logo
AAT Bioquest

 
search
logo
AAT Bioquest
Image Gallery
Contact us
Company
Telephone:1-408-733-1055
Fax:1-408-733-1304
Hours:Monday to Friday
8:30 - 17:30 PST (GMT-8)
Location:5775 W Las Positas Blvd.
Pleasanton, CA, 94588
USA

Email us
Sales:sales@aatbio.com
Technical Support:support@aatbio.com
Website:websupport@aatbio.com
General Inquiries:info@aatbio.com
Order info
United States of America
Telephone:1-408-733-1055
Fax:1-408-733-1304
Email:sales@aatbio.com
Purchase Order:sales@aatbio.com

International
Click here to see all available distributors
 
search
calculatorCalculator

Sigma opioid receptor Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
HaloperidolIC504.0 [1]
HaloperidolKi1.8 [1]
1,3-Di-o-tolylguanidineIC5031.0 [1]
1,3-Di-o-tolylguanidineKi28.8 [1]
(+)-PentazocineKi2.1 [1], 2.7 [2], 3.77 [3], 6.1 [4], 152.0 [5]
alpha-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanolIC5071.0 [1], 83.0 [2], 112.0 [3], 120.0 [4]
alpha-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanolKi71.0 [1], 164.0 [2], 265.0 [3]
N-(2-(3,4-Dichlorophenyl)ethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamineKi0.7 [1]
NalorphineIC50735.0 [1]
RimcazoleIC50450.0 [1], 588.84 [2], 780.0 [3], 1400.0 [4], 1480.0 [5]
RimcazoleKi680.0 [1], 820.0 [2], 908.0 [3]
PhencyclidineIC50560.0 [1], 868.0 [2], 1000.0 [3], 1050.0 [4]
PhencyclidineKi1090.0 [1], 1767.0 [2]
1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazineKi5.3 [1]
S1RAKi17.0 [1]
PentazocineKi36.5 [1], 83.1 [2], 110.0 [3]
(S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-olIC50140.0 [1], 213.8 [2], 310.0 [3], 420.0 [4]
(S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-olKi490.0 [1]
(R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-olIC5028.0 [1], 32.0 [2], 43.0 [3], 436.52 [4]
(R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-olKi64.0 [1]
BuspironeIC5036.31 [1], 263.0 [2]
BuspironeKi212.0 [1], 2427.0 [2]
1,3-DiphenylguanidineIC50397.0 [1], 400.0 [2]
1,3-DiphenylguanidineKi713.0 [1]
SiramesineKi17.0 [1]
N,N'-Bis(4-methylphenyl)guanidineIC50535.0 [1]
N,N'-Bis(4-methylphenyl)guanidineKi3.1 [1], 164.0 [2]
(10As)-2-[3-[benzyl(methyl)amino]propyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dioneIC503.9 [1], 650.0 [2]
(10As)-2-[3-[benzyl(methyl)amino]propyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dioneKi4.5 [1]
((R)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-amineKi17.0 [1], 21.8 [2], 28.0 [3], 39.0 [4]
NaloxoneIC50100000.0 [1]
NaloxoneKi100000.0 [1]
ApomorphineIC5010000.0 [1], 31000.0 [2]
VanoxerineIC501.0 [1], 43.0 [2]
VanoxerineKi318.0 [1]
FenpropimorphKi0.01 [1], 0.08 [2], 17.3 [3]
[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-cyclohexyl)-amineKi1.3 [1], 7.78 [2]
(-)-cis-(1S,2R)-U-50488 TartrateIC50194.0 [1]
(-)-cis-(1S,2R)-U-50488 TartrateKi118.0 [1], 221.0 [2]
5-Bromo-N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2,3-dimethoxybenzamideKi12900.0 [1]
N-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2-methoxy-5-methylbenzamideKi3078.0 [1]
(1S,13R)-1,13-Dimethyl-10-prop-2-enyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-olKi124.0 [1], 150.0 [2], 169.0 [3]
(+)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-cyclohexyl)-amineKi6.0 [1], 18.68 [2]
((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-amineKi10.8 [1], 22.0 [2]
