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Protoporphyrinogen oxidase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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SulfentrazoneKi720.0 [1]
Ethyl [5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanylformateKi330.0 [1]
Ethyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi250.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1010.0 [1], 1070.0 [2]
Ethyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi2020.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi1690.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi1350.0 [1]
5-Tert-butyl-3-(6-chloro-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2-oneKi8610.0 [1]
Methyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi3990.0 [1]
Ethyl [5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanylformateKi720.0 [1], 1300.0 [2]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1580.0 [1]
Ethyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi320.0 [1]
Ethyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi360.0 [1], 700.0 [2]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi1540.0 [1]
Propyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi700.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi1420.0 [1]
Propan-2-yl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1170.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetateKi6960.0 [1]
Ethyl 4-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi5830.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi8130.0 [1]
Ethyl 3-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi1690.0 [1]
3-(6-Bromo-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-5-tert-butyl-1,3,4-oxadiazol-2-oneKi11120.0 [1]
AcifluorfenKi1710.0 [1]
OxadiazonKi2930.0 [1]
Ethyl [5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanylformateKi40.0 [1]
2-(4-Chloro-2-fluoro-5-prop-2-enoxyphenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi120.0 [1]
2-(4-Chloro-2-fluoro-5-propoxyphenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi95.0 [1]
4-ChlorophthalimideKi87870.0 [1]
5-Tert-butyl-3-[6-chloro-2-(3,3-dichloroprop-2-enylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2-oneKi10240.0 [1]
Tert-butyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi840.0 [1]
Methyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1070.0 [1]
5-Tert-butyl-3-(6-chloro-2-prop-2-enylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2-oneKi3110.0 [1]
Propan-2-yl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi2170.0 [1]
Propyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi980.0 [1]
Methyl [5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanylformateKi720.0 [1]
Tert-butyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1590.0 [1]
5-Tert-butyl-3-(6-fluoro-2-prop-2-enylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2-oneKi15920.0 [1]
5-Tert-butyl-3-[2-(3,3-dichloroprop-2-enylsulfanyl)-6-fluoro-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2-oneKi10920.0 [1]
Methyl (E)-4-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]but-2-enoateKi7480.0 [1]
Methyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetateKi7460.0 [1]
Propan-2-yl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetateKi5970.0 [1]
Propyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetateKi3100.0 [1]
3-[6-Bromo-2-(3,3-dichloroprop-2-enylsulfanyl)-1,3-benzothiazol-5-yl]-5-tert-butyl-1,3,4-oxadiazol-2-oneKi18630.0 [1]
Propan-2-yl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1260.0 [1]
5-Tert-butyl-3-(6-fluoro-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-thiadiazol-2-oneKi9730.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi5820.0 [1]
Ethyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi17700.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi340.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi5890.0 [1]
Ethyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi8670.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi34400.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi43500.0 [1]
Ethyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi9260.0 [1]
Ethyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi1280.0 [1]
5-Tert-butyl-3-(6-chloro-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-thiadiazol-2-oneKi21400.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi173000.0 [1]
5-Tert-butyl-3-(6-fluoro-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2-oneKi1920.0 [1]
Ethyl [5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanylformateKi200.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi12000.0 [1]
Ethyl 3-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoateKi27500.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi1580.0 [1]
Methyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi3050.0 [1]
Propyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetateKi1310.0 [1]
3-(6-Bromo-2-prop-2-ynylsulfanyl-1,3-benzothiazol-5-yl)-5-tert-butyl-1,3,4-thiadiazol-2-oneKi20700.0 [1]
Ethyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoateKi3460.0 [1]
Ethyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetateKi15600.0 [1]
Ethyl 4-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3-yl)-1,3-benzothiazol-2-yl]sulfanyl]butanoateKi245000.0 [1]
2-(4-Bromo-2-fluoro-5-hydroxyphenyl)-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi19350.0 [1]
Ethyl 2-[2-chloro-5-(1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)-4-fluorophenoxy]acetateKi15240.0 [1]
2-[4-Chloro-2-fluoro-5-[(3-fluorophenyl)methoxy]phenyl]-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi780.0 [1]
2-(4-Chloro-2-fluoro-5-methoxyphenyl)-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dioneKi8220.0 [1]
Ethyl 2-[2-chloro-4-fluoro-5-(1-hydroxy-3-oxo-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl)phenoxy]propanoateKi48070.0 [1]
2-(4-Chloro-5-ethynoxy-2-fluorophenyl)-3-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-isoindol-1-oneKi63630.0 [1]
2-(3-Amino-4-chlorophenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi27640.0 [1]
2-(4-Bromo-2-fluoro-5-hydroxyphenyl)-3-prop-2-enoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi41350.0 [1]
2-[4-Chloro-5-[(3-chlorophenyl)methoxy]-2-fluorophenyl]-3-methoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi1030.0 [1]
2-(4-Chloro-2-fluoro-5-methoxyphenyl)-3-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-isoindol-1-oneKi130970.0 [1]
2-(2,4-Dichloro-5-propoxyphenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi300.0 [1]
2-(2,4-Dichloro-5-prop-2-enoxyphenyl)-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi7450.0 [1]
2-(4-Chloro-2-ethoxy-5-nitrophenyl)-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi358600.0 [1]
2-(4-Chloro-2-fluoro-5-methoxyphenyl)-3-methoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi4490.0 [1]
2-(4-Chloro-2-fluoro-5-prop-2-enoxyphenyl)-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi1030.0 [1]
2-(2,4-Dichloro-5-ethoxyphenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi670.0 [1]
2-[4-Chloro-5-[(3-chlorophenyl)methoxy]-2-fluorophenyl]-3-hydroxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi530.0 [1]
2-(4-Chloro-5-ethoxy-2-fluorophenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi200.0 [1]
2-[4-Chloro-5-[(3-chlorophenyl)methoxy]-2-fluorophenyl]-3-prop-2-enoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi66580.0 [1]
2-(4-Chloro-2-fluoro-5-prop-2-enoxyphenyl)-3-prop-2-enoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi33130.0 [1]
2-(4-Chloro-5-ethoxy-2-fluorophenyl)-3-prop-2-enoxy-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi7020.0 [1]
Ethyl 2-[2-chloro-5-(1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)-4-fluorophenoxy]propanoateKi3300.0 [1]
2-(4-Chloro-5-cyclopentyloxy-2-fluorophenyl)-3-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-isoindol-1-oneKi24640.0 [1]
2-(4-Chloro-2-fluoro-5-propan-2-yloxyphenyl)-3-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-isoindol-1-oneKi47350.0 [1]
Ethyl 2-[2-chloro-4-fluoro-5-(1-hydroxy-3-oxo-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl)phenoxy]acetateKi123780.0 [1]
2-(4-Chloro-2-fluoro-5-prop-2-enoxyphenyl)-3-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-isoindol-1-oneKi44830.0 [1]
2-(4-Chloro-2-fluoro-5-propan-2-yloxyphenyl)-4,5,6,7-tetrahydro-3H-isoindol-1-oneKi690.0 [1]
Items per page: 1 - 10 of 94
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References

This online tool may be cited as follows

MLA

"Quest Database™ Protoporphyrinogen oxidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 19 Feb. 2025, https://www.aatbio.com/data-sets/protoporphyrinogen-oxidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 19). Quest Database™ Protoporphyrinogen oxidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protoporphyrinogen-oxidase-inhibitors-ic50-ki.
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