorothiophen-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 712.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ddbe3d1a4c3e4508cabc558369054d99.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(5-chlorothiophen-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 18.2 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ecac6bdc041d853868e47271e40b2301.svg) | (2S,3R,4R,5S,6R)-2-[3-[[5-(1-Benzothiophen-2-yl)-1,3,4-thiadiazol-2-yl]methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 44.5 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_5ab1e14f9fa7924e26e95c88d4cdd425.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(1,3-thiazol-4-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 21.8 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_00846c112d3d851f15cde8db880be5d5.svg) | (3R,4R,5S,6R)-2-[4-Chloro-3-[(5-cyclohexyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 542.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_54e442943e61e68c018930ad876d1114.svg) | (3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 103.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_5a211c03e453d97c2aec736573c7599e.svg) | (3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(4-propylphenyl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 24.9 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_6d1a1eaedaad8874ff1d66a381f6494e.svg) | (3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 45.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_f16ad63f80d347c4926124c0f18bbce1.svg) | (3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 53.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_58c4c30fc73c28cc0bd0b0e734503d69.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-propyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 214.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_de307d1603f4982382c6a78093f2d2f4.svg) | (2S,3R,4R,5S,6R)-2-[3-[(5-Butyl-1,3,4-thiadiazol-2-yl)methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 379.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_54e32dab081771f89d4fcec4613b90dd.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pentyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 353.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_3543e4bd2d5b750854661060a2d04acf.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-heptyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 122.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_591c492be5569745d22ef21b3679612f.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-methoxy-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 146.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_370fc7bab6864e6764b02903f200d03a.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 10.9 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_58810eb7bae96d6f05d94f8d7865b569.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 155.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_8cf035567006697abc66e73d13ffbda8.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(2,2,2-trifluoroethyl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 758.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_51fa827f8df616747b3d17fefede7a29.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-cyclopentyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 445.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_03c86bba00841fb8c14b004a3d6ff2d4.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-phenyl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 16.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_116905124177d45a167c876c64478db3.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 126.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_6dff752f15593e1bb29b176c962c5405.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-pyridin-2-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 30.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_7a3368a0be59d30dba93c91be9625ed7.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(6-methylpyridin-2-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 638.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d8b5075178007a3828f6f5716d8c0dc4.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(6-methylpyridin-3-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 97.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_c60029cee2652d32026c30d634f63f9f.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[5-(2-methylpyridin-4-yl)-1,3,4-thiadiazol-2-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 36.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_f82a14845b10da43e0e2a29ff4d708dc.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(5-isoquinolin-3-yl-1,3,4-thiadiazol-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 81.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_243534f63aa1c65ee77d17cbbb9e8a0b.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-chloropyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 202.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ad3cf0abfcbefa487a669ff47a9f76d2.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-ethoxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 43.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_2afac2a3fc880d23e2112d8330253e5a.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-propoxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 70.8 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_d9c6c73932c03cece8a4daf860b06a75.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-propan-2-yloxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 110.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_3ee9b225b8164e92e4245a3aca10f272.svg) | (2S,3R,4R,5S,6R)-2-[3-[(6-Butoxypyridazin-3-yl)methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 109.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ebe40cc9c2170050043143fe28d231b7.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(2-methylpropoxy)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 435.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_155e0b719a0aef9b12ab2d08e919bd03.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-pentoxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 17.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_77afaa00cdd4454bb882ce2e0bd5f29e.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-hexoxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 17.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_e1c1d79016c167f19dfd0f2e0446b713.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-cyclohexyloxypyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 111.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_16c9cfab7d65d2a45a01af6f90b88eeb.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(oxan-4-yloxy)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 77.6 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_a823daa5d3767a6ca76308a5b5049430.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-methylsulfanylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 13.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_ccd771ecd83ed69b682b67e3ee9e28a8.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-ethylsulfanylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 71.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_e17a843cf9cf3261d9394ffa5696a737.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-phenylsulfanylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 1870.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_7d05ce3cad914f199507494693d31237.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-methylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 293.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_f9671dcc6c3898e8430210abbf0d2808.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-ethylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 131.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_cd60bd8db647f3f19a8244563a93b9e6.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-propylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 237.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_c65fd557cf2ff593e923a56e2b4bb8c3.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-propan-2-ylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 259.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_c5d691372655f3bbb8a597a6854f9ea3.svg) | (2S,3R,4R,5S,6R)-2-[3-[(6-Butylpyridazin-3-yl)methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 356.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_9508a9ca0d5459fcb4cebfd241e1f4b8.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(2-methylpropyl)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 811.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_b9fb0ff06bebc7a92cb276b999a913dd.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-pentylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 134.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_32eaa87025c4dca1d747eecdabbe2074.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(2-phenylethynyl)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 176.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_dd3b34ad00d98cc4214d5cabec037c1e.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(furan-2-yl)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 64.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_11c9bd26ab2fad7faee4a9dcb0bb4f51.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(furan-3-yl)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 61.3 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_91e033bb98ec2a26094864ce21bb5b4d.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-thiophen-2-ylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 71.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_78280d1202cc78d03649d70f36a29679.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-thiophen-3-ylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 75.4 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_acc29d7f1e3b258efd99b252c8577131.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[6-(5-methylthiophen-2-yl)pyridazin-3-yl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 168.0 [1] |
![](https://images.aatbio.com/dataset/ic50/sodium-glucose-cotransporter-2_5fcb4d813a53118989fb2a742fd65583.svg) | (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(6-phenylpyridazin-3-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | IC50 | 222.0 [1] |