Sigma intracellular receptor 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine	Ki	0.34 [1], 2.51 [2]
	Haloperidol	Ki	16.0 [1]
	Chloroquine	Ki	501.19 [1]
	Hydroxychloroquine	Ki	1000.0 [1]
	Moclobemide	Ki	200.0 [1]
	Astemizole	Ki	95.5 [1]
	Clemastine	Ki	25.12 [1]
	Ibogaine	Ki	90.4 [1]
	Siramesine	Ki	0.12 [1]
	Eprobemide	Ki	200.0 [1]
	3-(4-Methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole	Ki	794.33 [1]
	CID 11301655	Ki	2000.0 [1]
	N-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2-methoxy-5-methylbenzamide	Ki	10.33 [1]
	4-Chloro-N-[2-(pyrrolidin-1-yl)ethyl]benzamide	Ki	200.0 [1]
	Unii-G7fms28pyd	Ki	231.0 [1]
	N-[4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butyl]-2-(2-(18F)fluoranylethoxy)-5-iodo-3-methoxybenzamide	Ki	0.26 [1]
	4-Chloro-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide	Ki	200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-tert-butylbenzamide	Ki	200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-(trifluoromethyl)benzamide	Ki	98.0 [1]
	N-[2-[Benzyl(methyl)amino]ethyl]-4-cyanobenzamide	Ki	170.0 [1]
	N-[2-[Benzyl(methyl)amino]ethyl]-4-nitrobenzamide	Ki	1400.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3,5-dichlorobenzamide	Ki	48.0 [1]
	4-Chloro-N-[3-[methyl(2-phenylethyl)amino]propyl]benzamide	Ki	200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3,4-dichlorobenzamide	Ki	59.0 [1]
	Chembl4173950	Ki	170.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-butylbenzamide	Ki	49.0 [1]
	N-[4-[Benzyl(methyl)amino]butyl]-4-chlorobenzamide	Ki	20.0 [1]
	4-[4-[1-[4-[1-(6-Aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid	Ki	1200.0 [1]
	N-[4-(4-Benzylpiperidin-1-yl)butyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	8.4 [1]
	N-[2-(4-Benzylpiperidin-1-yl)ethyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	76.1 [1]
	N-[3-(4-Benzylpiperidin-1-yl)propyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	22.3 [1]
	N-[4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	23.0 [1]
	N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	23.8 [1]
	N-[5-(4-Benzylpiperidin-1-yl)pentyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	24.0 [1]
	N-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	16.2 [1]
	N-[5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)pentyl]-4-nitro-3-(trifluoromethyl)aniline	Ki	25.5 [1]
	N-[2-[Benzyl(methyl)amino]ethyl]-2,3-dichlorobenzamide	Ki	110.0 [1]
	[(1R,5R)-9-(6-Aminohexyl)-9-azabicyclo[3.3.1]nonan-3-yl] N-(2-methoxy-5-methylphenyl)carbamate	Ki	5.19 [1]
	4-Chloro-N-[3-(1,3-dihydroisoindol-2-yl)propyl]benzamide	Ki	350.0 [1]
	4-Chloro-N-[3-(4-methylpiperazin-1-yl)propyl]benzamide	Ki	200.0 [1]
	1-Cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperazine hydrochloride	Ki	12.6 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3-chlorobenzamide	Ki	340.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-methoxybenzamide	Ki	1200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3-methoxybenzamide	Ki	1200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-nitrobenzamide	Ki	360.0 [1]
	Chembl4174984	Ki	95.0 [1]
	4-Chloro-N-[3-(pyrrolidin-1-yl)propyl]benzamide	Ki	200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3-(dimethylamino)benzamide	Ki	321.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-2-bromobenzamide	Ki	1200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-2-chlorobenzamide	Ki	1200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-chlorobenzamide	Ki	190.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-3-bromobenzamide	Ki	350.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-cyanobenzamide	Ki	1200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-2,3-dichlorobenzamide	Ki	310.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-bromo-2-fluorobenzamide	Ki	200.0 [1]
	N-{3-[Benzyl(methyl)amino]propyl}-4-fluorobenzamide	Ki	470.0 [1]
	Chembl4164330	Ki	200.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-propylbenzamide	Ki	160.0 [1]
	Chembl4176123	Ki	850.0 [1]
	Chembl4164424	Ki	400.0 [1]
	N-[3-[Benzyl(methyl)amino]propyl]-4-bromobenzamide	Ki	160.0 [1]
	3-Ethyl-N-[(1S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxobenzimidazole-1-carboxamide	Ki	32.0 [1]
	4,5,6,7-Tetrahydro-4-(2-(morpholin-4-yl)ethyl)-1-phenyl-1H-indazole	Ki	113.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 63 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Sigma intracellular receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/sigma-intracellular-receptor-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Sigma intracellular receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sigma-intracellular-receptor-2-inhibitors-ic50-ki.
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