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Sodium-dependent proline transporter Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
Biphenyl-4-yl-(4-phenyl-piperazin-1-yl)-methanoneIC501480.0 [1]
Biphenyl-4-yl-[4-(4-fluoro-phenyl)-piperazin-1-yl]-methanoneIC503440.0 [1]
4-Phenylphenyl 4-pyrimidin-2-ylpiperazinyl ketoneIC50280.0 [1]
4-Phenylphenyl 4-(2-pyridyl)piperazinyl ketoneIC50160.0 [1]
[4-(3-Chlorophenyl)phenyl]-(3-pyrimidin-2-yl-3,8-diazabicyclo[3.2.1]octan-8-yl)methanoneIC5018.0 [1]
(3-Phenylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC501880.0 [1]
[4-(5-Chlorothiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50150.0 [1]
[4-(4-Methylthiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5034.0 [1]
[4-(5-Methylthiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5061.0 [1]
[4-(2-Phenylethoxy)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC501020.0 [1]
[4-(Benzylamino)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50870.0 [1]
2-Phenyl-N-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]acetamideIC5010000.0 [1]
Benzyl N-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]carbamateIC5010000.0 [1]
(2-Tert-butyl-4-pyrimidin-2-ylpiperazin-1-yl)-[4-(3-chlorophenyl)phenyl]methanoneIC50700.0 [1]
[4-(3-Chlorophenyl)phenyl]-(2,2-dimethyl-4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5053.0 [1]
[4-(3-Chlorophenyl)phenyl]-(2,6-dimethyl-4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5024.0 [1]
[4-(3-Chlorophenyl)phenyl]-[2-(hydroxymethyl)-4-pyrimidin-2-ylpiperazin-1-yl]methanoneIC5076.0 [1]
1-[4-(3-Chlorophenyl)benzoyl]-4-pyrimidin-2-ylpiperazine-2-carboxylic acidIC50128.0 [1]
1-[4-(3-Chlorophenyl)benzoyl]-N,N-dimethyl-4-pyrimidin-2-ylpiperazine-2-carboxamideIC50392.0 [1]
[4-(4-Chlorophenyl)phenyl]-[(2R)-2-methyl-4-pyrimidin-2-ylpiperazin-1-yl]methanoneIC5057.0 [1]
[4-(3-Chlorophenyl)phenyl]-(4-pyrimidin-2-yl-1,4-diazepan-1-yl)methanoneIC5089.0 [1]
4-(3-Chlorophenyl)-N-methyl-N-[2-[methyl(pyrimidin-2-yl)amino]ethyl]benzamideIC50586.0 [1]
[4-(3-Chlorophenyl)phenyl]-(5-pyrimidin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl)methanoneIC501340.0 [1]
[4-(3-Chlorophenyl)phenyl]-(8-pyrimidin-2-yl-3,8-diazabicyclo[3.2.1]octan-3-yl)methanoneIC5027.0 [1]
4-(4-Chlorophenyl)piperazinyl 4-phenylphenyl ketoneIC5010000.0 [1]
[4-(4-Fluorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50260.0 [1]
(3-Methyl-4-pyrimidin-2-ylpiperazin-1-yl)-(4-phenylphenyl)methanoneIC50477.0 [1]
[4-(4-Methylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5034.0 [1]
[4-(3-Chlorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5036.0 [1]
(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[3-(trifluoromethyl)phenyl]phenyl]methanoneIC5071.0 [1]
[4-(4-Ethylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5077.0 [1]
[4-(4-Methylpyrimidin-2-yl)piperazin-1-yl]-(4-phenylphenyl)methanoneIC50270.0 [1]
(4-Pyridin-2-ylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC507080.0 [1]
(4-Phenylphenyl)-(4-pyrazin-2-ylpiperazin-1-yl)methanoneIC501300.0 [1]
[4-(4-Methoxyphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50230.0 [1]
4-[4-(4-Pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]benzonitrileIC50190.0 [1]
(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[2-(trifluoromethyl)phenyl]phenyl]methanoneIC501260.0 [1]
[4-(4-Chlorophenyl)phenyl]-[(2S)-2-methyl-4-pyrimidin-2-ylpiperazin-1-yl]methanoneIC5021.0 [1]
(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[4-(trifluoromethyl)phenyl]phenyl]methanoneIC5076.0 [1]
[4-(4-Chlorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC5052.0 [1]
[4-(2-Methylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50653.0 [1]
(4-Phenylphenyl)-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanoneIC502180.0 [1]
(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[3-(trifluoromethoxy)phenyl]phenyl]methanoneIC5073.0 [1]
(4-Phenylphenyl)-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanoneIC50146.0 [1]
3-[4-(4-Pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]benzonitrileIC50190.0 [1]
(4-Cyclohexylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC507010.0 [1]
2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidineIC501950.0 [1]
(4-Pyrimidin-2-ylpiperazin-1-yl)-(4-pyrrol-1-ylphenyl)methanoneIC502230.0 [1]
Phenyl-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]methanoneIC502700.0 [1]
2-{4-[4-(1H-Imidazol-1-yl)benzoyl]piperazin-1-yl}pyrimidineIC5010000.0 [1]
2-(4-{[1,1'-Biphenyl]-2-carbonyl}piperazin-1-yl)pyrimidineIC506010.0 [1]
(3'-Chloro-biphenyl-4-yl)-(5-Pyrimidin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneIC5036.0 [1]
[1,1'-Biphenyl]-4-yl(4-(pyridazin-3-yl)piperazin-1-yl)methanoneIC505000.0 [1]
(4-Phenylmethoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanoneIC50270.0 [1]
Items per page: 1 - 10 of 54
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References

This online tool may be cited as follows

MLA

"Quest Database™ Sodium-dependent proline transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/sodium-dependent-proline-transporter-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Sodium-dependent proline transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sodium-dependent-proline-transporter-inhibitors-ic50-ki.
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