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Receptor-type tyrosine-protein phosphatase beta Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
[[17-(Diphosphonomethyl)-26,28-dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9(27),10,12,15(26),16,18,21,23-dodecaenyl]-phosphonomethyl]phosphonic acidIC5032000.0 [1]
2-(Oxalyl-amino)-benzoic acidKi33000.0 [1]
2-(Oxalyl-amino)-4,5,6,7-tetrahydro-thieno[2,3-C]pyridine-3-carboxylic acidKi560000.0 [1]
(1-Amino-2-phenylethyl)phosphonic acidIC50139000.0 [1]
RazuprotafibIC500.0 [1]
Cefsulodin sodium saltIC50200000.0 [1]
[4-(Acetylamino)-3,5-dimethylphenoxy]acetic acidKi73200.0 [1]
5,6-Dichloro-1H-imidazo[4,5-b]pyrazine-2-carboxylic acidKi26000.0 [1]
CID 71734765IC50470.0 [1]
5-Iodo-2-(oxaloamino)benzoic acidKi17000.0 [1]
6-(Oxalyl-amino)-1H-indole-5-carboxylic acidKi6000.0 [1]
2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-C]pyran-3-carboxylic acidKi11000.0 [1]
2-(Carboxyformamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acidKi19000.0 [1]
1H-Indole-7-carboxylic acid, 6-[(carboxycarbonyl)amino]-Ki3600.0 [1]
2-(Carboxyformamido)thiophene-3-carboxylic acidKi18000.0 [1]
3-(Carboxyformamido)thiophene-2-carboxylic acidKi160000.0 [1]
CID 5179836IC50135000.0 [1]
5-((2-Hydroxy-1-naphthyl)diazenyl)-2-naphthalenesulfonic acidIC503900.0 [1]
[(26,28-Dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaenyl)-phosphonomethyl]phosphonic acidIC5013000.0 [1]
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideIC5059400.0 [1]
4-[5-(4-Benzyloxybenzylidene)-2,4-dioxothiazolidin-3-yl]methylbenzoic acidIC50400.0 [1]
[3-[3-[(3S)-3-(Methylcarbamoyl)-7-(sulfoamino)-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropyl]phenyl]sulfamic acidIC5020700.0 [1]
(2R)-2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzofuran-11-yl)phenoxy]-3-phenylpropanoic acidIC50500.0 [1]
[[4-[[4-[[4-[Difluoro(phosphono)methyl]phenyl]methoxy]phenoxy]methyl]phenyl]-difluoromethyl]phosphonic acidIC5015000.0 [1]
2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzothiol-11-yl)phenoxy]acetic acidIC50600.0 [1]
[[4-[[3-[[4-[Difluoro(phosphono)methyl]phenyl]methoxy]phenoxy]methyl]phenyl]-difluoromethyl]phosphonic acidIC5077000.0 [1]
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
p-Methylphosphonatocalix[4]areneIC503800.0 [1]
N'-[1-[4-(4-Fluorophenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]-N-(pyridin-3-ylmethyl)oxamideIC5050000.0 [1]
N-(Furan-2-ylmethyl)-N'-[1-[4-(4-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]oxamideIC5014400.0 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[[(2S)-2-methoxycarbonyl-4-methylpentanoyl]amino]ethyl]phenyl]sulfamic acidIC500.3 [1]
4-[2,4-Dioxo-5-(4-phenoxybenzylidene)thiazolidin-3-yl]methylbenzoic acidIC501100.0 [1]
5-[2-Cyclohexyl-4-[4-fluoro-2-(trifluoromethyl)phenyl]phenyl]-1,2-oxazole-3-carboxylic acidKi220.0 [1]
[(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-butyl}-phenyl)-difluoro-methyl]-phosphonic acidIC50342000.0 [1]
(7S)-7-[(1,1-Dioxo-1,2-benzothiazol-3-yl)oxymethyl]-2-(oxaloamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylic acidKi21000.0 [1]
[25,26,27,28-Tetrahydroxy-11,17,23-tris(phosphonomethyl)-2,8,14,20-tetrathiapentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaen-5-yl]methylphosphonic acidIC50130.0 [1]
2-(3-(Dihydroxymethyl)naphthalen-2-ylamino)-2-oxoacetic acidKi14000.0 [1]
BhansaliIC5031000.0 [1]
(4-(4-Bromo-3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl)difluoromethylphosphonic acidKi100000.0 [1]
