Serine/threonine-protein kinase TAO1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-[[2-(4-Bromophenoxy)acetyl]amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	50.0 [1]
	4-Heptoxy-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	N-[1-Oxo-1-(1,2,3,4-tetrahydronaphthalen-2-ylamino)propan-2-yl]-4-phenylmethoxybenzamide	IC50	50.0 [1], 500.0 [2]
	2-[[2-(4-Phenylmethoxyphenoxy)acetyl]amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	50.0 [1]
	4-Heptyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1], 500.0 [2]
	4-Hexoxy-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	4-Hexyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	4-Butoxy-N-[1-oxo-1-(1,2,3,4-tetrahydronaphthalen-2-ylamino)propan-2-yl]benzamide	IC50	50.0 [1], 500.0 [2]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-pentylbenzamide	IC50	50.0 [1]
	2-Cyclopentyl-N-[2-oxo-1-pyridin-3-yl-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-2-phenylacetamide	IC50	50.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-pentoxybenzamide	IC50	50.0 [1]
	N-[1-Oxo-1-(1,2,3,4-tetrahydronaphthalen-2-ylamino)propan-2-yl]-4-pentoxybenzamide	IC50	50.0 [1], 500.0 [2]
	N-[2-(3-Chlorophenyl)ethyl]-5-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridine-6-carboxamide	IC50	50.0 [1], 500.0 [2]
	3,5-Dimethyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylmethoxybenzamide	IC50	50.0 [1], 500.0 [2]
	4-(4-Ethylphenyl)-N-[1-oxo-1-(1,2,3,4-tetrahydronaphthalen-2-ylamino)propan-2-yl]benzamide	IC50	50.0 [1]
	(2S)-N-Benzhydryl-2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-3-phenylmethoxypropanamide	IC50	500.0 [1], 5000.0 [2]
	2-[[2-(4-Tert-butylphenoxy)acetyl]amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	500.0 [1], 5000.0 [2]
	N-[(2S)-4-Methyl-1-oxo-1-(1,2,3,4-tetrahydronaphthalen-1-ylamino)pentan-2-yl]-4-pentoxybenzamide	IC50	500.0 [1], 5000.0 [2]
	(2S)-2-[(4-Butoxyphenyl)carbamoylamino]-N-(2-phenylethyl)-3-phenylmethoxypropanamide	IC50	50.0 [1], 5000.0 [2]
	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-(1,2,3,4-tetrahydronaphthalen-1-ylamino)propan-2-yl]-5,6-dimethoxy-2,3-dihydro-1H-indole-2-carboxamide	IC50	50.0 [1], 500.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-2-[4-(5-pyridin-2-ylpyrimidin-2-yl)phenoxy]acetamide	IC50	50.0 [1]
	N-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepine-3-carboxamide	IC50	50.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide	IC50	50.0 [1]
	N-[3-Oxo-3-[[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]amino]-1-phenylpropyl]benzamide	IC50	500.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenoxybenzamide	IC50	50.0 [1]
	2-[(6-Methoxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl 3-(benzoylamino)-3-phenylpropanoate	IC50	50.0 [1]
	N-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-3-(3-ethoxypropyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide	IC50	50.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]naphthalene-2-carboxamide	IC50	500.0 [1], 5000.0 [2]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-(trifluoromethoxy)benzamide	IC50	500.0 [1]
	2-[(4-Phenylphenyl)methylamino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	(2S)-2-Amino-1-N-(4-butylphenyl)-2-N-[(3,4-dichlorophenyl)methyl]pyrrolidine-1,2-dicarboxamide	IC50	50.0 [1], 500.0 [2]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-4-ylamino)ethyl]benzamide	IC50	500.0 [1]
	2-[[2-(3-Methoxyphenoxy)acetyl]amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	500.0 [1]
	2-[[2-(4-Chlorophenoxy)acetyl]amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	N-[4-Methyl-1-oxo-1-(1,2,3,4-tetrahydronaphthalen-1-ylamino)pentan-2-yl]-4-phenylbenzamide	IC50	500.0 [1], 5000.0 [2]
	4-(4-Ethylphenyl)-N-[2-oxo-2-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]ethyl]benzamide	IC50	50.0 [1]
	(2S)-2-Amino-2-N-[(3,4-dichlorophenyl)methyl]-1-N-(4-propan-2-ylphenyl)pyrrolidine-1,2-dicarboxamide	IC50	50.0 [1], 500.0 [2]
	N-[3-[[2-[(6-Hydroxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]amino]-3-oxo-1-phenylpropyl]benzamide	IC50	50.0 [1]
	N-[2-(Cyclohexylamino)-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	4-Butyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	500.0 [1], 5000.0 [2]
	2-[(4-Phenylphenyl)carbamoylamino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylpiperazine-1-carboxamide	IC50	5000.0 [1]
	2-[4-(2-Naphthalen-1-ylethylsulfonyl)piperazin-1-yl]-N-pyridin-2-ylacetamide	IC50	50.0 [1]
	N-[2-Oxo-2-(5,6,7,8-tetrahydronaphthalen-1-ylamino)ethyl]quinoline-3-carboxamide	IC50	5000.0 [1]
	N-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-2-[[2-[4-(trifluoromethoxy)phenoxy]acetyl]amino]acetamide	IC50	500.0 [1]
	4-Hexoxy-N-[1-oxo-1-(1,2,3,4-tetrahydronaphthalen-2-ylamino)propan-2-yl]benzamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	IC50	5000.0 [1]
	N-[3-[(6-Hydroxy-1,3-benzothiazol-2-yl)amino]-3-oxo-1-phenylpropyl]benzamide	IC50	5000.0 [1]
	N-[2-(Benzylamino)-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	N-[2-Oxo-1-pyridin-3-yl-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-(1,2,4-triazol-1-yl)benzamide	IC50	50.0 [1]
