 | Fasudil | IC50 | 300.0 [1] |
 | Fasudil | Ki | 100.0 [1], 530.0 [2] |
 | Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans- | IC50 | 93.0 [1], 150.0 [2], 870.96 [3] |
 | Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans- | Ki | 25.12 [1], 150.0 [2], 220.0 [3] |
 | Hydroxyfasudil | IC50 | 758.58 [1] |
 | Hydroxyfasudil | Ki | 31.62 [1], 150.0 [2] |
 | Staurosporine | IC50 | 0.64 [1], 0.68 [2], 1.1 [3], 19.0 [4] |
 | (S)-6-(Piperidin-3-yloxy)-isoquinolin-1-ylamine | IC50 | 2137.96 [1], 5011.87 [2] |
 | (S)-6-(Piperidin-3-yloxy)-isoquinolin-1-ylamine | Ki | 37.15 [1] |
 | (S)-6-(Piperidin-3-yloxy)-2H-isoquinolin-1-one | IC50 | 61.66 [1], 251.19 [2], 660.69 [3] |
 | (S)-6-(Piperidin-3-yloxy)-2H-isoquinolin-1-one | Ki | 2.51 [1] |
 | 5-(1,4-Diazepan-1-ylsulfonyl)isoquinolin-1-amine | IC50 | 758.58 [1], 3162.28 [2], 6918.31 [3] |
 | 5-(1,4-Diazepan-1-ylsulfonyl)isoquinolin-1-amine | Ki | 34.67 [1] |
 | (S)-2-Methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | IC50 | 5.0 [1] |
 | (S)-2-Methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | Ki | 6.0 [1] |
 | 4-(4-Fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide | IC50 | 14.0 [1], 100.0 [2] |
 | 4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine | IC50 | 10.0 [1], 13.0 [2], 19.0 [3] |
 | (S)-6-(1-Benzylpiperidine-3-yloxy)isoquinolin-1-yl amine | IC50 | 239.88 [1], 776.25 [2] |
 | Y-27632 Dihydrochloride | IC50 | 46.0 [1] |
 | Y-27632 Dihydrochloride | Ki | 140.0 [1] |
 | Benzamide, 4-(1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, (R)- | IC50 | 30.0 [1], 120.0 [2] |
 | Aminofurazanyl-azabenzimidazole 6n | IC50 | 1.6 [1], 1.8 [2] |
 | 5-Aminoindazole | IC50 | 181300.0 [1] |
 | 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea | IC50 | 8.0 [1], 9.0 [2] |
 | 1-[(1S)-2-Hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea | IC50 | 1690.0 [1] |
 | N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-YL)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide | IC50 | 56.0 [1] |
 | [3-[[4-(Aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carbonyl]amino]phenyl] N,N-dimethylcarbamate | IC50 | 69.0 [1], 2200.0 [2] |
 | 5-Bromo-N-(pyridin-4-yl)pyridine-3-carboxamide | IC50 | 270000.0 [1] |
 | [2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone | IC50 | 5.6 [1], 14.0 [2] |
 | 1-Benzyl-3-(1H-indazol-5-yl)urea | IC50 | 13900.0 [1] |
 | Nicotinamide, N-(4-pyridyl)- | IC50 | 75500.0 [1] |
 | (2s)-1-{[6-Furan-3-Yl-5-(3-Methyl-2h-Indazol-5-Yl)pyridin-3-Yl]oxy}-3-(1h-Indol-3-Yl)propan-2-Amine | IC50 | 1580.0 [1] |
 | 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea | IC50 | 23.0 [1], 27.0 [2] |
 | CID 24832012 | Ki | 165.0 [1], 170.0 [2] |
 | 4-[1-Ethyl-7-(piperidin-4-yloxy)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine | IC50 | 8.0 [1] |
 | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3R)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | IC50 | 890.0 [1], 1580.0 [2] |
 | 2-(4-(6-(Pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-yl)piperazin-1-yl)ethanol | IC50 | 300.0 [1], 570.0 [2] |
