 | Serotonin | IC50 | 262.0 [1] |
 | Clozapine | IC50 | 17.0 [1], 20.0 [2] |
| Clozapine | Ki | 10.0 [1] |
 | 5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide | IC50 | 2.0 [1] |
| 5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide | Ki | 0.8 [1] |
 | 4-Amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide | IC50 | 26.3 [1] |
| 4-Amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide | Ki | 44.7 [1] |
 | 2-Ethyl-5-methoxy-N,N-dimethyltryptamine | IC50 | 85.0 [1] |
 | Methiothepin | IC50 | 2.4 [1], 4.7 [2], 11.0 [3], 127.0 [4] |
| Methiothepin | Ki | 0.4 [1], 0.9 [2], 1.0 [3], 4.1 [4] |
 | Intepirdine | IC50 | 2.8 [1] |
 | 4-Amino-N-[2,6-bis(methylamino)pyridin-4-yl]benzenesulfonamide | Ki | 14.8 [1] |
 | 1-(4-Aminophenylsulfonyl)-3-methyl-1H-indole | IC50 | 300.0 [1], 320.0 [2] |
 | Latrepirdine | IC50 | 890.0 [1], 1160.0 [2] |
| Latrepirdine | Ki | 26.0 [1], 33.88 [2], 34.0 [3] |
 | Chlorpromazine | Ki | 4.0 [1], 26.0 [2], 50.0 [3], 50.12 [4], 60.0 [5] |
 | Aripiprazole | Ki | 89.0 [1], 90.0 [2], 199.53 [3], 574.0 [4], 1000.0 [5] |
 | Ziprasidone | Ki | 20.0 [1], 61.0 [2], 63.1 [3], 76.0 [4] |
 | N,N-Dimethyl-5-methoxytryptamine | Ki | 13.0 [1], 16.0 [2], 70.0 [3], 78.0 [4] |
 | 2-(1-((6-Chloroimidazo(2,1-b)(1,3)thiazol-5-yl)sulfonyl)-1H-indol-3-yl)ethylamine | Ki | 2.0 [1] |
 | 4-(2-Bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine | IC50 | 3.2 [1] |
| 4-(2-Bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine | Ki | 1.0 [1] |
 | 2-(1-Benzyl-1H-indol-3-yl)-N,N-dimethylethanamine | Ki | 6.0 [1] |
 | 1-[1-(Benzenesulfonyl)indol-3-yl]-N,N-dimethylmethanamine | IC50 | 800.0 [1], 880.0 [2] |
| 1-[1-(Benzenesulfonyl)indol-3-yl]-N,N-dimethylmethanamine | Ki | 3.0 [1], 3.1 [2] |
 | CID 44155874 | IC50 | 4.61 [1], 30.0 [2] |
| CID 44155874 | Ki | 1.2 [1], 2.0 [2] |
 | 3-(Benzenesulfonyl)-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine | IC50 | 5.0 [1] |
| 3-(Benzenesulfonyl)-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine | Ki | 0.2 [1], 0.26 [2] |
 | 4-Bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide | IC50 | 16.0 [1] |
| 4-Bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide | Ki | 5.0 [1], 5.01 [2] |
 | 5-Methyl-2-methylsulfanyl-3-phenylsulfonyl-6,7,8,9-tetrahydropyrazolo[1,5-a]quinazoline | IC50 | 0.95 [1], 6.0 [2], 16.8 [3], 32.0 [4] |
| 5-Methyl-2-methylsulfanyl-3-phenylsulfonyl-6,7,8,9-tetrahydropyrazolo[1,5-a]quinazoline | Ki | 0.44 [1] |
 | 9-Methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline | IC50 | 1.46 [1], 7.8 [2] |
| 9-Methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline | Ki | 0.68 [1] |
 | N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide | Ki | 0.7 [1], 0.72 [2], 0.78 [3], 0.8 [4] |
 | Idalopirdine | Ki | 0.83 [1] |
 | 5-Chloro-N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]naphthalene-2-sulfonamide | Ki | 0.2 [1], 0.7 [2] |
 | N-(3-(2-Dimethylaminoethyl)-1H-indol-5-yl)-6-chloroimidazo(2,1-b)thiazole-5-sulfonamide | Ki | 2.2 [1] |
 | 1-(Phenylsulfonyl)-4-(1-piperazinyl)-1h-indole | Ki | 0.3 [1], 0.32 [2], 1.0 [3] |
 | 3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]pyrimidin-4-ylideneamine | IC50 | 4.0 [1] |
| 3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]pyrimidin-4-ylideneamine | Ki | 3.98 [1] |
 | 5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine | IC50 | 510.0 [1], 1000.0 [2] |
| 5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine | Ki | 237.0 [1], 561.0 [2] |
 | Indole, 3-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl- | Ki | 60.0 [1], 80.0 [2], 89.0 [3] |
 | 4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-5-ol | Ki | 7.2 [1], 7.94 [2] |
 | 5-Chloro-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide | Ki | 0.6 [1], 0.63 [2] |
 | 1-(Phenylsulfonyl)-4-[2-(dimethylamino)ethyl]-1H-indole | Ki | 1.5 [1] |
 | [3-(2-Dimethylamino-ethyl)-5-methoxy-indol-1-yl]-phenyl-methanone | Ki | 18.0 [1], 25.0 [2], 25.12 [3] |
 | N-[3-[(8As)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide | Ki | 0.79 [1], 0.8 [2] |
