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RNase L Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
5'-O-Monophosphoryladenylyl(2'->5')adenylyl(2'->5')adenosineIC501.1 [1], 7.3 [2], 13.0 [3], 20.0 [4]
[4-(6-Aminopurin-9-yl)-3-[[4-(6-aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methoxy-hydroxyphosphoryl]oxy-2-hydroxycyclopentyl]methyl [5-(6-aminopurin-9-yl)-2-hydroxy-3-(phosphonooxymethyl)cyclopentyl] hydrogen phosphateIC50210.0 [1], 2300.0 [2]
[[(2R,3R,4R,5R)-4-[[(2R,3R,4R,5R)-4-[[(2R,3S,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC500.72 [1]
[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-2-(6-amino-2-methylpurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphateIC501060.0 [1]
[[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC5024.0 [1]
[[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC50105.0 [1]
[(2R,3R,4R,5R)-2-(6-Amino-2-methylpurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl hydrogen phosphateIC5057.0 [1]
[(2R,3R,4R,5R)-4-[[(2R,3S,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphateIC502.6 [1]
[(2R,3S,4R,5S)-5-(6-Aminopurin-9-yl)-3-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxyoxolan-2-yl]methyl [(2R,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-hydroxy-2-phosphonooxyoxolan-3-yl] hydrogen phosphateIC5050000.0 [1]
[(2R,3R,4R,5R)-5-(6-Aminopurin-9-yl)-4-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-phosphonooxyoxolan-3-yl] hydrogen phosphateIC501000.0 [1]
[(2R,3R,4R,5S)-5-(6-Aminopurin-9-yl)-4-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-phosphonooxyoxolan-3-yl] hydrogen phosphateIC5050000.0 [1]
Items per page: 1 - 10 of 11
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References

This online tool may be cited as follows

MLA

"Quest Database™ RNase L Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/rnase-l-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ RNase L Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/rnase-l-inhibitors-ic50-ki.
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