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Quinone reductase 2 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
ResveratrolIC50913.0 [1]
ResveratrolKi88.0 [1]
MelatoninIC506600.0 [1], 11300.0 [2]
MelatoninKi27.6 [1], 56.9 [2]
ImatinibIC5043.0 [1], 82.0 [2], 400.0 [3]
ImatinibKi39.0 [1]
DabigatranIC5010000.0 [1], 11000.0 [2]
DabigatranKi60000.0 [1]
5-Methoxycarbonylamino-N-acetyltryptamineIC502.7 [1], 57.54 [2], 58.0 [3]
N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamideIC502.82 [1], 5700.0 [2]
N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamideKi2.8 [1]
Acetamide,n-[2-(2-iodo-5-methoxy-1-methyl-4-nitro-1h-indol-3-yl)ethyl]-IC500.13 [1]
Acetamide,n-[2-(2-iodo-5-methoxy-1-methyl-4-nitro-1h-indol-3-yl)ethyl]-Ki0.13 [1], 0.3 [2]
Dabigatran ethyl esterIC50800.0 [1], 1500.0 [2]
Dabigatran ethyl esterKi900.0 [1]
Acetic acid;4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamideIC5035.0 [1], 72.0 [2], 630.0 [3]
Acetic acid;4-(5-phenylfuran-2-yl)benzenecarboximidamideIC5068.0 [1], 139.0 [2], 140.0 [3]
NilotinibIC50381.0 [1], 1800.0 [2]
2-IodomelatoninIC501100.0 [1]
2-IodomelatoninKi6.5 [1]
5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-oneIC50126.0 [1], 148.0 [2]
5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-1-methyl-6H-imidazo(4,5,1-de)acidin-6-oneIC5016.0 [1], 54.0 [2]
10-[2-(Dimethylamino)ethylamino]-5-hydroxy-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-8-oneIC5083.0 [1], 296.0 [2]
N-[2-(5-Methoxy-1-methyl-4-nitro-1H-indol-3-yl)-ethyl]-acetamideIC500.31 [1]
N-[2-(5-Methoxy-1-methyl-4-nitro-1H-indol-3-yl)-ethyl]-acetamideKi0.31 [1]
5-((2-(Dimethylamino)ethyl)amino)-8-hydroxy-1-methyl-6H-imidazo(4,5,1-de)acridin-6-oneIC5050.0 [1], 90.0 [2]
10-[2-(Dimethylamino)ethylamino]-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,6,9,11,13(16),14-heptaen-8-oneIC50115.0 [1], 830.0 [2]
Acetamide,n-[2-(2-iodo-5-methoxy-4-nitro-1h-indol-3-yl)ethyl]-IC500.2 [1]
Acetamide,n-[2-(2-iodo-5-methoxy-4-nitro-1h-indol-3-yl)ethyl]-Ki0.18 [1]
N-[2-(5-Methoxy-4-nitro-1H-indol-3-yl)ethyl]acetamideIC501.2 [1]
N-[2-(5-Methoxy-4-nitro-1H-indol-3-yl)ethyl]acetamideKi1.1 [1]
Acetamide,n-[2-(2-iodo-5-methoxy-1-methyl-1h-indol-3-yl)ethyl]-IC500.09 [1]
Acetamide,n-[2-(2-iodo-5-methoxy-1-methyl-1h-indol-3-yl)ethyl]-Ki0.09 [1]
5-{[2-(Dimethylamino)ethyl]amino}-8-Methoxy-6h-Imidazo[4,5,1-De]acridin-6-OneIC5059.0 [1], 3200.0 [2]
N-(2-(7-Sulfamoylnaphthalen-1-yl)ethyl)acetamideIC5032.0 [1], 32.36 [2]
N-(2-(7-(N-Methylsulfamoyl)naphthalen-1-yl)ethyl)furan-2-carboxamideIC509.1 [1], 9.12 [2]
N-(2-(7-(Methylsulfonyl)naphthalen-1-yl)ethyl)acetamideIC5020.89 [1], 21.0 [2]
10-[2-(Dimethylamino)ethylamino]-15-methyl-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,6,9,11,13(16),14-heptaen-8-oneIC5090.0 [1], 323.0 [2]
N-[3-(Cyanomethyl)-2-oxo-2,3-dihydro-1H-indol-5-yl]acetamideIC5014100.0 [1]
N-[2-(5-Acetamido-3-hydroxy-2-oxo-1H-indol-3-yl)ethyl]acetamideIC50200.0 [1]
N-[2-(5-Acetamido-2-oxo-1,3-dihydroindol-3-yl)ethyl]acetamideIC5020700.0 [1]
N-[3-(Cyanomethyl)-1-methyl-2-oxo-3H-indol-5-yl]acetamideIC507000.0 [1]
N-(2-(7-(Methylsulfinyl)naphthalen-1-yl)ethyl)acetamideIC5037.0 [1], 37.15 [2]
N-(2-(7-(Methylthio)naphthalen-1-yl)ethyl)acetamideIC5018.0 [1], 18.2 [2]
Acetic acid;4-[5-(4-ethylphenyl)furan-2-yl]benzenecarboximidamideIC50202.0 [1], 312.0 [2]
Acetic acid;4-[5-(4-methoxyphenyl)furan-2-yl]benzenecarboximidamideIC50107.0 [1], 141.0 [2]
Acetic acid;4-[5-(4-tert-butylphenyl)furan-2-yl]benzenecarboximidamideIC50509.9 [1], 712.0 [2]
Acetic acid;4-[5-(3-nitrophenyl)furan-2-yl]benzenecarboximidamideIC5014.5 [1], 28.0 [2]
Acetic acid;4-[5-(4-nitrophenyl)furan-2-yl]benzenecarboximidamideIC5015.2 [1], 24.0 [2]