Azane;[[4-[2-[[4-[difluoro(phosphono)methyl]phenyl]methoxy]ethoxymethyl]phenyl]-difluoromethyl]phosphonic acidIC50300000.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-[(4-sulfamoylphenyl)methyl]propyl]phenyl]sulfamic acidIC50430.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-[(3-sulfamoylphenyl)methyl]propyl]phenyl]sulfamic acidIC50300.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-2-[(4-methoxycarbonylphenyl)methyl]-3-oxopropyl]phenyl]sulfamic acidIC50410.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-2-[(3-methoxycarbonylphenyl)methyl]-3-oxopropyl]phenyl]sulfamic acidIC50290.0 [1]
Azane;4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-[[4-(sulfoamino)phenyl]methyl]propyl]benzoic acidIC50140.0 [1]
Azane;[4-[5-(benzenesulfonyl)-2,2-bis(methoxycarbonyl)pentyl]phenyl]sulfamic acidIC50150.0 [1]
Azane;[4-[6-methoxy-2,2-bis(methoxycarbonyl)-6-oxohexyl]phenyl]sulfamic acidIC50380.0 [1]
Azane;[4-[2-ethoxycarbonyl-2-methoxycarbonyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]butyl]phenyl]sulfamic acidIC5090.0 [1]
Azane;[4-[3-(3-methoxyphenyl)-2,2-bis(3-methyl-1,2,4-oxadiazol-5-yl)propyl]phenyl]sulfamic acidIC50230.0 [1]
Azane;[4-[4-ethoxy-2,2-bis(methoxycarbonyl)-4-oxobutyl]phenyl]sulfamic acidIC50230.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-(pyridin-4-ylmethyl)propyl]phenyl]sulfamic acidIC50570.0 [1]
Azane;[4-[2,2-bis(methoxycarbonyl)-5-phenylpentyl]phenyl]sulfamic acidIC50150.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-(phenylmethoxymethyl)propyl]phenyl]sulfamic acidIC50270.0 [1]
Azane;[4-[2,2-bis(methoxycarbonyl)-5-(1-phenyltetrazol-5-yl)sulfanylpentyl]phenyl]sulfamic acidIC50200.0 [1]
Azane;[4-[2,2-bis(methoxycarbonyl)-5-(1-phenyltetrazol-5-yl)sulfonylpentyl]phenyl]sulfamic acidIC5080.0 [1]
Azane;[4-[2,2-bis(methoxycarbonyl)-5-methylsulfonylpentyl]phenyl]sulfamic acidIC50420.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-2-[(4-methoxyphenyl)methyl]-3-oxopropyl]phenyl]sulfamic acidIC50390.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-2-[(3-methoxyphenyl)methyl]-3-oxopropyl]phenyl]sulfamic acidIC50330.0 [1]
Azane;[4-[3-methoxy-2-methoxycarbonyl-3-oxo-2-[[4-(sulfoamino)phenyl]methyl]propyl]phenyl]sulfamic acidIC5060.0 [1]
Azane;[3-[3-methoxy-2-methoxycarbonyl-3-oxo-2-[[4-(sulfoamino)phenyl]methyl]propyl]phenyl]sulfamic acidIC50100.0 [1]
Azane;[4-[2,2-bis(3-methyl-1,2,4-oxadiazol-5-yl)-3-[4-(sulfoamino)phenyl]propyl]phenyl]sulfamic acidIC5080.0 [1]
Azane;[4-(3-methoxy-2-methoxycarbonyl-3-oxopropyl)phenyl]sulfamic acidIC501000.0 [1]
Azane;[4-[2-ethoxycarbonyl-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenyl]sulfamic acidIC50450.0 [1]
Azane;[4-[2,2-bis(3-methyl-1,2,4-oxadiazol-5-yl)-5-phenylpentyl]phenyl]sulfamic acidIC5070.0 [1]
Azane;[4-[2-ethoxycarbonyl-3-methoxy-3-oxo-2-(phenylmethoxycarbonylamino)propyl]phenyl]sulfamic acidIC50400.0 [1]
Azane;[4-[3-(4-methoxyphenyl)-2,2-bis(3-methyl-1,2,4-oxadiazol-5-yl)propyl]phenyl]sulfamic acidIC50340.0 [1]
Azane;[4-[3-(3-cyanophenyl)-2,2-bis(3-methyl-1,2,4-oxadiazol-5-yl)propyl]phenyl]sulfamic acidIC50210.0 [1]
4-[(4-Anilino-9,10-dioxo-5,8-dihydroanthracen-1-yl)amino]benzenesulfonic acidIC504500.0 [1]
{4-[2-Benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopropyl]phenyl}sulfamic acidIC50320.0 [1]
Lyp-IN-1IC5012000.0 [1]
[(26,28-Dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaenyl)-hydroxy-phosphonomethyl]phosphonic acidIC5018000.0 [1]
