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Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
Oleanolic acidIC5011800.0 [1], 22310.0 [2], 40000.0 [3], 120000.0 [4]
4-Bromo-3-(carboxymethoxy)-5-[4-[[oxo(3-pyridinyl)methyl]amino]phenyl]-2-thiophenecarboxylic acidIC50320000.0 [1]
4-Bromo-3-(carboxymethoxy)-5-[4-[[oxo(3-pyridinyl)methyl]amino]phenyl]-2-thiophenecarboxylic acidKi320000.0 [1]
4-Bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acidKi500000.0 [1], 1000000.0 [2]
Ursolic acidIC503800.0 [1], 40000.0 [2]
2-(Oxalyl-amino)-benzoic acidKi2000000.0 [1]
5-Iodo-2-(oxaloamino)benzoic acidKi420000.0 [1]
6-(Oxalyl-amino)-1H-indole-5-carboxylic acidKi450000.0 [1], 550000.0 [2]
2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-C]pyran-3-carboxylic acidKi360000.0 [1]
2-(Carboxyformamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acidKi410000.0 [1]
1H-Indole-7-carboxylic acid, 6-[(carboxycarbonyl)amino]-Ki450000.0 [1], 550000.0 [2]
2-(Carboxyformamido)thiophene-3-carboxylic acidKi2000000.0 [1]
3-(Carboxyformamido)thiophene-2-carboxylic acidKi2000000.0 [1]
2-[4-[[3,5-Bis[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC5041000.0 [1]
4-Bromo-5-[4-[(2-carboxyacetyl)amino]phenyl]-3-(carboxymethoxy)thiophene-2-carboxylic acidKi1000000.0 [1]
4-Bromo-3-(carboxymethoxy)-5-[3-[(3,3,5,5-tetramethylcyclohexyl)amino]phenyl]thiophene-2-carboxylic acidKi1000000.0 [1]
4-[5-(4-Benzyloxybenzylidene)-2,4-dioxothiazolidin-3-yl]methylbenzoic acidIC5027000.0 [1]
4-Bromo-3-(carboxymethoxy)-5-[4-(dimethylamino)phenyl]thiophene-2-carboxylic acidKi1000000.0 [1]
Azane;[4-[4-ethoxy-2,2-bis(methoxycarbonyl)-4-oxobutyl]phenyl]sulfamic acidIC50288000.0 [1], 500000.0 [2]
Azane;[4-[2,2-bis(methoxycarbonyl)-5-phenylpentyl]phenyl]sulfamic acidIC50409000.0 [1], 500000.0 [2]
Azane;[4-[2-ethoxycarbonyl-3-methoxy-3-oxo-2-(phenylmethoxycarbonylamino)propyl]phenyl]sulfamic acidIC50227000.0 [1], 472000.0 [2]
Maslinic acidIC5040000.0 [1]
CryptotanshinoneIC5036900.0 [1]
Corosolic acidIC5040000.0 [1]
Moronic acidIC5045600.0 [1]
4-Hydroxyphenylglyoxylic acidIC502300000.0 [1]
Morolic acidIC5035900.0 [1]
2-(Oxalyl-amino)-4,5,6,7-tetrahydro-thieno[2,3-C]pyridine-3-carboxylic acidKi2000000.0 [1]
(4As,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(3-carboxy-3-methylbutanoyl)oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acidIC5040000.0 [1]
3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diolIC5050000.0 [1]
Cefsulodin sodium saltIC50200000.0 [1]
6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acidIC5050000.0 [1]
Illudalic acidIC501300.0 [1]
1-Oxobenzo[f]chromene-2-carbaldehydeIC501000000.0 [1]
4-[4-(2,4-Dihydroxy-6-propylbenzoyl)oxy-2-hydroxy-6-propylbenzoyl]oxy-2-hydroxy-6-propylbenzoic acidIC5020000.0 [1]
2-[4-[[4-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC50250000.0 [1]
Benzoic acid, 2-[(carboxycarbonyl)amino]-3-methyl-Ki2000000.0 [1]
2-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxo-2-(prop-2-enoxycarbonylamino)propyl]-N-oxaloanilino]benzoic acidKi96000.0 [1]
3-(Carboxyformamido)-5-(thiophen-3-yl)thiophene-2-carboxylic acidKi90000.0 [1]
3-(Carboxyformamido)-5-phenylthiophene-2-carboxylic acidKi90000.0 [1]
2-(Carboxyformamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acidKi400000.0 [1]
3-(Carboxyformamido)isonicotinic acidKi2000000.0 [1]
Benzoic acid, 2-[(carboxycarbonyl)methylamino]-Ki2000000.0 [1]
3-(Carboxyformamido)-5-(4-(carboxymethoxy)phenyl)thiophene-2-carboxylic acidKi50000.0 [1]
Benzoic acid, 2-[(carboxycarbonyl)amino]-6-methyl-Ki2000000.0 [1]
3-(Carboxyformamido)-4-methylthiophene-2-carboxylic acidKi2000000.0 [1]
5-[3-[(1-Benzylsulfonylpiperidin-4-yl)amino]phenyl]-4-bromo-3-(carboxymethoxy)thiophene-2-carboxylic acidKi500000.0 [1]
3-(Carboxyformamido)-5-(4-chlorophenyl)thiophene-2-carboxylic acidKi160000.0 [1]
(1R,2R,11R,14R,15S,18S,23S)-2,10,10,14,15,21,21-Heptamethyl-5,8-diazahexacyclo[12.12.0.02,11.04,9.015,24.018,23]hexacosa-4,6,8,24-tetraene-18-carboxylic acidIC5040000.0 [1]
(1R,2R,15R,18R,19S,22S,27S)-2,14,14,18,19,25,25-Heptamethyl-5,12-diazaheptacyclo[16.12.0.02,15.04,13.06,11.019,28.022,27]triaconta-4,6,8,10,12,28-hexaene-22-carboxylic acidIC5040000.0 [1]
2-(Carboxyformamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acidKi900000.0 [1]
