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Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanolIC50110.0 [1]
CID 71458575IC500.11 [1]
N-(3-Chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amineIC50280.0 [1]
4-({4-[3-(Piperidin-1-Ylcarbonyl)phenyl]pyrimidin-2-Yl}amino)benzenesulfonamideIC50450.0 [1]
4-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamideIC50370.0 [1]
1-Methyl-3-[4-[4-[2-(3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]ureaIC500.05 [1]
N-(3-Methoxyphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amineIC501100.0 [1]
1-Methyl-3-[4-[4-[2-(4-methyl-3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]ureaIC500.05 [1]
1-Methyl-3-[4-[4-[2-[4-methyl-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]ureaIC500.05 [1]
3-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamideIC5011.0 [1]
4-(2-Morpholin-4-ylpyridin-4-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amineIC50250.0 [1]
3-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzonitrileIC5080.0 [1]
1-[4-[4-[2-[3-(Diethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylureaIC500.2 [1]
3-[[4-[2-(4-Methylpiperazin-1-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamideIC50310.0 [1]
3-[[4-(2-Piperidin-1-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamideIC503.0 [1]
1-[4-[4-[2-[3-(Diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylureaIC500.2 [1]
3-[[4-[2-(3-Hydroxypropylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamideIC5022.0 [1]
N-(4-Chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amineIC501000.0 [1]
4-(2-Morpholin-4-ylpyridin-4-yl)-N-phenylpyrimidin-2-amineIC501500.0 [1]
3-[[4-[2-(Diethylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamideIC503.0 [1]
3-[[4-[2-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamideIC5025.0 [1]
1-Methyl-3-[4-[4-[2-[3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]ureaIC500.1 [1]
1-[4-[4-[2-[3-(Dimethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylureaIC500.05 [1]
3-[[4-[2-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamideIC506.0 [1]
1-[4-[4-[2-[4-Chloro-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylureaIC500.05 [1]
1-[4-[4-[2-[4-Chloro-3-(dimethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylureaIC500.05 [1]
N-(3-Methylphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amineIC50330.0 [1]
Items per page: 1 - 10 of 27
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References

This online tool may be cited as follows

MLA

"Quest Database™ Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-smg1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 20). Quest Database™ Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-smg1-inhibitors-ic50-ki.
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