 | 1-(2-Bromophenyl)sulfonyl-3-(1-methylpyrrolidin-3-yl)indole | IC50 | 53.3 [1] |
| 1-(2-Bromophenyl)sulfonyl-3-(1-methylpyrrolidin-3-yl)indole | Ki | 1.0 [1] |
 | 4-[3-(2-Dimethylamino-ethyl)-indole-1-sulfonyl]-phenylamine | Ki | 0.8 [1] |
 | 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | IC50 | 158.0 [1] |
| 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Ki | 1.2 [1], 2.0 [2], 3.0 [3] |
 | 1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole | IC50 | 8.5 [1] |
| 1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole | Ki | 1.4 [1], 50.0 [2] |
 | 1-(Benzenesulfonyl)-3-[[(2S)-1-methylpyrrolidin-2-yl]methyl]indole | IC50 | 81.4 [1] |
| 1-(Benzenesulfonyl)-3-[[(2S)-1-methylpyrrolidin-2-yl]methyl]indole | Ki | 1.7 [1], 5.0 [2] |
 | 2-(Methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]quinazoline | IC50 | 1.18 [1], 7.5 [2], 35.0 [3] |
| 2-(Methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]quinazoline | Ki | 0.55 [1] |
 | 10-(Benzenesulfonyl)-11-methylsulfanyl-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene | IC50 | 0.99 [1], 6.0 [2], 27.0 [3] |
| 10-(Benzenesulfonyl)-11-methylsulfanyl-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene | Ki | 0.46 [1] |
 | 2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazoline | IC50 | 17.2 [1], 98.5 [2], 479.0 [3] |
| 2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazoline | Ki | 7.97 [1] |
 | Haloperidol | Ki | 1083.0 [1], 5000.0 [2], 6000.0 [3] |
 | 2-Methyl-5-hydroxytryptamine | Ki | 46.0 [1], 400.0 [2] |
 | 1-Naphthylpiperazine | Ki | 100.0 [1], 104.0 [2], 120.0 [3] |
 | Benzenesulfonamide, 4-iodo-N-(4-methoxy-3-(4-methyl-1-piperazinyl)phenyl)- | IC50 | 19.0 [1] |
| Benzenesulfonamide, 4-iodo-N-(4-methoxy-3-(4-methyl-1-piperazinyl)phenyl)- | Ki | 2.51 [1] |
 | 3-((3-Fluorophenyl)sulfonyl)-N,N-dimethyl-1H-pyrrolo(2,3-b)pyridine-1-ethanamine | Ki | 4.8 [1], 4.9 [2] |
 | {2-[5-Methoxy-1-(naphthalene-1-sulfonyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine | Ki | 0.9 [1] |
 | (6-Methoxy-2,3,4,9-tetrahydro-1H-carbazol-4-ylmethyl)-dimethyl-amine | Ki | 168.0 [1] |
 | {2-[7-Methoxy-1-(naphthalene-2-sulfonyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine | Ki | 5.0 [1] |
 | 4-[3-(2-Dimethylamino-ethyl)-5-methoxy-indole-1-sulfonyl]-phenylamine | Ki | 0.6 [1], 2.0 [2] |
 | 2-[3-(3-Fluorophenyl)sulfonylindol-1-yl]-N,N-dimethylethanamine | Ki | 10.3 [1], 13.0 [2] |
 | 1-[9-(Benzenesulfonyl)-6-methoxy-1,2,3,4-tetrahydrocarbazol-4-yl]-N,N-dimethylmethanamine | Ki | 1.5 [1], 2.3 [2] |
 | 1-Benzenesulfonyl-3-piperidin-3-yl-1H-indole | IC50 | 0.0 [1] |
| 1-Benzenesulfonyl-3-piperidin-3-yl-1H-indole | Ki | 1.0 [1], 2.0 [2] |
 | {2-[5-Methoxy-1-(naphthalene-2-sulfonyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine | Ki | 1.6 [1], 9.8 [2] |
 | 6-Chloro-N-[1-(2-pyrrolidin-1-ylethyl)indol-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide | IC50 | 135.0 [1] |
| 6-Chloro-N-[1-(2-pyrrolidin-1-ylethyl)indol-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide | Ki | 9.8 [1] |
 | N-[3-[[(2S)-1-Methylpyrrolidin-2-yl]methyl]-1H-indol-5-yl]-3-(trifluoromethyl)benzenesulfonamide | IC50 | 14.1 [1] |
| N-[3-[[(2S)-1-Methylpyrrolidin-2-yl]methyl]-1H-indol-5-yl]-3-(trifluoromethyl)benzenesulfonamide | Ki | 12.0 [1] |
 | (R)-3-(1-Methyl-2-pyrrolidinylmethyl)-1-phenylsulfonylindole | IC50 | 0.6 [1] |
| (R)-3-(1-Methyl-2-pyrrolidinylmethyl)-1-phenylsulfonylindole | Ki | 0.3 [1], 8.0 [2] |
 | 1-Benzenesulfonyl-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole | IC50 | 43.0 [1] |
| 1-Benzenesulfonyl-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole | Ki | 2.0 [1] |
 | 2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimidazole | Ki | 16.0 [1] |
 | 1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)methanone | Ki | 13.0 [1], 15.0 [2] |
 | 5-Fluoro-3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-indole | IC50 | 18.0 [1] |
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