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Sodium- and chloride-dependent taurine transporter Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2,4-Dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
N-((1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
N-((4-(Morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
3,6-Dichloro-2-fluoro-N-((1-(propylsulfonyl)-4-(pyridine-2-yL)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((4-(6-methylpyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Chloro-N-((4-(6-methylpyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,6-Dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
(S)-2,4-Dichloro-N-(1-(1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)ethyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((4-(cyclopropylmethyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((1-(cyclopropylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Amino-6-chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((4-(4-methylpyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Chloro-N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
4-((2,4-Dichlorobenzamido)methyl)-N,N-dimethyl-1-(propylsulfonyl)piperidine-4-carboxamideIC5030000.0 [1]
4-((2,4-Dichlorobenzamido)methyl)-N-ethyl-1-(propylsulfonyl)piperidine-4-carboxamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-[3-(dimethylamino)pyrrolidine-1-carbonyl]-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,4-Dichloro-N-((4-(cyclopropanecarbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-(4-methylpiperazine-1-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
N-[[4-(Morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]-2-(trifluoromethoxy)benzamideIC5030000.0 [1]
2-Chloro-4-fluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
4-[[(2,4-Dichlorobenzoyl)amino]methyl]-N-[(3-methyloxetan-3-yl)methyl]-1-propylsulfonylpiperidine-4-carboxamideIC5030000.0 [1]
N-[[4-(3-Aminoazetidine-1-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]-2,4-dichlorobenzamideIC5030000.0 [1]
2-Fluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]-4-(trifluoromethyl)benzamideIC5030000.0 [1]
4-Fluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]-2-(trifluoromethyl)benzamideIC5030000.0 [1]
N-((4-(Morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)propionamideIC5030000.0 [1]
N-((4-(Morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)cyclopropanecarboxamideIC5030000.0 [1]
3-Chloro-2,6-difluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2-Chloro-6-fluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,4-Dichloro-5-fluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,6-Difluoro-N-[[4-(morpholine-4-carbonyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
N-[(1S)-1-(1-Propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)ethyl]-2-(trifluoromethoxy)benzamideIC5030000.0 [1]
2-Chloro-3,5-difluoro-N-[(1S)-1-(1-propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)ethyl]benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-(oxan-2-ylmethyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-(2-methoxyethyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-(2-hydroxycyclohexyl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[1-(2-fluoropropylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
2-Fluoro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
N-((4-(4-Methylpyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
N-((4-(6-Methoxypyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2-Chloro-N-[[4-(6-methoxypyridin-2-yl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
3-Methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
N-[(1-Propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)methyl]-2-(trifluoromethyl)benzamideIC5030000.0 [1]
N-[(1-Propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)methyl]-2-(trifluoromethoxy)benzamideIC5030000.0 [1]
2-Chloro-N-[[4-(4-methylpyridin-2-yl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
N-((4-(6-Methylpyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
2,4-Dichloro-N-[[4-(6-methoxypyridin-2-yl)-1-propylsulfonylpiperidin-4-yl]methyl]benzamideIC5030000.0 [1]
4-Chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
3-Chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)benzamideIC5030000.0 [1]
3,4-Dichloro-N-[(1-propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)methyl]benzamideIC5030000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Sodium- and chloride-dependent taurine transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/sodium-and-chloride-dependent-taurine-transporter-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Sodium- and chloride-dependent taurine transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sodium-and-chloride-dependent-taurine-transporter-inhibitors-ic50-ki.
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