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Serine/threonine-protein kinase TNNI3K Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-(Dimethylamino)-N-methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC5050.0 [1]
N-Methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC5080.0 [1]
4-(Dimethylamino)-N-methyl-3-(5H-pyrrolo[3,2-d]pyrimidin-4-ylamino)benzenesulfonamideIC5025.0 [1], 500.0 [2]
3-{[6,7-Bis(methyloxy)-4-quinazolinyl]amino}-4-(dimethylamino)-N-methylbenzenesulfonamideIC5025.0 [1], 100.0 [2]
3-[(5,7-Dimethoxyquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC5010.0 [1]
4-(Dimethylamino)-N-methyl-3-[(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]benzenesulfonamideIC501.6 [1], 10.0 [2]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-(trifluoromethoxy)benzenesulfonamideIC5032.0 [1], 320.0 [2]
3-[(5-Bromo-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)amino]-N-Methyl-4-(Morpholin-4-Yl)benzenesulfonamideIC506.3 [1], 10.0 [2]
4-(Dimethylamino)-N-methyl-3-(thieno[3,2-d]pyrimidin-4-ylamino)benzenesulfonamideIC50200.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-(methylamino)benzenesulfonamideIC502500.0 [1]
3-((6-Aminoquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamideIC5032.0 [1]
4-(Dimethylamino)-3-[(6-methoxyquinazolin-4-yl)amino]-N-methylbenzenesulfonamideIC5079.0 [1]
4-(Dimethylamino)-N-methyl-3-(quinazolin-4-ylamino)benzenesulfonamideIC50200.0 [1]
4-(Dimethylamino)-N-methyl-3-[[6-(methylamino)quinazolin-4-yl]amino]benzenesulfonamideIC5050.0 [1]
4-Chloro-3-[[6-(4-chloroanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC50130.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5025.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC5079.0 [1], 80.0 [2]
4-Chloro-N-methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC5020.0 [1]
N-Methyl-3-(9h-Purin-6-Ylamino)benzenesulfonamideIC50500.0 [1]
3-(5-Methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino-N-methylbenzenesulfonamideIC5040.0 [1]
3-[(5-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-N-methylbenzenesulfonamideIC5032.0 [1]
3-[(5-Bromo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-N-methylbenzenesulfonamideIC5032.0 [1]
3-[(5-Fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-N-methylbenzenesulfonamideIC50126.0 [1], 130.0 [2]
N-Methyl-3-[(5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]benzenesulfonamideIC5040.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-methylsulfanylbenzenesulfonamideIC50400.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-4-fluoro-N-methylbenzenesulfonamideIC50200.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-4-methoxy-N-methylbenzenesulfonamideIC5050.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N,4-dimethylbenzenesulfonamideIC50160.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC5079.0 [1], 80.0 [2]
N,4-Dimethyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC50630.0 [1]
3-[[5-(3-Chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC5063.0 [1]
N-Methyl-4-(methylamino)-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC506300.0 [1]
4-(Dimethylamino)-N-methyl-3-[(5-methylpyrrolo[3,2-d]pyrimidin-4-yl)amino]benzenesulfonamideIC5016.0 [1], 50.0 [2]
3-[(7-Ethoxy-6-methoxyquinazolin-4-yl)amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5013.0 [1], 50.0 [2]
N-Methyl-3-[[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5013.0 [1], 79.0 [2]
3-[[7-(3-Methoxypropoxy)quinazolin-4-yl]amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5025.0 [1], 320.0 [2]
4-(Dimethylamino)-3-[[7-(3-methoxypropoxy)quinazolin-4-yl]amino]-N-methylbenzenesulfonamideIC5010.0 [1], 25.0 [2]
4-(Dimethylamino)-N-methyl-3-[[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]benzenesulfonamideIC5010.0 [1], 25.0 [2]
3-[(5,7-Dimethoxyquinazolin-4-yl)amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5010.0 [1], 13.0 [2]
3-[(6,7-Dimethoxyquinazolin-4-yl)amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC5025.0 [1], 160.0 [2]
N-Methyl-4-(2,2,2-trifluoroethoxy)-3-[(5,6,7-trimethoxyquinazolin-4-yl)amino]benzenesulfonamideIC5010.0 [1], 63.0 [2]
N-Methyl-3-[(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-4-morpholin-4-ylbenzenesulfonamideIC507.9 [1], 13.0 [2]
3-[(5-Bromo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC500.7 [1], 10.0 [2]
3-[(6-Bromo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC5040.0 [1]
3-[(6-Bromo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-N-methyl-4-morpholin-4-ylbenzenesulfonamideIC50126.0 [1], 398.0 [2]
N-Methyl-4-morpholin-4-yl-3-[[6-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzenesulfonamideIC5010.0 [1], 16.0 [2]
4-(Dimethylamino)-N-methyl-3-[[6-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzenesulfonamideIC5013.0 [1], 16.0 [2]
3-[[6-[(5-Chloropyridin-2-yl)amino]pyrimidin-4-yl]amino]-4-ethylsulfonyl-N-methylbenzenesulfonamideIC508.0 [1], 10.0 [2]