[[26,28-Dihydroxy-17-[hydroxy(diphosphono)methyl]-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9(27),10,12,15(26),16,18,21,23-dodecaenyl]-hydroxy-phosphonomethyl]phosphonic acidIC5012000.0 [1]
[[4-[[2-[[4-[Difluoro(phosphono)methyl]phenyl]methoxy]phenoxy]methyl]phenyl]-difluoromethyl]phosphonic acidIC5077000.0 [1]
[4-[(2S)-2-[[5-[(2-Methyl-1,3-thiazol-4-yl)methyl]-1,3,4-thiadiazol-2-yl]amino]-2-(2-thiophen-2-yl-1,3-thiazol-4-yl)ethyl]phenyl]sulfamic acidIC500.01 [1]
[4-[(2S)-2-[3-(3-Chlorophenyl)propanoylamino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC500.2 [1]
[4-[(2S)-2-[(5-Phenyl-1,3,4-thiadiazol-2-yl)amino]-2-(2-phenyl-1,3-thiazol-4-yl)ethyl]phenyl]sulfamic acidIC5046.0 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[(2-phenylacetyl)amino]ethyl]phenyl]sulfamic acidIC500.16 [1]
[4-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC501.0 [1]
[4-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-2-(4-tert-butyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC500.3 [1]
[4-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-2-(4-thiophen-3-yl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC500.24 [1]
[4-[(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-2-(4-phenyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5049.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5085.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-(4-ethoxycarbonyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC50584.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-(4-phenyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5042.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]ethyl]phenyl]sulfamic acidIC50110.0 [1]
[4-[(2S)-2-[4-(2,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-2-(2,2-dimethylpropanoylamino)ethyl]phenyl]sulfamic acidIC5086.0 [1]
[4-[(2S)-2-(4-Benzyl-1,3-thiazol-2-yl)-2-(2,2-dimethylpropanoylamino)ethyl]phenyl]sulfamic acidIC50113.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-[4-[(3-methoxyphenyl)methyl]-1,3-thiazol-2-yl]ethyl]phenyl]sulfamic acidIC50132.0 [1]
[4-[(2S)-2-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]-2-(2,2-dimethylpropanoylamino)ethyl]phenyl]sulfamic acidIC50138.0 [1]
[4-[(2S)-2-(2,2-Dimethylpropanoylamino)-2-(5-methyl-4-phenyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5098.0 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[[(2S)-2-[(3-methoxy-3-oxopropanoyl)amino]-3-phenylpropanoyl]amino]ethyl]phenyl]sulfamic acidIC500.3 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[[2-(2-fluorophenyl)acetyl]amino]ethyl]phenyl]sulfamic acidIC5012.0 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[[2-(3-fluorophenyl)acetyl]amino]ethyl]phenyl]sulfamic acidIC500.3 [1]
[4-[(2S)-2-[[2-(2,3-Difluorophenyl)acetyl]amino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5028.0 [1]
[4-[(2S)-2-[[2-(3,4-Difluorophenyl)acetyl]amino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5075.0 [1]
[4-[(2S)-2-[[2-(2-Chlorophenyl)acetyl]amino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5056.0 [1]
[4-[(2S)-2-[[2-(3-Chlorophenyl)acetyl]amino]-2-(4-ethyl-1,3-thiazol-2-yl)ethyl]phenyl]sulfamic acidIC5033.0 [1]
[4-[(2S)-2-(4-Ethyl-1,3-thiazol-2-yl)-2-[[2-(2-methoxyphenyl)acetyl]amino]ethyl]phenyl]sulfamic acidIC5014.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Receptor-type tyrosine-protein phosphatase beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Receptor-type tyrosine-protein phosphatase beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-beta-inhibitors-ic50-ki.
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