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SHC-transforming protein 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC50248000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-ethylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5019000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-propylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5025700.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-prop-2-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5026600.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-butylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC508900.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-but-3-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC506000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-benzylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5018900.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-but-2-ynylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5083000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(3-methylbutyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5017000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(4-fluorobutyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5040000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(4,4,4-trifluorobutyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5023000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(2-methoxyethyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5056000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(4-methylpentyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5029000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-pentylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5010000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-pent-4-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5016000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-pent-2-ynylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5017000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(2-ethoxyethyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5033000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(2-ethylsulfanylethyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5034000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-hexylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5020000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-hex-5-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5014000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-(4-cyanobutyl)amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5044000.0 [1]
[4-[(2S)-2-[Acetyl(prop-2-enyl)amino]-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5041000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC50189000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-prop-2-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5048000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-1-(but-3-enylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC50165000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-4-methyl-1-oxo-1-(prop-2-enylamino)pentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5091000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-prop-2-enylamino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC50353000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-4-methyl-1-oxo-1-(prop-2-enylamino)pentan-2-yl]-prop-2-enylamino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5081000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-4-methyl-1-oxo-1-(prop-2-enylamino)pentan-2-yl]amino]-2-oxoethyl]-prop-2-enylamino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5047000.0 [1]
[4-[(2S)-2-[Acetyl(prop-2-enyl)amino]-3-[[(2S)-5-amino-1-[[2-[[(2S)-4-methyl-1-oxo-1-(prop-2-enylamino)pentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC50450000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-(but-3-enylamino)-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5084000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[but-3-enyl-[(2S)-1-[[(2S)-1-(but-3-enylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5089000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[but-3-enyl-[2-[[(2S)-1-[[(2S)-1-(but-3-enylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC508000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[[2-[but-3-enyl-[(2S)-1-(but-3-enylamino)-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5084000.0 [1]
[4-[(2S)-2-Acetamido-3-[[(2S)-5-amino-1-[but-3-enyl-[2-[[(2S)-1-(but-3-enylamino)-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphateIC5014000.0 [1]
Items per page: 1 - 10 of 35
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References

This online tool may be cited as follows

MLA

"Quest Database™ SHC-transforming protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/shc-transforming-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ SHC-transforming protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/shc-transforming-protein-1-inhibitors-ic50-ki.
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