 | 2-(3-Methoxyphenyl)-N-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]acetamide | Ki | 83.0 [1], 100.0 [2] |
 | N-[(3-Methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)-1H-indole-2-carboxamide | IC50 | 19.0 [1] |
 | N-[(3-Methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide | IC50 | 1.0 [1] |
 | N-[(3-Methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | IC50 | 12.0 [1] |
 | N-[(3-Methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide | IC50 | 11.0 [1] |
 | 1-(1H-Indazol-5-yl)-3-phenylurea | IC50 | 157100.0 [1] |
 | 4-N-(2,3-Dihydro-1H-inden-2-yl)-2-piperazin-1-yl-6-N-pyridin-4-ylpyrimidine-4,6-diamine | IC50 | 2.0 [1], 12.0 [2] |
 | 4-N-(2,3-Dihydro-1H-inden-2-yl)-6-piperazin-1-yl-2-N-pyridin-4-ylpyrimidine-2,4-diamine | IC50 | 14.0 [1], 154.0 [2] |
 | 4-(2,3-Dihydro-1H-inden-2-yloxy)-6-piperazin-1-yl-N-pyridin-4-yl-1,3,5-triazin-2-amine | IC50 | 8.0 [1], 57.0 [2] |
 | 6-(1,4-Diazepan-1-yl)-2-N-(2,3-dihydro-1H-inden-2-yl)-4-N-pyridin-4-yl-1,3,5-triazine-2,4-diamine | IC50 | 11.0 [1], 17.0 [2] |
 | 2-N-(2,3-Dihydro-1H-inden-2-yl)-6-piperazin-1-yl-4-N-pyridin-4-yl-1,3,5-triazine-2,4-diamine | IC50 | 6.0 [1], 30.0 [2] |
 | 2-N-(2,3-Dihydro-1H-inden-2-yl)-6-[(3R)-3-methylpiperazin-1-yl]-4-N-pyridin-4-yl-1,3,5-triazine-2,4-diamine | IC50 | 8.0 [1], 26.0 [2] |
 | 1-Phenethyl-3-[4-(4-pyridyl)thiazol-2-yl]urea | IC50 | 480.0 [1] |
 | 6-[(3S)-1-Benzylpiperidin-3-yl]oxyisoquinoline | IC50 | 169.82 [1], 331.13 [2] |
 | 6-[(2-Phenylethylamino)methyl]isoquinolin-1-amine | IC50 | 1288.25 [1] |
 | 6-[(2-Phenylethylamino)methyl]isoquinolin-1-amine | Ki | 63.1 [1] |
 | 1-Benzyl-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 170.0 [1] |
 | 1-(1h-Indazol-5-Yl)-3-(2-Phenylethyl)urea | IC50 | 650.0 [1] |
 | 1-[(1r)-1-(3-Methoxyphenyl)ethyl]-3-(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)urea | IC50 | 30.0 [1] |
 | 1-[(1R)-2-Hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea | IC50 | 9070.0 [1] |
 | 1-[(2R)-1-Hydroxy-3-phenylpropan-2-yl]-3-(4-pyridin-4-ylphenyl)urea | IC50 | 1410.0 [1] |
 | 1-Benzyl-3-[4-(4-pyridinyl)phenyl]urea | IC50 | 1150.0 [1] |
 | 2-{3-[3-(Piperidin-4-Yl)propoxy]phenyl}-N-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]acetamide | IC50 | 7.0 [1] |
 | 2-{3-[3-(Piperidin-4-Yl)propoxy]phenyl}-N-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]acetamide | Ki | 13.0 [1] |
 | 2-[3-(3-Piperazin-1-ylpropoxy)phenyl]-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide | IC50 | 8.0 [1] |
 | 2-[3-(3-Piperazin-1-ylpropoxy)phenyl]-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide | Ki | 51.0 [1] |
 | 1'-(4-Fluorophenyl)-1'-hydroxy-6-(5-methyl-1H-pyrazol-4-yl)spiro[1,3-dihydrothieno[3,2-d]pyrimidine-2,4'-cyclohexane]-4-one | IC50 | 130.0 [1], 820.0 [2] |
 | 1'-Cyclohexyl-1'-hydroxy-6-(5-methyl-1H-pyrazol-4-yl)spiro[1,3-dihydrothieno[3,2-d]pyrimidine-2,4'-cyclohexane]-4-one | IC50 | 350.0 [1], 2900.0 [2] |
 | 3-[(3-Methoxyphenyl)methyl]-1-methyl-1-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 30.0 [1], 60.0 [2] |
