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Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
CID 5777336IC501000.0 [1]
CID 5777336Ki690.0 [1]
Linoleic acidIC50100000.0 [1]
EnoxoloneIC50300000.0 [1]
Caffeic acidIC50100000.0 [1]
Estramustine phosphateIC50152700.0 [1]
CelastrolIC5075700.0 [1]
ImperatorinIC50100000.0 [1]
Polyestradiol phosphateIC50300000.0 [1]
2,3-Dihydroxypropyl decanoateIC50100000.0 [1]
FlAsHIC50250.0 [1]
8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acidIC507745.0 [1]
Stigmasterol glucosideIC5082500.0 [1]
Dotriacontanoic acidIC50100000.0 [1]
cis-12-Octadecenoic acidIC50100000.0 [1]
CID 25262525IC5032100.0 [1]
Cefsulodin sodium saltIC50250000.0 [1]
6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acidIC5050000.0 [1]
2-[4-[(Z)-[5-(4-Chlorophenyl)-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acidIC501300.0 [1]
CID 71734765IC503000.0 [1]
6-(Hydroxymethyl)pyridin-3-olIC50100000.0 [1]
4-[5-[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxobutanoic acidIC5047800.0 [1]
(9Z)-Heptadeca-1,9-dien-4,6-diyne-3,8,11-triolIC50100000.0 [1]
2-[(5Z)-5-[[3-[4-[(2-Fluorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acidIC50870.0 [1]
6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acidIC502100.0 [1]
3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC503300.0 [1]
6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acidIC501900.0 [1]
3-Chloro-N-(5-methyl-1,3-benzothiazol-2-yl)-1-benzothiophene-2-carboxamideIC508000.0 [1]
2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acidIC508700.0 [1]
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
8Z,11Z-Heptadecadienoic AcidIC50100000.0 [1]
CID 1435211IC5040000.0 [1]
2-(3-Cyano-5,8-dimethylquinolin-2-yl)sulfanyl-N-(2-ethyl-6-methylphenyl)acetamideIC5010000.0 [1]
2-(3-Cyano-7-methoxyquinolin-2-yl)sulfanyl-N-(2,3-dimethylphenyl)acetamideIC5015000.0 [1]
CID 16220825IC501000000.0 [1]
CID 16220826IC501000000.0 [1]
CID 16220827IC50211000.0 [1]
CID 16221752IC501000000.0 [1]
CID 16221754IC501000000.0 [1]
CID 16221756IC501000000.0 [1]
CID 16221757IC507500.0 [1]
3-[(1-Cyclopentyltetrazol-5-yl)-piperidin-1-ylmethyl]-6-methyl-1H-quinolin-2-oneIC5075000.0 [1]
3-[(1-Cyclopentyltetrazol-5-yl)-(4-phenylpiperazin-1-yl)methyl]-6-methyl-1H-quinolin-2-oneIC5075000.0 [1]
3-[(1-Cyclopentyltetrazol-5-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-6-methyl-1H-quinolin-2-oneIC5075000.0 [1]
3-[[4-(1,3-Benzothiazol-2-yl)piperazin-1-yl]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC5075000.0 [1]
3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyrilIC5020000.0 [1]
2-[1-(4-Methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-1-(2-methyl-2,3-dihydroindol-1-yl)ethanoneIC5018000.0 [1]
N-(1,3-Benzodioxol-5-yl)-2-(3-cyano-7-methylquinolin-2-yl)sulfanylacetamideIC5012000.0 [1]
N-(3-Chlorophenyl)-2-(3-cyano-8-methylquinolin-2-yl)sulfanylacetamideIC5022000.0 [1]
2-(3-Cyano-7,8-dimethylquinolin-2-yl)sulfanyl-N-cyclohexylacetamideIC508000.0 [1]
2-(3-Cyano-7,8-dimethylquinolin-2-yl)sulfanyl-N-(3,4-dimethylphenyl)acetamideIC5020000.0 [1]
