Serine/threonine-protein kinase D2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Doramapimod	IC50	30000.0 [1]
	7-Hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one	IC50	280.0 [1]
	JNK Inhibitor VIII	Ki	5300.0 [1]
	CID 53246941	IC50	139.0 [1]
	CID 59604787	IC50	10000.0 [1]
	Bpkdi	IC50	9.0 [1]
	N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)acetamide	Ki	2500.0 [1]
	4-Amino-5-chloro-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide	Ki	5200.0 [1]
	7-Chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrile	Ki	8980.0 [1]
	1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acid	IC50	10000.0 [1]
	7-Chloro-8-(3-hydroxypropoxy)-3-oxo-11,17-dioxa-2,4,20,22-tetrazatricyclo[16.3.1.05,10]docosa-1(21),5,7,9,18(22),19-hexaene-19-carbonitrile	Ki	10000.0 [1]
	7-Chloro-8-(3-hydroxypropyl)-3-oxo-11,17-dioxa-2,4,20,22-tetrazatricyclo[16.3.1.05,10]docosa-1(21),5(10),6,8,18(22),19-hexaene-19-carbonitrile	Ki	10000.0 [1]
	N-(7-Chloro-19-cyano-3-oxo-11,17-dioxa-2,4,20,22-tetrazatricyclo[16.3.1.05,10]docosa-1(21),5,7,9,18(22),19-hexaen-8-yl)methanesulfonamide	Ki	10000.0 [1]
	N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxy-4-methylsulfonylphenyl)acetamide	Ki	9000.0 [1]
	N-(4-Amino-5-chloro-6-ethoxypyridin-2-yl)-2-(4-methanesulfonyl-2,5-dimethoxyphenyl)acetamide	Ki	9000.0 [1]
	N-(4-Amino-5-cyano-6-isopropoxypyridin-2-yl)-2-(4-methanesulfonyl-2,5-dimethoxyphenyl)acetamide	Ki	950.0 [1]
	N-(4-Amino-5-cyano-6-phenylpyridin-2-yl)acetamide	Ki	9000.0 [1]
	(13R,15S)-13-Methyl-16-oxa-8,9,12,22,24-pentazahexacyclo[15.6.2.16,9.112,15.02,7.021,25]heptacosa-1(24),2,4,6,17,19,21(25)-heptaene-23,27-dione	IC50	1000.0 [1]
	5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide	IC50	10000.0 [1]
	5-(2-Aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine	IC50	950.0 [1]
	N-[3-[5-[2-(3-Morpholin-4-ylanilino)pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-phenylacetamide	IC50	1000.0 [1]
	1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)urea	IC50	30000.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	2-[3-(3-Piperidin-4-ylpropoxy)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide	Ki	2000.0 [1]
	2-[3-(Methanesulfonamido)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide	Ki	1000.0 [1]
	6-[4-[(5-Tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-N-[3-(dimethylamino)propyl]imidazo[2,1-b][1,3]thiazole-3-carboxamide	IC50	10000.0 [1]
	4-(2-Chloro-4-fluorophenyl)-8-(2,6-dichlorophenyl)-7-oxido-1,7-naphthyridin-7-ium	IC50	10000.0 [1]
	N-Cyclohexyl-4-[6-piperazin-1-yl-4-(1H-pyrazol-5-yl)pyridin-2-yl]pyridin-2-amine	IC50	62.0 [1]
	4-[6-Piperazin-1-yl-4-(1H-pyrazol-4-yl)pyridin-2-yl]-N-propan-2-ylpyridin-2-amine	IC50	2.0 [1]
	N-(Oxan-4-yl)-4-[6-piperazin-1-yl-4-(1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-amine	IC50	2.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-[[(3R)-pyrrolidin-3-yl]amino]pyridine-4-carboxamide	IC50	18.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-[[(3S)-pyrrolidin-3-yl]amino]pyridine-4-carboxamide	IC50	540.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-[(3R)-3-methylpiperazin-1-yl]pyridine-4-carboxamide	IC50	60.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-[(3S)-3-methylpiperazin-1-yl]pyridine-4-carboxamide	IC50	86.0 [1]
	2-(3-Aminopiperidin-1-yl)-6-[2-(cyclohexylamino)pyridin-4-yl]pyridine-4-carboxamide	IC50	168.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-(4-methylpiperazin-1-yl)pyridine-4-carboxamide	IC50	238.0 [1]
	2-[4-(Aminomethyl)piperidin-1-yl]-6-[2-(cyclohexylamino)pyridin-4-yl]pyridine-4-carboxamide	IC50	212.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-(3,3-dimethylpiperazin-1-yl)pyridine-4-carboxamide	IC50	427.0 [1]
	N-Cyclohexyl-4-[6-piperazin-1-yl-4-(trifluoromethyl)pyridin-2-yl]pyridin-2-amine	IC50	101.0 [1]
	N-Cyclohexyl-4-[4-(difluoromethyl)-6-piperazin-1-ylpyridin-2-yl]pyridin-2-amine	IC50	76.0 [1]
	2-(2-Anilinopyridin-4-yl)-6-piperazin-1-ylpyridine-4-carboxamide	IC50	1.0 [1]
	2-[2-(Oxan-4-ylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide	IC50	9.0 [1]
	2-Piperazin-1-yl-6-[2-(propan-2-ylamino)pyridin-4-yl]pyridine-4-carboxamide	IC50	8.0 [1]
	2-[2-[(1-Methylpyrazol-3-yl)amino]pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide	IC50	7.0 [1]
	2-[2-(2-Chloroanilino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide	IC50	8.0 [1]
	2-[2-(Cyclopentylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide	IC50	59.0 [1]
	2-[2-(Ethylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide	IC50	31.0 [1]
	2-[2-(Cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carbonitrile	IC50	130.0 [1]
	2-(2-Anilinopyridin-4-yl)-6-piperazin-1-ylpyridine-4-carbonitrile	IC50	35.0 [1]
	2-[2-[(1-Methylpyrazol-3-yl)amino]pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carbonitrile	IC50	68.0 [1]
	N-Cyclohexyl-4-[6-piperazin-1-yl-4-(1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-amine	IC50	1.0 [1]
	N-[(1R)-1-Cyanoethyl]-3-[5-[4-[(oxan-4-ylamino)methyl]phenyl]-1,2-oxazol-3-yl]benzamide	IC50	48.0 [1]
	4-Methoxy-8,14-dithia-3,5,11-triazatricyclo[7.5.0.02,7]tetradeca-1(9),2,4,6-tetraen-10-one	IC50	50.0 [1]
	4-[2-Amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(Z,2R)-5,5,5-trifluoropent-3-en-2-yl]oxybenzamide	IC50	330.0 [1]
	2-[3-(3-Piperazin-1-ylpropoxy)phenyl]-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide	IC50	1000.0 [1]
	6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	IC50	46000.0 [1]
	6-(2,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	IC50	1300.0 [1]
	3-(Tert-butylamino)-4-[[2-(4-pyridin-4-ylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione	Ki	175.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 58 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase D2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-d2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 21). Quest Database™ Serine/threonine-protein kinase D2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-d2-inhibitors-ic50-ki.
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