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Purinergic receptor P2Y14 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-[2-(2-Tert-butylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]ureaKi3500.0 [1]
4-(4-Piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC507.96 [1]
3-[5-(3-Aminopropylcarbamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC50169.0 [1]
1-[2-(2-Propan-2-ylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]ureaKi3300.0 [1]
1-(4-Tert-butylphenyl)-3-[2-(2-propan-2-ylphenoxy)pyridin-3-yl]ureaKi15000.0 [1]
1-[2-(2-Tert-butylphenoxy)pyridin-3-yl]-3-(4-tert-butylphenyl)ureaKi5950.0 [1]
4-[4-[1-[4-[1-(6-Aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC5025.4 [1]
4-[4-(1-Hex-5-ynylpiperidin-4-yl)phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC50763.0 [1]
Sodium;3-(5-carbamoylpyrazin-2-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC50566.0 [1]
3-[5-(4-Hydroxybutylsulfamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC508420.0 [1]
5-[3-Bromo-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]phenyl]-2H-tetrazoleIC5033100.0 [1]
3-[5-[4-[(2-Methylpropan-2-yl)oxycarbonylamino]butylsulfamoyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5013600.0 [1]
3-[5-(3-Aminopropylsulfamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC50756.0 [1]
3-[5-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]propylcarbamoyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC502280.0 [1]
3-[5-(2-Aminoethylsulfamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC502260.0 [1]
Sodium;3-[4-(ethylcarbamoyl)phenyl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC50899.0 [1]
3-(4-Carbamoylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acid;N,N-diethylethanamineIC50269.0 [1]
3-(5-Carbamoylfuran-2-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acid;N,N-diethylethanamineIC503110.0 [1]
N,N-Diethylethanamine;3-(5-sulfamoylthiophen-2-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC506440.0 [1]
Sodium;3-(5-carbamoylpyridin-2-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC50516.0 [1]
N-(3-Aminopropyl)-5-[3-(2H-tetrazol-5-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]phenyl]thiophene-2-carboxamideIC501190.0 [1]
3-(5-Piperazin-1-ylsulfonylthiophen-2-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC501510.0 [1]
Sodium;3-[4-(methylcarbamoyl)phenyl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC50563.0 [1]
4-[4-[1-[4-[1-(6-Acetamidohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC5083.5 [1]
Sodium;3-(6-carbamoylpyridin-3-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC501410.0 [1]
4-[3-(2H-Tetrazol-5-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]phenyl]benzamideIC502430.0 [1]
3-[5-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]propylsulfamoyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC509330.0 [1]
3-[5-(Piperazine-1-carbonyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5012600.0 [1]
N,N-Diethylethanamine;3-(4-sulfamoylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC50608.0 [1]
Sodium;3-[4-(propylcarbamoyl)phenyl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC501490.0 [1]
4-[4-[1-[4-[1-[6-[(2-Methylpropan-2-yl)oxycarbonylamino]hexyl]triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC50133.0 [1]
3-Bromo-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5026800.0 [1]
3-(4-Piperazin-1-ylsulfonylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC501640.0 [1]
3-[4-[4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]sulfonylphenyl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5050000.0 [1]
3-[5-(4-Aminobutylsulfamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC502180.0 [1]
3-[5-[2-[(2-Methylpropan-2-yl)oxycarbonylamino]ethylsulfamoyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC505920.0 [1]
3-[5-(3-Aminopropylcarbamoyl)thiophen-3-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC501750.0 [1]
3-[4-(3-Aminopropylcarbamoyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC50735.0 [1]
3-[5-[4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazine-1-carbonyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5053000.0 [1]
3-Hydroxy-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5016400.0 [1]
Sodium;3-[4-(tert-butylcarbamoyl)phenyl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoateIC507530.0 [1]
3-[5-(Piperazin-1-ylmethyl)thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC501960.0 [1]
3-[5-[[4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]methyl]thiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5067200.0 [1]
4-[4-[3-(2H-Tetrazol-5-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]phenyl]phenyl]piperidineIC50958.0 [1]
3-[5-[4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]sulfonylthiophen-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5054700.0 [1]
4-Hydroxy-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acidIC503200.0 [1]
3-[5-(3-Aminopropylcarbamoyl)furan-2-yl]-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]benzoic acidIC5010900.0 [1]
N-Tert-butyl-4-[3-(2H-tetrazol-5-yl)-5-[4-[4-(trifluoromethyl)phenyl]triazol-1-yl]phenyl]benzamideIC5020700.0 [1]
1-[2-(2-Tert-butylphenyl)sulfanylpyridin-3-yl]-3-(4-methylphenyl)ureaKi2350.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Purinergic receptor P2Y14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/purinergic-receptor-p2y14-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Purinergic receptor P2Y14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/purinergic-receptor-p2y14-inhibitors-ic50-ki.
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