2-(3-Cyano-6,8-dimethylquinolin-2-yl)sulfanyl-N-(4-ethoxyphenyl)acetamideIC5016000.0 [1]
2-[(5,6-Dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamideIC509000.0 [1]
2-[4-[[4-[(4-Oxalophenoxy)methyl]-3-[[4-(4-phenylphenoxy)phenyl]carbamoyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC5021000.0 [1]
2-[4-[[4-[(4-Oxalophenoxy)methyl]-3-[[4-[4-(trifluoromethylsulfanyl)phenoxy]phenyl]carbamoyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC5053000.0 [1]
2-[4-[[3-[[4-(4-Ethylphenoxy)phenyl]carbamoyl]-4-[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC5052000.0 [1]
2-[4-[[3-[[4-(4-Hexylphenoxy)phenyl]carbamoyl]-4-[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acidIC5028000.0 [1]
3-[1-[4-[(4-Chloronaphthalen-1-yl)amino]-4-oxobutyl]triazol-4-yl]-6-hydroxy-2-(4-methylphenyl)-1-benzofuran-5-carboxylic acidIC503690.0 [1]
6-Hydroxy-2-(4-methoxyphenyl)-3-[1-[4-(naphthalen-1-ylamino)-4-oxobutyl]triazol-4-yl]-1-benzofuran-5-carboxylic acidIC503700.0 [1]
Methyl 3-[1-[4-[(4-chloronaphthalen-1-yl)amino]-4-oxobutyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylateIC5032000.0 [1]
6-Hydroxy-2-(4-methylphenyl)-3-[1-[4-(naphthalen-1-ylamino)-4-oxobutyl]triazol-4-yl]-1-benzofuran-5-carboxylic acidIC504070.0 [1]
6-Hydroxy-3-[1-[4-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-oxobutyl]triazol-4-yl]-2-(3-methylphenyl)-1-benzofuran-5-carboxylic acidIC506360.0 [1]
10Z,13Z-Nonadecadienoic acidIC50100000.0 [1]
12Z,15Z-Heneicosadienoic acidIC5044800.0 [1]
2-[4-[(Z)-[6-Ethoxycarbonyl-5-(3-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acidIC504600.0 [1]
2-[4-[(Z)-[5-(2-Chlorophenyl)-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]-2-methoxy-6-methylphenoxy]acetic acidIC503700.0 [1]
(18Z,21Z)-Heptacosa-18,21-dienoic acidIC50100000.0 [1]
[2-Hydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] dodecanoateIC50100000.0 [1]
2-[(5Z)-4-Oxo-5-[[1-phenyl-3-(4-phenylmethoxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acidIC501500.0 [1]
2-[4-[(Z)-[6-Ethoxycarbonyl-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acidIC501800.0 [1]
2-[(5Z)-5-[[3-[4-[(4-Chlorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acidIC50620.0 [1]
2-[(5Z)-4-Oxo-5-[[1-phenyl-3-(4-piperidin-1-ylsulfonylphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acidIC502400.0 [1]
2-[(5Z)-5-[[3-[4-[(2-Chlorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acidIC501200.0 [1]
Ethyl (2Z)-7-methyl-3-oxo-5-thiophen-2-yl-2-[(3,4,5-trimethoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylateIC5050000.0 [1]
Lyp-IN-1IC5015000.0 [1]
3-[2-Azaspiro[5.5]undecan-2-yl-(1-propan-2-yltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC5075000.0 [1]
N-(4-Fluoro-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amineIC5038000.0 [1]
6-Hydroxy-3-iodo-1-methyl-2-[3-[[2-oxo-2-(4-thiophen-3-ylanilino)acetyl]amino]phenyl]indole-5-carboxylic acidIC501030.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-lc-ptp-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-lc-ptp-inhibitors-ic50-ki.
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