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Sentrin-specific protease 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3-Phenyl-N-[[3-[[(E)-3-phenylprop-2-enoyl]amino]phenyl]methyl]benzamideIC503300.0 [1], 9200.0 [2]
5-Chloro-N'-(cyclohexylmethylene)-2-hydroxybenzohydrazideIC5014000.0 [1]
Spongiacidin CIC5031600.0 [1]
2-[(5-Phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]-N-(4-sulfamoylphenyl)acetamideIC5020800.0 [1]
2-(4-Chlorophenyl)-2-oxoethyl 4-(benzoylamino)benzoateIC503542.0 [1]
CID 71451488IC501080.0 [1]
5-(2,5-Dichlorophenyl)-N-{3-[(phenylcarbonyl)amino]phenyl}furan-2-carboxamideIC5017600.0 [1]
1-(2-Hydroxy-4-methoxyphenyl)-2-({5-nitro-1H-benzimidazol-2-yl}sulfanyl)ethanoneIC5021200.0 [1]
2-[(3-Methylbenzyl)sulfanyl]-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamideIC5023500.0 [1]
N-(3-{5-[(2-Anilino-2-oxoethyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}phenyl)-4-methylbenzamideIC5015800.0 [1]
Benzyl N-[1-(2-hydroxyethyl)-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamateIC50100000.0 [1]
2-(4-Chlorophenyl)-2-oxoethyl 4-[(3-methoxybenzoyl)amino]benzoateIC502385.0 [1]
3-(3-Bromophenyl)-N-[[3-[[(E)-3-phenylprop-2-enoyl]amino]phenyl]methyl]benzamideIC5016400.0 [1]
3-Phenylmethoxy-N-[[3-(3-phenylpropanoylamino)phenyl]methyl]benzamideIC508000.0 [1]
N-[(3-Benzamidophenyl)methyl]-3-(4-bromophenyl)benzamideIC509100.0 [1]
3-(4-Bromophenyl)-N-[[3-(3-phenylpropanoylamino)phenyl]methyl]benzamideIC5015300.0 [1]
3-Phenylmethoxy-N-[[3-[[(E)-3-phenylprop-2-enoyl]amino]phenyl]methyl]benzamideIC506200.0 [1]
3-Phenyl-N-[[3-(3-phenylpropanoylamino)phenyl]methyl]benzamideIC508500.0 [1]
3-(4-Methoxyphenyl)-N-[[3-[[(E)-3-phenylprop-2-enoyl]amino]phenyl]methyl]benzamideIC504900.0 [1]
N-[[3-[[(E)-3-Phenylprop-2-enoyl]amino]phenyl]methyl]naphthalene-1-carboxamideIC5012400.0 [1]
3-(4-Bromophenyl)-N-[[3-[[(E)-3-phenylprop-2-enoyl]amino]phenyl]methyl]benzamideIC506400.0 [1]
N-[(3-Benzamidophenyl)methyl]-1-benzothiophene-2-carboxamideIC5026600.0 [1]
N-[[3-[[(E)-3-Phenylprop-2-enoyl]amino]phenyl]methyl]-1-benzothiophene-2-carboxamideIC507100.0 [1]
N-[[3-[[(E)-3-Phenylprop-2-enoyl]amino]phenyl]methyl]naphthalene-2-carboxamideIC507600.0 [1]
3-(4-Methoxyphenyl)-N-[[3-(3-phenylpropanoylamino)phenyl]methyl]benzamideIC503500.0 [1]
(E)-2-Cyano-3-(2-hydroxyphenyl)-N-[(E)-(2-hydroxyphenyl)methylideneamino]prop-2-enamideIC5020700.0 [1]
(E)-5-(2-Hydroxybenzylidene)-2-(4-phenylpiperazin-1-yl)thiazol-4(5H)-oneIC5028400.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3-nitrobenzoyl)amino]benzoateIC501856.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3,4-dimethoxybenzoyl)amino]benzoateIC5050000.0 [1]
3-Chloro-N-[[3-[[(3-chloro-6-fluoro-1-benzothiophene-2-carbonyl)amino]methyl]phenyl]methyl]-6-fluoro-1-benzothiophene-2-carboxamideIC5015000.0 [1]
1-(4-Chlorophenyl)-2-oxo-2-phenylethyl ({[(4-bromobenzoyl)amino]acetyl}amino)acetateIC5047900.0 [1]
Benzyl N-[3-[[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoyl]phenyl]carbamateIC509200.0 [1]
(E)-3-Naphthalen-2-yl-N-[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]prop-2-enamideIC5021800.0 [1]
Tert-butyl N-[3-[[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoyl]phenyl]carbamateIC50100000.0 [1]
N-[2-Oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]naphthalene-2-sulfonamideIC5021200.0 [1]
Benzyl N-[2-oxo-1-(3-oxopropyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamateIC50100000.0 [1]
3-Acetamido-N-[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]benzamideIC50100000.0 [1]
Tert-butyl N-[4-[[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoyl]phenyl]carbamateIC50100000.0 [1]
Benzyl N-[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamateIC5027200.0 [1]
Benzyl N-[2-oxo-1-(2-oxoethyl)-3H-1,4-benzodiazepin-3-yl]carbamateIC50100000.0 [1]
Benzyl N-[4-[[2-oxo-1-(2-oxoethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoyl]phenyl]carbamateIC5015500.0 [1]
3-Nitro-N-(3-{[(2E)-2-(3-nitrobenzylidene)hydrazinyl]carbonyl}phenyl)benzamideIC5018400.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3-hydroxybenzoyl)amino]benzoateIC5050000.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3-bromobenzoyl)amino]benzoateIC501175.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3-fluorobenzoyl)amino]benzoateIC501735.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3-aminobenzoyl)amino]benzoateIC5050000.0 [1]
[2-(4-Chlorophenyl)-2-oxoethyl] 4-[(3,4-diethoxybenzoyl)amino]benzoateIC5050000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Sentrin-specific protease 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/sentrin-specific-protease-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Sentrin-specific protease 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sentrin-specific-protease-1-inhibitors-ic50-ki.
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