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Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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CID 6077765IC503200.0 [1], 10800.0 [2]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanideIC502400.0 [1], 2700.0 [2]
(2R)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehydeIC503300.0 [1], 4200.0 [2], 5500.0 [3]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC502400.0 [1]
(1E)-N-(3-Chloroanilino)-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanideIC50150000.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC505700.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanideIC5011600.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanideIC507800.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC509700.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC504300.0 [1]
(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanideIC508900.0 [1]
(1E)-2-(5-Cyclohexyl-1,2-oxazol-3-yl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC502600.0 [1]
(1E)-2-(5-Cyclopropyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanideIC504100.0 [1]
(1E)-2-(5-Cyclohexyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanideIC504000.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC505400.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-naphthalen-2-yl-2-oxoethanimidoyl cyanideIC5011300.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanideIC5012400.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanideIC506400.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-(3,4-dimethoxyphenyl)-2-oxoethanimidoyl cyanideIC50300000.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-[4-(morpholin-4-ylmethyl)phenyl]-2-oxoethanimidoyl cyanideIC5014600.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC506100.0 [1]
(1E)-2-(4-Cyclohexylphenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC5032400.0 [1]
(1E)-2-(4-Tert-butylphenyl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanideIC5024400.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC505600.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-quinolin-6-ylethanimidoyl cyanideIC5019600.0 [1]
(1E)-2-(4-Chlorophenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC50300000.0 [1]
(1E)-2-(4-Tert-butylphenyl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC5050800.0 [1]
(1E)-2-(3-Chlorophenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanideIC50300000.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-[4-(piperidin-1-ylmethyl)phenyl]ethanimidoyl cyanideIC5039400.0 [1]
(1E)-2-(4-Tert-butylphenyl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanideIC5013900.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-[4-(trifluoromethoxy)phenyl]ethanimidoyl cyanideIC5040900.0 [1]
(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC509000.0 [1]
(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5010200.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanideIC508500.0 [1]
(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC505600.0 [1]
(1E)-N-(3-Chloroanilino)-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC509900.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloroanilino)-2-oxoethanimidoyl cyanideIC5013200.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanideIC5013100.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanideIC5018900.0 [1]
(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanideIC509500.0 [1]
(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC507300.0 [1]
(1E)-N-(3-Chloroanilino)-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5038600.0 [1]
(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC504200.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC503000.0 [1]
(1E)-N-(3-Chloroanilino)-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5011400.0 [1]
(1E)-2-[5-(4-Chlorophenyl)-1,2-oxazol-3-yl]-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC507800.0 [1]
(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanideIC507200.0 [1]
(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC5010200.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC504600.0 [1]
(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-(3-chloroanilino)-2-oxoethanimidoyl cyanideIC508600.0 [1]
(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC505600.0 [1]
(1E)-N-(3-Chloroanilino)-2-[5-(4-chlorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5077600.0 [1]
(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-tert-butylphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5011900.0 [1]
(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanideIC502400.0 [1]
(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-chlorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5011400.0 [1]
(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC5012700.0 [1]
(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanideIC503600.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3,5-bis(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC506700.0 [1]
(1E)-2-(1,2-Benzoxazol-3-yl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanideIC502700.0 [1]
(2R)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothialdehydeIC5017600.0 [1]
(2S)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothialdehydeIC50100000.0 [1]
Methyl 4-[(2E)-2-cyano-2-[(3,5-dichlorophenyl)hydrazinylidene]acetyl]benzoateIC5029300.0 [1]
(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-(4-phenylphenyl)ethanimidoyl cyanideIC50300000.0 [1]
(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-(5-tert-butyl-1,2-oxazol-3-yl)-2-oxoethanimidoyl cyanideIC505700.0 [1]
(2S)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehydeIC5031300.0 [1]
Items per page: 1 - 10 of 65
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References

This online tool may be cited as follows

MLA

"Quest Database™ Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/rap-guanine-nucleotide-exchange-factor-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/rap-guanine-nucleotide-exchange-factor-3-inhibitors-ic50-ki.
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