N-Methyl-4-morpholin-4-yl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC5040.0 [1], 100.0 [2]
3-(2-Fluoro-9H-purine-6-yl)amino-N-methylbenzenesulfonamideIC503200.0 [1]
3-(9-Methyl-9H-purine-6-yl)amino-N-methylbenzenesulfonamideIC5025000.0 [1]
3-(2-Amino-9H-purine-6-yl)amino-N-methylbenzenesulfonamideIC508000.0 [1]
3-(2-Chloro-9H-purine-6-yl)amino-N-methylbenzenesulfonamideIC5016000.0 [1]
N-Methyl-3-[(7-methylpyrrolo[2,3-d]pyrimidin-4-yl)amino]benzenesulfonamideIC5025000.0 [1]
N-Methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-ylamino)benzenesulfonamideIC508000.0 [1]
N-Methyl-3-[(6-oxo-5,7-dihydropyrrolo[2,3-d]pyrimidin-4-yl)amino]benzenesulfonamideIC50400.0 [1]
3-(9H-Purine-6-yl)amino-N-ethylbenzenesulfonamideIC502000.0 [1]
3-(9H-Purine-6-yl)aminobenzenesulfonamideIC5040000.0 [1]
N-Hydroxy-3-(7H-purin-6-ylamino)benzenesulfonamideIC5020000.0 [1]
3-(9H-Purine-6-yl)aminophenylethyl sulfoneIC506300.0 [1]
2-Methyl-5-(9H-purine-6-yl)amino-N-methylbenzenesulfonamideIC5013000.0 [1]
3-(9H-Purine-6-yl)amino-4-methyl-N-methylbenzenesulfonamideIC50500.0 [1]
N-Methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]benzenesulfonamideIC505000.0 [1]
N-Methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)benzenesulfonamideIC5016000.0 [1]
4-(Ethylamino)-N-methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC502500.0 [1]
4-(Dimethylamino)-N-methyl-3-(pyrido[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC505000.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-(propylamino)benzenesulfonamideIC501600.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-pyrrolidin-1-ylbenzenesulfonamideIC501300.0 [1]
4-Methoxy-N-methyl-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC50100.0 [1]
N-Methyl-4-(propylamino)-3-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzenesulfonamideIC502500.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-4-(ethylamino)-N-methylbenzenesulfonamideIC503200.0 [1]
N-Methyl-3-[[2-(3-methylanilino)pyridin-4-yl]amino]benzenesulfonamideIC505000.0 [1]
N-Methyl-3-[methyl-[6-(3-methylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC508000.0 [1]
3-[[6-(N,3-Dimethylanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC502000.0 [1]
N-Methyl-3-[[6-(2-methylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC501300.0 [1]
N-Methyl-3-[[2-(3-methylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC50630.0 [1]
3-[[6-(2-Methoxyanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC503200.0 [1]
3-[(6-Methoxy-7-propan-2-yloxyquinazolin-4-yl)amino]-N-methyl-4-(2,2,2-trifluoroethoxy)benzenesulfonamideIC50130.0 [1]
N-Methyl-3-(9H-pyrimido[4,5-b]indol-4-ylamino)benzenesulfonamideIC50100.0 [1]
4-(Dimethylamino)-N-methyl-3-(9H-pyrimido[4,5-b]indol-4-ylamino)benzenesulfonamideIC5050.0 [1]
3-[(6-Chloroquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC50400.0 [1]
4-(Dimethylamino)-N-methyl-3-[[7-(methylamino)quinazolin-4-yl]amino]benzenesulfonamideIC5040.0 [1]
3-[(7-Aminoquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamideIC5063.0 [1]
3-[[4-(4-Chloroanilino)-1,3,5-triazin-2-yl]amino]-N-methylbenzenesulfonamideIC5050.0 [1]
3-[(6-Anilinopyrimidin-4-yl)amino]-N-methylbenzenesulfonamideIC5063.0 [1]
N-Methyl-3-[[6-(3-nitroanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC50500.0 [1]
3-[[6-(4-Methoxyanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC50160.0 [1]
N-Methyl-3-[[6-(3-methylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC5032.0 [1]
3-[[6-(3-Chloroanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC5079.0 [1]
N-Methyl-3-[[6-(methylamino)pyrimidin-4-yl]amino]benzenesulfonamideIC50800.0 [1]
N-Methyl-3-[[6-[3-(methylsulfamoyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamideIC5079.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-4-ethoxy-N-methylbenzenesulfonamideIC5050.0 [1]
3-[[6-(4-Chloroanilino)pyrimidin-4-yl]amino]-N-methyl-4-[methyl(2,2,2-trifluoroethyl)amino]benzenesulfonamideIC5040.0 [1]
4-Amino-3-[[6-(4-chloroanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC50800.0 [1]
N-Methyl-3-[[6-(4-methylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC5079.0 [1]
3-[[6-(3-Methoxyanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC5063.0 [1]
3-[[6-(2-Fluoroanilino)pyrimidin-4-yl]amino]-N-methylbenzenesulfonamideIC50630.0 [1]
N-Methyl-3-[[6-(3-methylsulfonylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC50200.0 [1]
N-Methyl-3-[[6-(4-methylsulfonylanilino)pyrimidin-4-yl]amino]benzenesulfonamideIC5079.0 [1]
N-Methyl-3-[[4-(3-methylanilino)-1,3,5-triazin-2-yl]amino]benzenesulfonamideIC5020.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Serine/threonine-protein kinase TNNI3K Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-tnni3k-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Serine/threonine-protein kinase TNNI3K Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-tnni3k-inhibitors-ic50-ki.
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