Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Tautomycetin	IC50	62.0 [1], 400.0 [2]
	Okadaic acid	IC50	7.0 [1]
	[(3R,4S,5R,8S,9S,12R)-12-[(2S,3S,6R,8S,9R)-3,9-Dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undecan-2-yl]-5,9-dihydroxy-4-methoxy-2,8-dimethyl-7-oxotridecan-3-yl] (3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoate	IC50	22.0 [1]
	(5R,8S,11R,15S,18S,19S,22R)-15-Benzyl-1,5,18,19-tetramethyl-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid	IC50	900.0 [1]
	(2S,4R,4As,6R,8aR)-2-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,2'-oxolane]-4-ol	IC50	1000000.0 [1]
	(2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2'R,4R,4As,6R,8aR)-4-hydroxy-2-(hydroxymethyl)-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoic acid	IC50	304.0 [1]
	(E,8S,10S,13S,14S,17R,18S,19R)-4-Ethyl-3,13,17-trihydroxy-19-[(3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoyl]oxy-8,10,14,18-tetramethyl-15-oxoicos-4-enoic acid	IC50	640.0 [1]
	(2E,4E,8S,10S,13S,14S,17R,18S,19R)-4-Ethyl-13,17-dihydroxy-19-[(3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoyl]oxy-8,10,14,18-tetramethyl-15-oxoicosa-2,4-dienoic acid	IC50	520.0 [1]
	(2E,4E,6S,8R,10S,13S,14S,17R,18S,19R)-4-Ethyl-6,13,17-trihydroxy-19-[(3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoyl]oxy-8,10,14,18-tetramethyl-15-oxoicosa-2,4-dienoic acid	IC50	44000.0 [1]
	(2E,4E,6R,8R,10S,13S,14S,17R,18S,19R)-4-Ethyl-6,13,17-trihydroxy-19-[(3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoyl]oxy-8,10,14,18-tetramethyl-15-oxoicosa-2,4-dienoic acid	IC50	800.0 [1]
	(2E,4E,8R,10S,13S,14S,17R,18S,19R)-4-Ethyl-13,17-dihydroxy-19-[(3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoyl]oxy-8,10,14,18-tetramethyl-6,15-dioxoicosa-2,4-dienoic acid	IC50	920.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 11 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/serine-threonine-protein-phosphatase-2a-catalytic-subunit-alpha-isoform-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-phosphatase-2a-catalytic-subunit-alpha-isoform-inhibitors-ic50-ki.
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