3-Chloro-6-methylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-olIC5010.47 [1], 21.1 [2], 10000.0 [3]
(10Ar)-2-[3-[benzyl(methyl)amino]propyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dioneIC501000.0 [1]
(10Ar)-2-[3-[benzyl(methyl)amino]propyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dioneKi7.1 [1]
Unii-G7fms28pydIC50285.0 [1]
Unii-G7fms28pydKi232.0 [1]
1,2-Bis(3-methylphenyl)guanidineIC5043.0 [1], 59.0 [2], 84.0 [3]
Guanidine, N,N'-bis(3-ethylphenyl)-IC508.0 [1], 8.3 [2], 30.0 [3]
Methyl-((S)-1-methyl-2-phenyl-ethyl)-phenethyl-amineKi4.8 [1], 6.6 [2], 16.4 [3]
((R)-1-Methyl-2-phenyl-ethyl)-phenethyl-amineKi13.6 [1], 60.0 [2], 61.0 [3]
N,N''-Bis(2-ethylphenyl)guanidineIC5013.8 [1], 14.0 [2], 44.0 [3]
1,3-Bis(4-bromophenyl)guanidineIC5033.0 [1], 350.0 [2], 540.0 [3]
N,N'-Bis(2-methoxyphenyl)guanidineIC501990.0 [1], 2200.0 [2], 3800.0 [3]
(9S,13S)-10-Benzyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-olKi0.67 [1], 1710.0 [2]
(1R,13S)-1,13-Dimethyl-10-pentyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-olKi0.29 [1], 3.8 [2], 10.5 [3]
1,2-Bis(2-iodophenyl)guanidineIC5013.0 [1], 14.0 [2], 16.0 [3]
2,2-Dimethyl-N-[1-(2-piperidin-1-ylethyl)pyrazolo[3,4-d]pyrimidin-4-yl]propanamideKi51.0 [1], 51.29 [2]
[1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pentyl]-propyl-amine; hydrochlorideIC501.8 [1], 200.0 [2], 210.0 [3]
ProgesteroneKi260.0 [1], 1284.0 [2]
MorphineKi10000.0 [1], 100000.0 [2]
TamoxifenKi8.71 [1], 35.0 [2]
FluoxetineIC50851.14 [1]
FluoxetineKi210.0 [1]
ClozapineKi8500.0 [1]
AmiodaroneKi1.0 [1], 41.0 [2]
DizocilpineIC5010000.0 [1]
SertralineKi29.3 [1], 57.0 [2]
RaloxifeneKi38.0 [1], 286.0 [2]
SulpirideIC5010000.0 [1]
ClomipheneKi8.0 [1], 12.0 [2]
trans-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamideKi696.0 [1], 1270.0 [2]
ProadifenIC501584.89 [1]
ProadifenKi17.0 [1]
AstemizoleKi944.0 [1], 1258.93 [2]
ClemastineKi10.0 [1], 14.0 [2]
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-allyl-6,11-dimethyl-Ki59.7 [1], 429.0 [2]
3-(1-Propyl-3-piperidinyl)phenolIC5076.0 [1]
3-(1-Propyl-3-piperidinyl)phenolKi78.5 [1]
BuflomedilKi912.2 [1], 1290.0 [2]
TenocyclidineIC501100.0 [1], 2060.0 [2]
(-)-VesamicolKi26.0 [1]
1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazineIC5017.0 [1]
CaramiphenKi15.5 [1], 26.0 [2]
NE 100 hydrochlorideIC501.3 [1], 85.0 [2]
PolyhexamethyleneguanidineIC50750.0 [1], 800.0 [2]
1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazineKi6.3 [1], 9.2 [2]
Reduced haloperidolKi14.34 [1]
AptiganelIC502535.0 [1], 2540.0 [2]
4-Phenyl-1-(4-phenylbutyl)piperidineKi0.8 [1], 1.0 [2]
NaluzotanKi100.0 [1], 2000.0 [2]
1'-Benzyl-1-methoxyspiro[1H-2-benzofuran-3,4'-piperidine]Ki1.14 [1]
1'-Benzyl-3-methoxyspiro[isochroman-1,4'-piperidine]Ki1.29 [1]
1,4-DibenzylpiperazineKi5.81 [1]
sigma-LIGAND-1IC5036.0 [1], 43.0 [2]
13-Methyl-10-prop-2-enyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-olKi3600.0 [1], 4300.0 [2]
1-Benzyl-4-(4-methoxybenzyl)piperazineKi0.47 [1]
SpipethianeKi0.5 [1], 0.59 [2]
Items per page: 1 - 10 of 100
⟨⟩

References

This online tool may be cited as follows

MLA

"Quest Database™ Sigma opioid receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/sigma-opioid-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Sigma opioid receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sigma-opioid-receptor-inhibitors-ic50-ki.
BibTeXEndNoteRefMan