2-[[4-[2-Acetamido-3-oxo-3-(pentylamino)propyl]naphthalen-1-yl]-oxaloamino]benzoic acidKi29600.0 [1]
4-(Carboxyformamido)biphenyl-3-carboxylic acidKi700000.0 [1]
3-(Carboxyformamido)-5-(4-isobutylphenyl)thiophene-2-carboxylic acidKi50000.0 [1]
3-(Carboxyformamido)-5-(4-fluorophenyl)thiophene-2-carboxylic acidKi110000.0 [1]
3-(Carboxyformamido)-5-(3-nitrophenyl)thiophene-2-carboxylic acidKi165000.0 [1]
(2S)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-3-phenyl-propionic acidIC503250.0 [1]
5-(3-Aminophenyl)-3-(carboxyformamido)thiophene-2-carboxylic acidKi113000.0 [1]
4-Phenyl-[1,2]naphthoquinoneIC502490.0 [1]
[[17-(Diphosphonomethyl)-26,28-dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9(27),10,12,15(26),16,18,21,23-dodecaenyl]-phosphonomethyl]phosphonic acidIC50100000.0 [1]
[(26,28-Dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaenyl)-phosphonomethyl]phosphonic acidIC50100000.0 [1]
4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]anilineIC50120000.0 [1]
4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]anilineIC50120000.0 [1]
5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-(4-methylphenyl)benzamideIC506950.0 [1]
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideIC5050000.0 [1]
2,4-Dihydroxy-6-propylbenzoic acidIC5020000.0 [1]
Isochroman mono-carboxylic acidIC501941.0 [1]
3-[5-[[2-Acetamido-3-[4-(2-carboxy-N-oxaloanilino)naphthalen-1-yl]propanoyl]amino]pentoxy]naphthalene-2-carboxylic acidKi1300.0 [1]
(5Z)-5-[[2-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-5-bromophenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC50100000.0 [1]
(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-20-phenyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acidIC5040000.0 [1]
(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acidIC5040000.0 [1]
2-[[4-[4-(3-Chloro-4-fluorophenyl)phenyl]-3-ethoxycarbonylthiophen-2-yl]carbamoyl]benzoic acidIC50100000.0 [1]
8-[2-[4-[(E)-2-Carboxyethenyl]phenyl]-1,3-thiazol-4-yl]dibenzofuran-4-carboxylic acidIC501981.0 [1]
[3-[3-[(3S)-3-(Methylcarbamoyl)-7-(sulfoamino)-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropyl]phenyl]sulfamic acidIC50500000.0 [1]
6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acidIC5010000.0 [1]
3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC5010000.0 [1]
6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acidIC5010000.0 [1]
[[3-(3-Cyclohexyl-2-hydroxyphenyl)phenyl]-difluoromethyl]phosphonic acidKi900000.0 [1]
[(S)-[4-[3-[(R)-(3,4-Dichlorophenyl)-hydroxymethyl]phenyl]phenyl]-hydroxymethyl]phosphonic acidKi360000.0 [1]
[(S)-[4-[3-[(S)-(3,4-Dichlorophenyl)-hydroxymethyl]phenyl]phenyl]-hydroxymethyl]phosphonic acidKi390000.0 [1]
2-[4-(Methylthio)-2-pyridinylmethylsulfinyl]-5-isopropoxy-1H-benzimidazoleIC5018200.0 [1]
2-(Oxaloamino)-6-(2-phenylethyl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acidKi2100000.0 [1]
(2R)-2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzofuran-11-yl)phenoxy]-3-phenylpropanoic acidIC50420.0 [1]
2-[4-[2-Acetamido-3-[4-(5-chloro-3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxopropyl]-2-ethyl-N-oxaloanilino]benzoic acidKi3000.0 [1]
6-Biphenyl-4-yl-4-oxo-4H-chromene-3-carbaldehydeIC501000000.0 [1]
2-[4-[[3-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC50120000.0 [1]
3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][1,2,4]triazine-5,7-diamineIC5012000.0 [1]
3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-diamineIC5028000.0 [1]
2-(1-Carboxyethoxy)-5-[(2S)-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-oxopropyl]benzoic acidKi30000.0 [1]
2-[4-[[2-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC50120000.0 [1]
4-Cyclohexyl-1,2-naphthoquinoneIC508990.0 [1]
2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzothiol-11-yl)phenoxy]acetic acidIC501500.0 [1]
2-(4-(7-(4-Methoxybenzoyl)cyclopenta[d][1,2]oxazin-4-yl)phenoxy)acetic acidIC5061700.0 [1]
Benzo[b]thieno[2,3-d]thiophene-2-carboxylic acid,3-(carboxymethoxy)-Ki1100000.0 [1]
2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acidIC5050000.0 [1]
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
2,4-Dimethoxy-6-propylbenzoic acidIC5020000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-f-lar-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-f-lar-inhibitors-ic50-ki.
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