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Salivary alpha-amylase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
PentagalloylglucoseIC502350.0 [1]
PentagalloylglucoseKi2600.0 [1]
(-)-Epigallocatechin gallateIC501400000.0 [1]
PrecoseIC50500.0 [1]
4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenolIC501043000.0 [1]
4-[4-(2,4-Dihydroxy-phenyl)-thiazol-2-ylamino]-benzenesulfonamideIC50165000.0 [1]
4-{2-[(4-Hydroxyphenyl)amino]-1,3-thiazol-4-yl}phenolIC50492000.0 [1]
1-(3-Methoxyphenyl)-3-{6-oxo-4-[(pyridin-2-ylsulfanyl)methyl]-1,6-dihydropyrimidin-2-yl}guanidineIC50330000.0 [1]
4-(1,3-Benzodioxol-5-YL)-5-(5-ethyl-2,4-dihydroxyphenyl)-2H-pyrazole-3-carboxylic acidIC504000000.0 [1]
4-(4-Phenyl-thiazol-2-ylamino)-phenolIC501274000.0 [1]
Phenol, 2,6-bis[(2-hydroxy-5-methylphenyl)methyl]-4-methyl-IC50200000.0 [1]
3-[[(5E)-5-[(5-Bromo-2-hydroxy-3-methoxyphenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acidIC50260000.0 [1]
4-[[4-(4-Methylphenyl)-1,3-thiazol-2-yl]amino]phenolIC50735000.0 [1]
4-(2-(4-Hydroxyphenylamino)thiazol-4-yl)benzene-1,3-diolIC50138000.0 [1]
4-{[3-(2,4-Dihydroxyphenyl)-5-methyl-1H-pyrazol-4-yl]oxy}benzoic acidIC504000000.0 [1]
5-{[4-(2,4-Dihydroxyphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acidIC50423000.0 [1]
(5Z)-5-[(5-Chloro-2-hydroxyphenyl)methylidene]-3-[(3-nitrophenyl)methyl]-1,3-thiazolidine-2,4-dioneIC5050000.0 [1]
3-[(5Z)-5-[(2-Hydroxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acidIC5062000.0 [1]
4-{[4-(2,4-Dihydroxyphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acidIC50642000.0 [1]
4-{[4-(2,4-Dihydroxyphenyl)-1,3-thiazol-2-yl]amino}benzoic acidIC50680000.0 [1]
1-(3-{[4-(2,4-Dihydroxyphenyl)-1,3-thiazol-2-yl]amino}phenyl)ethanoneIC50100000.0 [1]
(7R,8S,9S,10R)-7-[[(2S,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-8,9,10-trihydroxy-2-sulfanylidene-6-oxa-1,3-diazaspiro[4.5]decan-4-oneKi190.0 [1]
N'-[(E)-1-(2,4-Dihydroxyphenyl)ethylideneamino]-N-(2-methylphenyl)butanediamideIC50850000.0 [1]
(5E)-2-(4-Acetylpiperazin-1-yl)-5-(2-hydroxybenzylidene)-1,3-thiazol-4(5H)-oneIC50700000.0 [1]
2-[6-(2-Hydroxy-3-methoxyphenyl)-4,4-dimethyl-3,5-dinitropiperidin-2-yl]-6-methoxyphenolIC50300000.0 [1]
1-{[2-({[5-(2-Fluorophenyl)-2-furyl]methyl}amino)ethyl]amino}-2-propanolIC501000000.0 [1]
4-[2-(4-Dimethylamino-phenylamino)-thiazol-4-yl]-benzene-1,3-diolIC50100000.0 [1]
5-[5-[[4-[5-[3,4-Dihydroxy-6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]-3,4-dihydroxy-6-methyloxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triolKi700.0 [1]
4-N-[4-(2,4-Dichlorophenyl)-1,3-thiazol-2-yl]benzene-1,4-diamineIC50270000.0 [1]
2-{2-[(4-Methoxyphenyl)amino]-1,3-thiazol-4-yl}phenolIC5040000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Salivary alpha-amylase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/salivary-alpha-amylase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Salivary alpha-amylase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/salivary-alpha-amylase-inhibitors-ic50-ki.
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