	N-[2-[(3,4-Dichlorophenyl)methylamino]-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(5,6,7,8-tetrahydronaphthalen-1-ylamino)ethyl]quinoline-6-carboxamide	IC50	5000.0 [1]
	2-[[3,5-Bis(trifluoromethyl)phenyl]carbamoylamino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	N-[2-(2,3-Dihydro-1,4-benzodioxin-3-ylmethylamino)-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	N-[3-[[2-[(6-Methoxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]amino]-3-oxo-1-phenylpropyl]benzamide	IC50	50.0 [1]
	4-Cyclohexyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	4-(4-Ethylphenyl)-N-[2-(naphthalen-1-ylamino)-2-oxoethyl]benzamide	IC50	50.0 [1]
	4-(4-Ethylphenyl)-N-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]benzamide	IC50	5000.0 [1]
	2-Cyclopentyl-N-[2-oxo-2-[[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]amino]-1-pyridin-3-ylethyl]-2-phenylacetamide	IC50	5000.0 [1]
	2-[[2-(4-Bromophenoxy)acetyl]amino]-N-[(3,4-dichlorophenyl)methyl]acetamide	IC50	50.0 [1], 500.0 [2]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]quinoline-3-carboxamide	IC50	5000.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzamide	IC50	5000.0 [1]
	4-(4-Ethylphenyl)-N-methyl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	5000.0 [1]
	4-Butoxy-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	500.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(1-phenylethylamino)ethyl]benzamide	IC50	500.0 [1], 5000.0 [2]
	4-Imidazol-1-yl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	500.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-[[2-(trifluoromethyl)phenyl]methylamino]ethyl]benzamide	IC50	50.0 [1], 5000.0 [2]
	N-[3-[[2-[(4-Methyl-1,3-thiazol-2-yl)amino]-2-oxoethyl]amino]-3-oxo-1-phenylpropyl]benzamide	IC50	5000.0 [1]
	Tert-butyl 4-[[2-[[4-(4-ethylphenyl)benzoyl]amino]acetyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate	IC50	5000.0 [1]
	4-(1,3-Oxazol-5-yl)-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-piperidin-1-ylbenzamide	IC50	500.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(2-phenylethylamino)ethyl]benzamide	IC50	5000.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-(1-phenylpropylamino)ethyl]benzamide	IC50	500.0 [1], 5000.0 [2]
	2-Amino-4-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-N-(3-ethoxypropyl)benzene-1,4-dicarboxamide	IC50	5000.0 [1]
	N-[2-Oxo-1-pyridin-3-yl-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenyldiazenylbenzamide	IC50	500.0 [1]
	4-Morpholin-4-yl-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	5000.0 [1]
	N-[3-[[2-(1,3-Benzothiazol-2-ylamino)-2-oxoethyl]amino]-3-oxo-1-phenylpropyl]benzamide	IC50	50.0 [1]
	5,6-Dimethoxy-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-1H-indole-2-carboxamide	IC50	500.0 [1]
	2-[2-(4-Phenylphenyl)ethylcarbamoylamino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	N-[3-[[2-[(6-Methoxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]amino]-3-oxopropyl]benzamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-3-piperidin-1-ylpropanamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylmethoxybenzamide	IC50	50.0 [1]
	3-Acetamido-N-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]-3-phenylpropanamide	IC50	5000.0 [1]
	4-(4-Ethylphenyl)-N-[2-[(2-methylphenyl)methylamino]-2-oxoethyl]benzamide	IC50	50.0 [1]
	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]quinoline-6-carboxamide	IC50	500.0 [1]
	N-(6-Methoxy-1,3-benzothiazol-2-yl)-4-[[2-(4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-3-yl)acetyl]amino]butanamide	IC50	50.0 [1], 500.0 [2]
	2-[(3-Ethylphenyl)carbamoylamino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	IC50	5000.0 [1]
	4-(4-Ethylphenyl)-N-[2-oxo-2-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]ethyl]benzamide	IC50	5000.0 [1]
	N-[2-Oxo-2-(5,6,7,8-tetrahydronaphthalen-1-ylamino)ethyl]-4-piperidin-1-ylbenzamide	IC50	5000.0 [1]
	4-Hydroxy-N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]benzamide	IC50	50.0 [1], 500.0 [2]
	2-[[2-(5,6-Dimethyl-4-oxothieno[2,3-d]pyrimidin-3-yl)acetyl]amino]-N-(6-methoxy-1,3-benzothiazol-2-yl)acetamide	IC50	50.0 [1], 500.0 [2]
	4-Butoxy-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-(1,2,3,4-tetrahydronaphthalen-1-ylamino)propan-2-yl]benzamide	IC50	50.0 [1], 500.0 [2]
	N-[3-Oxo-3-[[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]amino]-1-phenylpropyl]benzamide	IC50	5000.0 [1]
	N-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-4-(4-ethylphenyl)benzamide	IC50	5000.0 [1]
	(2S)-2-[[(E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]amino]-3-(1H-indol-3-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide	IC50	50.0 [1], 500.0 [2]
	N-[3-[[2-[(5-Methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]-2-oxoethyl]amino]-3-oxo-1-phenylpropyl]benzamide	IC50	50.0 [1]
	CID 59604787	IC50	10000.0 [1]
	5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide	IC50	420.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase TAO1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-tao1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Serine/threonine-protein kinase TAO1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-tao1-inhibitors-ic50-ki.
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