Acetic acid;4-(5-phenyl-1H-pyrrol-2-yl)benzenecarboximidamideIC50332.0 [1], 832.0 [2]
Acetic acid;4-(1-methyl-5-phenylpyrrol-2-yl)benzenecarboximidamideIC50410.0 [1], 943.0 [2]
2-[(5-Methoxy-8-oxo-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-10-yl)amino]-N,N-dimethylethanamine oxideIC5014.0 [1], 98.0 [2]
4-[5-(3-Fluorophenyl)furan-2-yl]benzenecarboximidamideIC5098.0 [1], 111.0 [2]
4-[5-(4-Fluorophenyl)furan-2-yl]benzenecarboximidamideIC50505.0 [1], 836.0 [2]
4-[5-(4-Bromophenyl)furan-2-yl]benzenecarboximidamideIC5027.0 [1], 185.0 [2]
4-[5-(4-Methylphenyl)furan-2-yl]benzenecarboximidamideIC5072.0 [1], 110.0 [2]
ChloroquineIC501500.0 [1]
PrazosinIC507.8 [1]
PrimaquineIC507500.0 [1]
PterostilbeneIC505100.0 [1]
FuramidineIC5035.0 [1]
(E)-3,5,4'-TrimethoxystilbeneIC5014600.0 [1]
PseudoisocyanineIC502700.0 [1]
1,3-NaphthalenediolIC503300.0 [1]
4-(4-Butylpiperidin-1-yl)-1-o-tolylbutan-1-oneKi1000.0 [1]
1-MethoxyphenazineIC5031100.0 [1]
4-Methylquinolin-2-olIC50500000.0 [1]
(E)-3,3',4,5'-TetramethoxystilbeneIC5037100.0 [1]
6,8-Diamino-7-Chloro-1-Methyl-2-Oxo-1,2-Dihydropyrrolo[4,3,2-De]quinoline-4-CarboxamideIC5061.0 [1]
N-(2-(5-Methoxybenzofuran-3-yl)ethyl)acetamideIC5064.57 [1]
3,5-Dimethoxy-4'-fluorostilbeneIC504600.0 [1]
4-(4-Hydroxystyryl)benzene-1,2-diolIC506000.0 [1]
(E)-3'-Hydroxy-3,5,4'-trimethoxystilbeneIC5015000.0 [1]
1,4-Dimethylquinolin-2(1h)-oneIC5018200.0 [1]
2-MethoxyphenazineIC5015300.0 [1]
CasimiroinIC5054100.0 [1]
4-[2-(3,5-Dimethoxyphenyl)ethenyl]benzeneamineIC501700.0 [1]
1-Methoxy-7,8-dimethylphenazineIC5011700.0 [1]
3,4-Dimethoxy-N-(2-naphthyl)benzamideIC505500.0 [1]
Propanamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-2-methyl-IC5043.65 [1]
3,4-Dimethyl-2,5-bis(4-amidinophenyl)furanIC5050.0 [1]
N-[1-[3-(3-Oxo-1,4-benzoxazin-4-yl)propyl]piperidin-4-yl]-2-phenylacetamideKi1000.0 [1]
5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-oneIC503840.0 [1]
3,4-Dihydroxy-4'-methoxystilbeneIC509300.0 [1]
2-ChloromelatoninIC5013000.0 [1]
5,8-Dimethoxy-4-methylquinolin-2(1H)-oneIC5010800.0 [1]
Benzamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-IC5028.84 [1]
10-[2-(Diethylamino)ethylamino]-8-hydroxy-4,5-dimethoxy-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,7,9,11,13(16),14-heptaen-6-oneIC506.0 [1]
10-[2-(Diethylamino)ethylamino]-8-hydroxy-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,5,7,9,11,13(16),14-heptaen-4-oneIC50953.0 [1]
10-[2-(Diethylamino)ethylamino]-5-methoxy-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-8-oneIC501000.0 [1]
10-[2-(Dimethylamino)ethylamino]-1,14,15-triazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,6,9,11,13(16),14-heptaen-8-oneIC501833.0 [1]
3-(3,4-Dichlorophenyl)-1-(2-(3,5-diphenyl-1H-pyrazol-1-yl)-4-methylthiazol-5-yl)prop-2-en-1-oneIC504900.0 [1]
N-[2-(6-Methoxynaphthalen-1-yl)ethyl]cyclobutanecarboxamideIC5070.79 [1]
Rac-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamideKi686.0 [1]
(Z)-3-(3,5-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-acrylonitrileIC5031600.0 [1]
5-Quinoxalinol, 6,8-dibromo-2,3-dimethyl-IC502900.0 [1]
7,8-Dichloro-1-hydroxyphenazineIC50480.0 [1]
5-((3-Diethylamino)propyl)amino-8-hydroxy-6H-imidazo(4,5,1-de)acridin-6-oneIC50597.0 [1]
10-[2-(Dimethylamino)ethylamino]-5-methoxy-15-methyl-1,14-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-8-oneIC5046.0 [1]
(E)-4'-Amino-3,4,5-trimethoxystilbeneIC50270.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Quinone reductase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/quinone-reductase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Quinone reductase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/quinone-reductase-2-inhibitors-ic50-ki.
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