 | 1-[(2S)-1-Hydroxy-3-phenylpropan-2-yl]-3-(4-pyridin-4-ylphenyl)urea | IC50 | 31010.0 [1] |
 | 3-(1H-Indazol-5-yl)-1,1-dimethylurea | IC50 | 59100.0 [1] |
 | 1-(2-Phenylethyl)-3-(4-pyridin-4-ylphenyl)urea | IC50 | 2610.0 [1] |
 | 5-(4-Fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide | IC50 | 400000.0 [1], 4000000.0 [2] |
 | 1-(2-Hydroxy-2-phenylethyl)-3-(1H-indazol-5-yl)urea | IC50 | 2900.0 [1] |
 | 1-(1H-Indazol-5-yl)-3-(3-phenylpropyl)urea | IC50 | 2460.0 [1] |
 | 4-Chloro-N-pyridin-4-ylpyridine-3-carboxamide | IC50 | 72500.0 [1] |
 | 4-(4-Fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide | IC50 | 400000.0 [1], 4000000.0 [2] |
 | 1-(1H-Indazol-5-yl)-3-[2-(4-methoxyphenyl)ethyl]urea | IC50 | 2600.0 [1] |
 | 1-[2-(4-Chlorophenyl)ethyl]-3-(1H-indazol-5-yl)urea | IC50 | 2200.0 [1] |
 | 3-(1H-Indazol-5-yl)-1-methyl-1-(2-phenylethyl)urea | IC50 | 21500.0 [1] |
 | 1-[(4-Methylphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 5160.0 [1], 5200.0 [2] |
 | 1-[1-(3-Fluorophenyl)ethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 430.0 [1] |
 | 1-[(3-Chlorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 140.0 [1] |
 | 1-[(3-Ethoxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 2100.0 [1], 2140.0 [2] |
 | 1-[(1R)-2-Hydroxy-1-phenylethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 5200.0 [1] |
 | 1-[(2-Fluorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 400.0 [1] |
 | 1-[(3-Aminophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 50.0 [1] |
 | 1-[(2-Methylphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 150.0 [1] |
 | 1-[(1S)-1-Phenylethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 2900.0 [1], 3290.0 [2] |
 | 1-(2-Hydroxy-1-phenylethyl)-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 60.0 [1] |
 | 1-[(4-Chlorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 2390.0 [1], 2400.0 [2] |
 | 1-Benzyl-1-methyl-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 110.0 [1] |
 | 1-[(4-Fluorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 570.0 [1] |
 | 1-[(3-Propoxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 3360.0 [1] |
 | 1-[[3-(2-Methoxyethoxy)phenyl]methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 500.0 [1] |
 | 1-[(1S)-1-Phenylpropyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 52170.0 [1], 52200.0 [2] |
 | 1-[(2-Chlorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 340.0 [1] |
 | 1-[(4-Hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 380.0 [1] |
 | 1-[(3-Methoxyphenyl)methyl]-1-methyl-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 40.0 [1] |
 | 1-[(2-Hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 620.0 [1] |
 | 1-[(1R)-2-Methoxy-1-phenylethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 29480.0 [1], 29500.0 [2] |
 | 1-[(3-Fluorophenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | IC50 | 100.0 [1] |
 | (2S)-2-Phenyl-2-[(4-pyridin-4-yl-1,3-thiazol-2-yl)carbamoylamino]acetamide | IC50 | 80.0 [1] |