Sodium-dependent neutral amino acid transporter B(0)AT2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Loratadine	IC50	4000.0 [1]
	Desloratadine	IC50	172000.0 [1]
	Rupatadine	IC50	40000.0 [1]
	Respatadine	IC50	54800.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-phenylethanone	IC50	16100.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]butan-1-one	IC50	4900.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]propan-1-one	IC50	36000.0 [1]
	N-Methyldesloratadine	IC50	80000.0 [1]
	Propyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	4600.0 [1]
	4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-N-ethylpiperidine-1-carboxamide	IC50	35000.0 [1]
	13-Chloro-2-(1-propylsulfonylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene	IC50	80000.0 [1]
	Propan-2-yl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	16800.0 [1]
	Tert-butyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	80000.0 [1]
	Prop-2-enyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	4900.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-methylpropan-1-one	IC50	41500.0 [1]
	(E)-1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]but-2-en-1-one	IC50	5000.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-3-methylbutan-1-one	IC50	10800.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]pentan-1-one	IC50	3400.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]hexan-1-one	IC50	5200.0 [1]
	3-Amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]propan-1-one	IC50	18700.0 [1]
	(2R)-2-Amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-3-methylbutan-1-one	IC50	39100.0 [1]
	(2R)-2-Amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-4-methylpentan-1-one	IC50	7700.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-methoxyethanone	IC50	26400.0 [1]
	S-Ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carbothioate	IC50	5300.0 [1]
	Benzyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	80000.0 [1]
	Phenyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	80000.0 [1]
	2-Methylpropyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate	IC50	7800.0 [1]
	Desloratadine N-Carboxylic Acid Methyl Ester	IC50	19600.0 [1]
	3-Methoxy Loratadine	IC50	4500.0 [1]
	1-[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-cyclohexylethanone	IC50	5700.0 [1]
	2-Amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]ethanone	IC50	22900.0 [1]
	3-Hydroxy Loratadine	IC50	17600.0 [1]
	2-Cyano Loratadine	IC50	80000.0 [1]
	4-Cyano Loratadine	IC50	80000.0 [1]
	2-Hydroxymethyl Loratadine	IC50	80000.0 [1]
	2-Methoxycarbonyl Loratadine	IC50	12400.0 [1]
	4-Hydroxymethyl Loratadine	IC50	18300.0 [1]
	Isoloratadine	IC50	14800.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 38 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Sodium-dependent neutral amino acid transporter B(0)AT2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/sodium-dependent-neutral-amino-acid-transporter-b-0-at2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ Sodium-dependent neutral amino acid transporter B(0)AT2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sodium-dependent-neutral-amino-acid-transporter-b-0-at2-inhibitors-ic50-ki.
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