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Serine/threonine-protein kinase MST4 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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EntrectinibIC5010000.0 [1]
Nms-P937 (nms1286937)IC5010000.0 [1]
3-[4-(Morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrileIC50178.0 [1]
5-[2,4-Dihydroxy-6-(4-Nitrophenoxy)phenyl]-N-(1-Methylpiperidin-4-Yl)-1,2-Oxazole-3-CarboxamideIC5010.0 [1]
5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamideIC5010000.0 [1]
2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamideIC5010000.0 [1]
(7S)-2-(2-Aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-oneIC504000.0 [1]
Khk-IN-1IC5040000.0 [1]
8-[(5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneIC5020.0 [1]
3-[(4-Morpholin-4-ylbenzoyl)amino]-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]-1H-thieno[3,2-c]pyrazole-5-carboxamideIC50412.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-oneIC502220.0 [1]
CID 71553154IC503840.0 [1]
TilfrinibIC5010000.0 [1]
3-[[5-(1,3-Benzodioxol-5-yl)-[1,2,4]triazolo[1,5-c]quinazolin-8-yl]amino]propan-1-olIC5010000.0 [1]
3-[4-[(2S)-2-(5-Methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrileIC5012095.0 [1]
3-[4-(2,3,3a,4,6,6a-Hexahydrofuro[2,3-c]pyrrol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrileIC5010218.0 [1]
4-[4-[3-[4-[(Propan-2-ylamino)methyl]anilino]-1H-pyrazol-5-yl]phenyl]benzene-1,3-diolIC501850.0 [1]
5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamideIC5010.0 [1]
5-[2,4-Dihydroxy-6-[4-(propan-2-ylamino)phenoxy]phenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamideIC5010.0 [1]
5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-[1-(1,4-dioxaspiro[4.5]decan-8-yl)piperidin-4-yl]-1,2-oxazole-3-carboxamideIC5010.0 [1]
3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin-7-ylcarbamoyl)-benzyl]-benzamideIC5010000.0 [1]
1-Methyl-2-[2-[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)anilino]pyrimidin-4-yl]-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-4-oneIC5010000.0 [1]
8-[(1-Acetylpiperidin-4-yl)amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamideIC5010000.0 [1]
8-[(1-Benzoylpiperidin-4-yl)amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamideIC5010000.0 [1]
N,1-Dimethyl-8-[[1-(1-methylsulfonylpiperidine-4-carbonyl)piperidin-4-yl]amino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamideIC5010000.0 [1]
2-{[2-Amino-5-(1,3-Benzodioxol-5-Ylmethyl)[1,2,4]triazolo[1,5-C]quinazolin-8-Yl]amino}ethanolIC5010000.0 [1]
5-(1,3-Benzodioxol-5-ylmethyl)-[1,2,4]triazolo[1,5-c]quinazoline-2,8-diamineIC5010000.0 [1]
5-(1,3-Benzodioxol-5-Ylmethyl)-10-Fluoro[1,2,4]triazolo[1,5-C]quinazolin-2-AmineIC5010000.0 [1]
5-(1,3-Benzodioxol-5-ylmethyl)-10-fluoro-8-(4-methylpiperazin-1-yl)-[1,2,4]triazolo[1,5-c]quinazolin-2-amineIC5010000.0 [1]
1-Methyl-5-[2-[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)anilino]pyrimidin-4-yl]pyrrole-3-carboxamideIC5010000.0 [1]
8-N-(Cyclopropylmethyl)-4-N-(2-methylsulfanylphenyl)-2-(4-piperidin-4-ylpiperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamineIC5010000.0 [1]
2-[(4S)-7-(3-Chlorophenyl)-1-oxo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methylpiperazin-1-yl)ethyl]acetamideIC5010000.0 [1]
2-(3,5-Dichloroanilino)-4-[[4-(dimethylamino)cyclohexyl]amino]-N-(1-methylpiperidin-4-yl)pyrimidine-5-carboxamideIC5030000.0 [1]
2-(3,5-Dichloroanilino)-4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-N-(1-methylpiperidin-4-yl)pyrimidine-5-carboxamideIC5030000.0 [1]
3-{4-[(2S)-2-Methylmorpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrileIC501099.0 [1]
3-[4-[2-(3-Methyl-1,2,4-oxadiazol-5-yl)morpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrileIC5032000.0 [1]
4-[5-(3-Cyanophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine-2-carbonitrileIC506208.0 [1]
N-(2,2-Dimethylpropyl)-2-(1-oxo-7-thiophen-3-yl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-4-yl)acetamideIC5010000.0 [1]
3-[4-[(2R)-2-(5-Methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrileIC509430.0 [1]
Items per page: 1 - 10 of 40
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References

This online tool may be cited as follows

MLA

"Quest Database™ Serine/threonine-protein kinase MST4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-mst4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Serine/threonine-protein kinase MST4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-mst4-inhibitors-ic50-ki.
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